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Medicine composition for curing tumour and preparation method thereof

A composition and drug technology, applied in the field of drugs, can solve the problems of high mortality and high cost

Active Publication Date: 2013-12-25
GUIZHOU SHENQI PHARMA RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the high cost of cancer treatment and the high mortality rate, many patients in less developed countries and regions will give up treatment, so the actual number of cancer patients in the world is greater than the above figures

Method used

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  • Medicine composition for curing tumour and preparation method thereof
  • Medicine composition for curing tumour and preparation method thereof
  • Medicine composition for curing tumour and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Prescription: sodium cantharidinate 20mg, dihydroartemisinin 600mg, leopard frog enzyme 5mg

[0051] The preparation process of the injection is as follows: mix the above-mentioned sodium cantharidinate, dihydroartemisinin and leopard frog enzyme, add water for injection to 1000ml, filter with a 0.45 μm microporous membrane, stir for 20 minutes to mix evenly, potting , Sterilize to obtain the injection preparation.

[0052] Usage and dosage: intravenous injection or intravenous infusion, 5-20ml each time, once a day.

Embodiment 2

[0054] Prescription: sodium cantharidinate 50mg, dihydroartemisinin 500mg, leopard frog enzyme 1mg

[0055] The preparation process is as follows: take the above-mentioned sodium cantharidinate, dihydroartemisinin, leopard frog enzyme, 250ml of glycerin, lactose, 100g of mannitol, mix evenly, add water for injection to 1000ml, adjust the pH of the liquid to 7, filter, fill, and freeze Dry to obtain freeze-dried powder. The freeze-drying process is as follows: the filled vials are half-corked and sent to a freeze dryer, slowly frozen to below -15°C, vacuumed to 5-10Pa, and controlled to heat up at a rate of no more than 4°C / h for sublimation. After 10 hours of sublimation, set the shelf temperature to 20°C for the second drying. When the product temperature is close to the shelf temperature, dry at a constant temperature for 0.5-1 hour and then fully press the plug.

[0056] Usage and dosage: intravenous injection or intravenous drip, 0.5-5mg each time, once a day. Dissolve i...

Embodiment 3

[0058] Prescription: sodium cantharidinate 10g, dihydroartemisinin 5g, leopard frog enzyme 0.01g

[0059] The preparation process is as follows: mix the above-mentioned sodium cantharidinate, dihydroartemisinin and leopard frog enzyme, add 10Kg of sodium chloride and mix at the same time, add water for injection to 100L, adjust the pH to 6, filter with a 0.22μm microporous membrane, and stir for 20 Minutes to mix evenly, subpackage, and sterilize to obtain a large-volume injection.

[0060] Usage and dosage: intravenous injection or intravenous drip, 500-1000ml each time, once a day.

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Abstract

The invention discloses a medicine composition for curing tumour and a preparation method thereof, which is prepared by sodium cantharidinate, dihydroartemisinin, leopard frog enzyme and auxiliary materials. The medicine composition can improve immunity of organisms, directly kills tumour cells, is obvious in effects, is lower in toxicity and side effects compared with traditional chemoradiotherapy medicine, can serve as substitution medicine or important biological medicine for curing cancer, and brings good news to cancer patients.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating tumors and a preparation method thereof, belonging to the technical field of medicines. Background technique [0002] Tumor has always been a serious disease that endangers human health and even life. Tumor brings difficulties and physical pain to patients, and brings a series of problems and serious losses to the country. Since 1996, there have been more than 10 million newly diagnosed cancer patients worldwide each year, and more than 7 million deaths. By the end of 1999, the total number of cancer patients worldwide had exceeded 40 million. By the year 2000, according to the data of the Ministry of Health Information Center, the mortality rate of malignant tumors in cities has increased significantly, an increase of 30.24% compared with ten years ago. However, due to the high cost of cancer treatment and the high mortality rate, many patients in less developed countries and regions ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/46A61P35/00A61K31/34A61K31/357
Inventor 张芝庭
Owner GUIZHOU SHENQI PHARMA RES INST