Traditional Chinese medicine for preventing and curing recurrent aphthae and preparing method thereof

A technology of traditional Chinese medicine and components, applied in the field of medical engineering, can solve the problems of recurrent aphthous ulcers that cannot be cured, strong irritation of the digestive tract, and poor pertinence, and achieve high-efficiency prevention and treatment, no drug resistance, and low price Effect

Inactive Publication Date: 2013-12-11
CHANGSHU HUAGANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned existing Chinese patent medicines for the treatment of recurrent aphtha can temporarily relieve symptoms, they also cause discomfort in the mouth and cannot radically cure recurrent aphtha.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0058] The present invention also provides a preparation method of a traditional Chinese medicine for preventing and treating recurrent aphthous sores. When the dosage form of the traditional Chinese medicine is a capsule, it includes:

[0059] In the first step, the components are mixed in proportion, and ethanol with an alcohol concentration of 80% to 90% is added for heating and reflux extraction for 2 to 4 times. The obtained extracts are combined, filtered, and concentrated under reduced pressure to remove 80% by mass. ~90% ethanol to obtain a concentrated solution, the mass of ethanol added is 2~4 times the mass of the mixture;

[0060] In the second step, the above concentrated solution is passed through a macroporous adsorption resin column, first eluted with 3 to 5 times the volume of the resin column deionized water or distilled water, and then 2 to 4 times the volume of the resin column with an alcohol concentration of 90%-95% Ethanol elution, collect ethanol eluate, con...

Embodiment 1

[0074] Example 1 Toxicity test of the traditional Chinese medicine of the present invention

[0075] Experimental drug

[0076] South Ginseng 23g, Evodia 15g, Cinnamon 9g, Qianghuo 14g, Aloe 32g, Indigo Naturalis 38g, Gallnut 15g, Dogwood 22g, Cistanche 18g, Oldenlandia diffusa 25g, Sophora flavescens 25g, Polygala 12g, Ebony 22g, Coptis 68g, Plantain 20g of senna, 16g of senna, 15g of puerariae, 25g of medlar, 35g of rehmannia, 32g of peony bark, 28g of licorice and 25g of Atractylodes macrocephala, mixed with 1600g of ethanol with 90% alcohol concentration and refluxed for 3 times, and the obtained extract Combine, filter, concentrate under reduced pressure to remove 80% of the mass percentage of ethanol to obtain a concentrated solution. The concentrated solution is passed through a 6LAB-8 type macroporous adsorption resin column, first eluted with 4 times the volume of the resin column of deionized water, and then used The alcohol concentration of 4 times the volume of the res...

Embodiment 2

[0079] Example 2 Preparation of capsules

[0080] South Ginseng 23g, Evodia 15g, Cinnamon 9g, Qianghuo 14g, Aloe 32g, Indigo Naturalis 38g, Gallnut 15g, Dogwood 22g, Cistanche 18g, Oldenlandia diffusa 25g, Sophora flavescens 25g, Polygala 12g, Ebony 22g, Coptis 68g, Plantain 20g of senna, 16g of senna, 15g of puerariae, 25g of medlar, 35g of rehmannia, 32g of peony bark, 28g of licorice and 25g of Atractylodes macrocephala, mixed with 1600g of ethanol with 90% alcohol concentration and refluxed for 3 times, and the obtained extract Combine, filter, concentrate under reduced pressure to remove 80% of the mass percentage of ethanol to obtain a concentrated solution. The concentrated solution is passed through a 6LAB-8 type macroporous adsorption resin column, first eluted with 4 times the volume of the resin column of deionized water, and then used The alcohol concentration of 4 times the volume of the resin column is 95% ethanol elution. Collect the ethanol eluate, concentrate it ...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for preventing and curing recurrent aphthae and a preparing method thereof, which comprises ingredients of upright ladybell root, evodia rutaecarpa, cinnamonum cassia, notopterygium root, aloe, indigo naturalis, Chinese gall, cornus officinalis, cistanche deserticola, oldenlandia diffusa, sophora flavescens, polygala tenuifolia, dark plum fruit, coptis chinensis, plantain seed, senna leaf, kudzuvine root, fructus lycii, dried rehmannia root, tree peony bark, licorice and bighead atractylodes rhizome. The traditional Chinese medicine for preventing and curing recurrent aphthae has the advantages of high efficiency and little toxic and side effect, being free of residue, drug resistance and environment pollution, quick effect, low cost and being worthy of popularization on prevention and treatment of recurrent aphthae.

Description

Technical field [0001] The invention belongs to the technical field of medical engineering, and particularly relates to a traditional Chinese medicine for preventing and treating recurrent aphthous sores. Background technique [0002] Recurrent aphthous ulcers are Western medicine recurrent ulcers (recurrent ulcer ROU), also known as recurrent aphthous ulcers (RAU), which are isolated or multiple oral mucosal ulcers that appear irregularly or periodically in any part of the oral mucosa. It is the most common oral mucosal disease in the clinic, with scattered superficial ulcers in the oral mucosa and local burning pain as its clinical characteristics, and it has the characteristics of limitation, recurrence, and self-healing. [0003] Although recurrent aphthous ulcers are not serious or serious diseases, and have no obvious systemic symptoms, they still affect daily life and work, especially when talking or eating are very inconvenient, leading to eating disorders, tasteless eating...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K9/48A61K9/12A61K9/70A61P1/02
Inventor 戴忠明
Owner CHANGSHU HUAGANG PHARMA
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