System and method for processing nucleic acid sequencing information

A nucleic acid sequencing and processing method technology, applied in the field of information processing, can solve problems such as low matching efficiency and inaccurate matching of nucleic acid sequence fragments, and achieve the effect of high matching accuracy and fast speed

Active Publication Date: 2012-09-19
深圳麦芽加速器科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a nucleic acid sequencing information processing system and method, aiming to solve the problems of inaccurate and low matching efficiency of nucleic acid sequence fragments in the prior art

Method used

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  • System and method for processing nucleic acid sequencing information
  • System and method for processing nucleic acid sequencing information
  • System and method for processing nucleic acid sequencing information

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no. 1 example

[0047] The processing system of this embodiment realizes the accuracy and high efficiency of the nucleic acid sequencing information processing system as a whole. Based on the first embodiment, the present invention proposes a second embodiment, such as figure 2 shown. In this embodiment, the short segment creation unit may include a first decision module and a first segmentation module. The two modules described are described in detail below.

[0048] (1) The first decision-making module 111 is configured to obtain the shortest nucleic acid sequence fragment, and send the nucleic acid sequence fragment and the number of bases of the nucleic acid sequence fragment to the first segmentation module 111 .

[0049] A shortest nucleic acid sequence fragment is selected from all nucleic acid sequence fragments, and the length of the nucleic acid sequence is q. The method of obtaining the shortest nucleic acid sequence fragment is not limited, and it can be obtained by screening ...

no. 4 example

[0094] According to the fourth embodiment, the system may further include a nucleic acid sequencing unit.

[0095] (2) The nucleic acid sequencing unit is used to sequence nucleic acid to obtain nucleic acid sequence fragments, and send the nucleic acid sequence fragments to the short fragment creation unit.

[0096] The nucleic acid sequence unit may include a nucleic acid detection device and a data processing device for sequencing. Wherein, the nucleic acid sequence detection device is used to sequence unknown nucleic acid to obtain sequencing data; the data processing device is used to process the sequencing data to obtain nucleic acid sequence fragments. The nucleic acid sequencing device and data processing device are not particularly limited. Nucleic acid detection devices and corresponding data processing devices sold on the market are applicable to the present invention. The nucleic acid detection device can be a high-throughput gene sequencer, a gene chip, etc., and ...

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Abstract

The invention relates to the field of information processing and provides a system and a method for processing nucleic acid sequencing information. The system comprises a short-segment establishing unit, a database establishing unit and a sequence matching unit. The short-segment establishing unit is used for segmenting each nucleic acid sequence segment to establish short segments, the database establishing unit is used for establishing referential sequence indexes and storing the short segments to obtain a database, and the sequence matching unit is used for respectively matching the short segments established by segmenting each nucleic acid sequence segment in the database individually. The invention further comprises a method based on the system. The technical scheme of the system and the method for processing the nucleic acid sequencing information can realize accurate and quick matching of nucleic acid sequence segments.

Description

technical field [0001] The present invention relates to the field of information processing, and more specifically, to a nucleic acid sequencing information processing system and method. Background technique [0002] With global efforts, human beings have completed the nucleic acid sequencing of various organisms. In the second-generation nucleic acid sequencing technology, human beings make full use of known nucleic acid to sequence individuals, and search for individual mutated genes, so as to provide information for individuals. Provides a reliable basis for the expressiveness of the present. [0003] In the prior art, multiple nucleic acid sequence fragments (called reads, and one nucleic acid sequence fragment is called read) are obtained through sequencing and analysis, and each read is randomly divided into 4 segments, which are sequentially marked as a, b, c, and d. Combine a, b, c, and d to form short nucleic acid sequence fragments, that is, form three short fragm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/22
Inventor 盛司潼
Owner 深圳麦芽加速器科技有限公司
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