Nanoemulsion composition for treating mycoplasma pneumonia of livestock and preparation method of nanoemulsion composition
A technology of mycoplasma pneumonia and nanoemulsion, which is applied in the direction of drug combination, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve uneven stirring, narrow medicinal fields, and large animal stress, etc. problems, to achieve the effects of high thermodynamic stability, improved bioavailability, and simple method and process
Inactive Publication Date: 2012-07-25
NORTHWEST A & F UNIV
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Problems solved by technology
[0006] At present, the majority of farmers mainly use traditional methods such as traditional Chinese medicine powder mixing and injection intramuscular injection for the treatment of livestock and poultry mycoplasma pneumonia. When mixing Chinese medicine powder, it is easy to appear uneven stirring, causing some animals to eat too much, and some The situation that some animals cannot eat, and the appetite of livestock and poultry is often low after the onset of the disease, and the utilization rate of the medicine will be very low; the injection has a good therapeutic effect, but it is highly irritating to t
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Embodiment 2
[0063] Rue oil 8.0g, vitex oil 1.0g, perilla seed oil 0.1g, bupleurum oil 0.2g, allicin 0.05g, tiamulin fumarate 2.5g, Tween-80 28.0g, distilled water 61.05g.
Embodiment 3
[0065] Rue oil 2.0g, vitex oil 5.0g, perilla seed oil 0.2g, bupleurum oil 0.1g, allicin 0.05g, tiamulin fumarate 2.8g, Tween-80 26.0g, distilled water 63.85g.
Embodiment 4
[0067] Rue oil 4.3g, vitex oil 2.9g, perilla seed oil 3.0g, Bupleurum oil 0.9g, allicin 0.08g, tiamulin fumarate 3.5g, Tween-80 22.8g, distilled water 62.52g.
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Abstract
The invention discloses a nanoemulsion composition for treating mycoplasma pneumonia of livestock, which consists of raw materials including, by mass percent, from 0.1 to 8.0% of amyris oil, from 0.1 to 5.0% of vitex oil, from 0.1 to 3.0% of perilla oil, from 0.1 to 2.0% of bupleurum oil, from 0.01 to 0.1% of allicin, from 0.1 to 4.0% of tiamulin fumarate, from 19.0% to 31.0% of surfactant and the balance distilled water. The sum of the mass ratios of the ingredients is 100%. The nanoemulsion composition has effects of dilating the trachea of the livestock, suppressing cough reflex, increasing immunity of the organism, resisting inflammation and killing mycoplasma pneumoniae or other mixed infected causative agent, can be used for preventing and curing respiratory diseases including chronic respiratory diseases of the livestock, mycoplasma pneumoniae of swine, porcine contagious pleuropneumonia and the like, is fine in stability, is high in intestinal absorption utilization rate after being orally taken, can avoid liver first pass effect, and is remarkable in curative effect.
Description
technical field [0001] The invention belongs to the field of veterinary medicine, and relates to a nanoemulsion composition and a preparation method thereof which can be used for treating respiratory diseases such as poultry chronic respiratory disease, swine panting disease and infectious pleuropneumonia. [0002] Background technique [0003] Respiratory diseases are common and frequently-occurring diseases in the process of livestock and poultry breeding. Especially in recent years, with the development of the economy and the improvement of people's consumption level, the market's demand for meat, eggs, and milk has continued to increase. Traditional farming has gradually transformed into modern intensive farming, and the number of livestock and poultry breeding has increased to an unprecedented scale. . In addition, the current management system in my country is not yet perfect, and the abuse of antibiotics selects drug-resistant strains, etc., resulting in a high inci...
Claims
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IPC IPC(8): A61K36/85A61K47/26A61K9/107A61P11/00A61P11/06A61P31/04A61K31/22A61K31/10
Inventor 欧阳五庆郭建军欧阳伸雨
Owner NORTHWEST A & F UNIV
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