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Application of Awei capsules to preparation of drugs for treating hyperlipemia and fatty liver disease

A technology for hyperlipidemia and fatty liver, which is applied in the application field of preparing a drug for treating hyperlipidemia and fatty liver, can solve the problems of rebound after drug withdrawal, single lipid-regulating effect, and easy to cause other diseases, such as liver function.

Inactive Publication Date: 2012-09-26
XINJIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The drugs provided by modern medicine for hyperlipidemia are mostly based on the single-target mechanism of action, and their defects lie in the single effect of lipid-lowering, rebound after drug withdrawal, and easy to cause other diseases and liver damage, etc.
At present, traditional Chinese medicine treats hyperlipidemia based on syndrome differentiation of phlegm turbidity and blood stasis. In the treatment, the method of promoting blood circulation to remove blood stasis and promoting dampness to relieve turbidity is basically adopted. Although this method significantly reduces side effects, the treatment cycle is longer , the curative effect is mediocre, so it is of great significance to find a drastic, safe and fast treatment plan from the theory of traditional Chinese medicine

Method used

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  • Application of Awei capsules to preparation of drugs for treating hyperlipemia and fatty liver disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Example 1, the application of Ferulic Capsules in the preparation of medicines for treating hyperlipidemia and fatty liver.

Embodiment 2

[0016] Example 2, the Ferulic Capsules in Example 1 are obtained according to the following steps: the first step is to prepare medicinal materials, ferulus 8g, ginseng ginseng 750g, Magnolia officinalis 750g, comfrey 750g, Arrowhead mushroom 750g, Rhizoma Imperatae 1500g; The second step is to obtain the mixed fine powder of Ferulicum and Imperatae Rhizome, and the above-mentioned amount of Ferulicum and 38g of Imperatae Rhizome mixed oil are pulverized into the mixed fine powder of Ferulicum and Imperatae Rhizome, and set aside; the third step is to obtain the alcohol extraction Thing, get above-mentioned Magnolia officinalis officinale, comfrey plus 6 times of its amount of 80% mass percentage concentration of ethanol aqueous solution reflux extraction 2 times, each 1.5 hours, merge extracts, filter, obtain alcohol extraction filtrate for subsequent use; Step by step to obtain ferulic capsules, the rest of the above-mentioned medicinal materials, i.e. Shanzigu, Imperatae Rhi...

Embodiment 3

[0017] Embodiment 3, the dosage of the Ferulic Capsules of Embodiment 1 and Embodiment 2 is 3 times a day, each 5, each 0.43g.

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Abstract

The invention relates to the field of application technology of preparing drugs used for treating hyperlipemia and fatty liver disease, and relates to application of Awei capsules to preparation of drugs for treating hyperlipemia and fatty liver disease. SD (Sprague Dawley) rats are divided into five groups, namely a normal control group, a hyperlipemia model control group, an Awei capsule high-dose group, an Awei capsule medium-dose group and an Awei capsule low-dose group, which are fed with high fat diet. The SD rats in the Awei capsule high-dose group, the Awei capsule medium-dose group and the Awei capsule low-dose group are subjected to gavage with Awei capsules in different doses for seven weeks, various indexes of the SD rats are observed and analyzed, data and pictures show that the SD rats subjected to gavage in the Awei capsule high-dose group, the Awei capsule medium-dose group and the Awei capsule low-dose group are improved better as compared with the SD rats in the hyperlipemia model control group, and accordingly the effects of the Awei capsules on blood lipid regulating, antioxidation enhancing, fatty liver disease preventing and liver function improving are testified further.

Description

technical field [0001] The invention relates to the technical field of application in the preparation of medicines for treating hyperlipidemia and fatty liver, and relates to the application of Ferulic Capsules in the preparation of medicines for treating hyperlipidemia and fatty liver. Background technique [0002] Hyperlipidemia is a modern medical disease name, which is not recorded in traditional Chinese medicine literature and has not yet formed a unified disease name. Some Chinese medicine scholars have named it "blood turbidity" according to the etiology and pathogenesis characteristics. Modern medicine regards blood lipid four as diagnosis and treatment standard. The drugs provided by modern medicine for hyperlipidemia are mostly based on a single-target mechanism of action, and their defects lie in a single lipid-lowering effect, rebound after drug withdrawal, and easy to cause other diseases and liver damage. At present, traditional Chinese medicine treats hyperli...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K36/23A61K9/48A61P3/06A61P1/16
Inventor 韩荣薛洁孟军周倩张洪平赵翡翠
Owner XINJIANG MEDICAL UNIV
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