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A drug delivery device

A delivery device and drug technology, applied in the field of medical devices, can solve problems such as inability to achieve directional drug delivery in diseased blood vessels, major side effects of normal blood vessels, and vascular restenosis, and achieve the effects of repairing vascular endothelial damage, inhibiting cell proliferation, and avoiding coagulation.

Active Publication Date: 2015-10-28
SHANGHAI VASOLUTIONS MEDTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the process of realizing the present application, the inventors found that there are at least the following problems in the prior art: whether it is a balloon dilatation operation or a stent placement operation, some complications may be brought about, such as inflammation, vascular intima tear, Hyperplasia of vascular endothelial cells, etc., which may lead to vascular restenosis
However, delivery of certain anti-inflammatory and anti-cell proliferation drugs to diseased blood vessels by oral administration or injection has a certain effect on inhibiting vascular restenosis, but it cannot achieve directional drug delivery to diseased blood vessels, and has a greater effect on normal blood vessels. side effects

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0025] figure 1 It is a schematic cross-sectional structure diagram of a drug delivery device provided in an embodiment of the present application.

[0026] like figure 1 As shown, the drug delivery device is a coaxial balloon dilatation catheter, including: a push rod 1, an inner tube 2, a balloon 3, a development mark 4, a stress diffusion tube 5 and a connecting device 6, wherein: the push rod 1 is hollow Structure, the distal end is sealed and fixed with the balloon 3, and the proximal end is sealed and fixed with the connecting device 6; the inner tube 2 is also a hollow structure, which runs through the inner cavity of the balloon 3 and the push rod 1, and is connected with the inner cavity of the push rod 1. The cavity is isolated, the distal end passes through the balloon 3 and is sealed and fixed with the balloon 3, and the proximal end is sealed and fixed with the connection device 6. The connection device 6 is provided with a guide wire port 8 and an injection port...

Embodiment 2

[0033] Figure 5 It is a schematic cross-sectional structure diagram of another drug delivery device provided in the embodiment of the present application.

[0034] In the embodiment of the present application, the proximal opening of the inner tube of the drug delivery device can be arranged not only at the proximal opening of the push rod, but also on the side wall of the push rod.

[0035] like Figure 5 As shown, the drug delivery device also includes: a push rod 1, an inner tube 2, a balloon 3, a developing mark 4, a stress diffusion tube 5 and a connection device 6, wherein the connection device 6 is only provided with an injection port 9, and the guide The thread port 8 is arranged at a proper position outside the push rod 1 , and the proximal opening of the inner tube 2 is sealed and fixed with the guide thread port 8 . The connection relationship of other parts in the drug delivery device is the same as that in Embodiment 1 of the present application.

[0036] In t...

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Abstract

The invention discloses a drug conveying device, comprising a feeding rod, a balloon, an internal tube, a developing mark, a stress diffusion tube and a connection device, wherein a groove is arranged on the surface of the balloon, and a plurality of micropores internally communicated with the interior of the balloon are arranged in the groove. The drug conveying device can be used for directly treating stenosis in a stent or be used for conveying drug to vessels, which are subjected to balloon dilation operation or stent implantation operation. Oriented release of the drug to vascular walls can be realized without the help of any drug coating, so as to repair vascular endothelial injury and restrain hyperplasia of vascular smooth muscle cell. Furthermore, the drug conveying device can be dismounted from a human body after the operation, so as to avoid blood cohesion at vascular pathological change. Therefore, the possibility of vascular restenosis is reduced.

Description

technical field [0001] The present application relates to the technical field of medical devices, in particular to a drug delivery device. Background technique [0002] In recent years, with the aggravation of the aging population in my country and the increase in the incidence of diabetes, the prevalence of cardiovascular and cerebrovascular and peripheral blood vessels has also been increasing. In vascular diseases, arterial stenosis will directly endanger the lives of patients. [0003] Interventional surgery has become an important means of treating arterial stenosis due to its advantages of less bleeding, less trauma, fewer complications, quick postoperative recovery, safety and reliability. Interventional therapy includes balloon dilation surgery and stent implantation surgery, in which the balloon dilation surgery is to directly deliver the balloon dilation catheter to the stenosis of the blood vessel, and the narrow blood vessel is dilated by the balloon; the stent i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M29/02A61M31/00
Inventor 赵振心李孝秀郑忠伟谢志永罗七一
Owner SHANGHAI VASOLUTIONS MEDTECH CO LTD
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