Selenium-enriched marasmius androsaceus toadstool extract preparation and preparation method thereof

A technology of Anluo coriander and extract, which is applied in the field of selenium-enriched Anluo coriander extract preparation and its preparation field, can solve the problems that there is no public report on Anluo courier's selenium-enriched research and the like, and achieve rich The effect of selenium is remarkable, the curative effect is remarkable, the effect of inhibitory activity

Active Publication Date: 2014-05-14
山西康欣药业有限公司 +1
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Problems solved by technology

[0007] According to the retrieval of the international and domestic online and CD-ROM databases of the Shanxi Science and Technology Information Research Institute, according to the retrieved data, there is no public report on the study of selenium-enriched Dermaella anluo

Method used

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Embodiment Construction

[0025] The Dermatomaceous fungus Anluo used in the present invention has a strain number of 5.152, which was introduced from China Common Microorganism Culture Collection and Management Center. Three-stage submerged fermentation culture is adopted, the fermentation process adopts aseptic operation, the extraction process adopts mycelia and bacterial liquid separation, the separated bacterial liquid is concentrated, and the mycelium is dried. Reflux extraction, the concentrated extract of the extract is mixed with the extract of the bacteria liquid, the selenium content in the mixed extract reaches 240-400 μg / g; excipients are added according to the conventional process, and the selenium-enriched Anluo mushroom tablet is made and other preparations.

[0026] The preparation method of selenium-enriched Anluo dermatophyte extract is as follows:

[0027] A. Incline cultivation

[0028] Medium: PDA comprehensive medium + 10mg / 100ml sodium selenite (Na 2 SeO 3 ·5H 2 O), so that...

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Abstract

The invention discloses a selenium-enriched marasmius androsaceus toadstool extract preparation which is prepared by the steps that: based on marasmius androsaceus toadstool as a carrier for enriching selenium element, a liquid submerged fermentation technology is adopted, 10-30mg / ml of sodium selenite (Na2SeO3.5H2O) is added into mycelium and metabolite of the marasmius androsaceus toadstool in the growth process according to the volume weight ratio, so that the selenium content in the cultured product of the marasmius androsaceus toadstool reaches 240-400mu g / g; and an excipient is added according to the conventional technology, so that the selenium-enriched marasmius androsaceus toadstool extract preparation is prepared. The selenium-enriched marasmius androsaceus toadstool extract preparation can be used as a medicine for treating multiple pain diseases such as nervous headache, pain in waist and lower extremities, sciatica and the like, and is remarkable in treatment effect; compared with the similar medicines, the selenium-enriched marasmius androsaceus toadstool extract preparation has the characteristics of being high in cure rate, free from side effect or addiction and the like; and the selenium-enriched marasmius androsaceus toadstool extract preparation is simple in production technique, convenient in operation and remarkable in selenium enrichment effect, and has potential application and development values.

Description

technical field [0001] The invention relates to a fungus extract preparation and a preparation method thereof, in particular to an extract preparation of selenium-enriched Dermatophytum agaricus and a preparation method thereof. Background technique [0002] Selenium is an essential trace element for the human body. Selenium has the functions of scavenging free radicals, anti-inflammation, anti-tumor and anti-lipid oxidation. It also has functions of delaying aging and improving the body's immunity. Directly adding inorganic selenium salts in medicines and foods has low biological activity, is not only difficult to absorb, but also has toxic and side effects, and the use effect is not ideal. At present, people mainly rely on food to obtain selenium. Compared with inorganic selenium, bio-sourced organic selenium has the advantages of high absorption and utilization, safety and non-toxicity. 72% of my country's regions are selenium-deficient areas, and the selenium content in...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12P1/02A61K36/06A61P3/02A61P29/00A61K33/04
Inventor 郭战平赵金芬
Owner 山西康欣药业有限公司
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