Application of Awei capsules to preparation of drugs for treating hyperlipemia and fatty liver disease

A technology for hyperlipidemia and fatty liver, which is applied in the application field of preparing a drug for treating hyperlipidemia and fatty liver, can solve the problems of rebound after drug withdrawal, single lipid-regulating effect, and easy to cause other diseases, such as liver function.

Inactive Publication Date: 2012-09-26
XINJIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The drugs provided by modern medicine for hyperlipidemia are mostly based on the single-target mechanism of action, and their defects lie in the single effect of lipid-lowering, rebound after drug withdrawal, and easy to cause other diseases and liver damage, etc.
At present, traditional Chinese medicine treats hyperlipidemia based on syndrome differentiation of phlegm turbidity and blood stasis.

Method used

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  • Application of Awei capsules to preparation of drugs for treating hyperlipemia and fatty liver disease

Examples

Experimental program
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Effect test

Example Embodiment

[0015] Example 1, the application of Asafoetida capsules in the preparation of drugs for treating hyperlipidemia and fatty liver.

Example Embodiment

[0016] In Example 2, the Asafoetida capsule in Example 1 was obtained according to the following steps: the first step is to prepare medicinal materials, 8g Asafoetida, Fistula 750g, Magnolia officinalis 750g, Lithospermum 750g, Shanji mushroom 750g, and Imperata root 1500g; The second step is to obtain the mixed fine powder of Asafoetida and Imperata cylindrica root, the above-mentioned amount of Asafoetida and 38g of Imperata cylindrica root medicinal material mixed string oil is pulverized into a mixed fine powder of Asafoetida and Imperata cylindrica root for use; the third step is to obtain alcohol extraction Take the above-mentioned amount of Magnolia officinalis and Lithospermum erythrorhizon plus 6 times the amount of 80% by weight of the ethanol aqueous solution for reflux extraction twice, 1.5 hours each time, combine the extracts, filter, and obtain the alcohol extraction filtrate for later use; Step by step to obtain Asafoetida Capsules, decoct and extract the other ...

Example Embodiment

[0017] The dosage of the asafoetida capsules in Example 3, Example 1 and Example 2 is 3 times a day, 5 capsules each time, 0.43 g per capsule.

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Abstract

The invention relates to the field of application technology of preparing drugs used for treating hyperlipemia and fatty liver disease, and relates to application of Awei capsules to preparation of drugs for treating hyperlipemia and fatty liver disease. SD (Sprague Dawley) rats are divided into five groups, namely a normal control group, a hyperlipemia model control group, an Awei capsule high-dose group, an Awei capsule medium-dose group and an Awei capsule low-dose group, which are fed with high fat diet. The SD rats in the Awei capsule high-dose group, the Awei capsule medium-dose group and the Awei capsule low-dose group are subjected to gavage with Awei capsules in different doses for seven weeks, various indexes of the SD rats are observed and analyzed, data and pictures show that the SD rats subjected to gavage in the Awei capsule high-dose group, the Awei capsule medium-dose group and the Awei capsule low-dose group are improved better as compared with the SD rats in the hyperlipemia model control group, and accordingly the effects of the Awei capsules on blood lipid regulating, antioxidation enhancing, fatty liver disease preventing and liver function improving are testified further.

Description

technical field [0001] The invention relates to the technical field of application in the preparation of medicines for treating hyperlipidemia and fatty liver, and relates to the application of Ferulic Capsules in the preparation of medicines for treating hyperlipidemia and fatty liver. Background technique [0002] Hyperlipidemia is a modern medical disease name, which is not recorded in traditional Chinese medicine literature and has not yet formed a unified disease name. Some Chinese medicine scholars have named it "blood turbidity" according to the etiology and pathogenesis characteristics. Modern medicine regards blood lipid four as diagnosis and treatment standard. The drugs provided by modern medicine for hyperlipidemia are mostly based on a single-target mechanism of action, and their defects lie in a single lipid-lowering effect, rebound after drug withdrawal, and easy to cause other diseases and liver damage. At present, traditional Chinese medicine treats hyperli...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K36/23A61K9/48A61P3/06A61P1/16
Inventor 韩荣薛洁孟军周倩张洪平赵翡翠
Owner XINJIANG MEDICAL UNIV
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