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Composition for increasing bone mineral density, preparation agent containing same, and preparation method of same

A technology for increasing bone density and composition, applied in the field of compositions for increasing bone density, can solve problems such as limiting the collection of bone peptide raw materials, and achieve excellent effects

Active Publication Date: 2012-10-03
HARBIN ZHENBAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The drug limits the collection of bone peptide raw materials

Method used

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  • Composition for increasing bone mineral density, preparation agent containing same, and preparation method of same
  • Composition for increasing bone mineral density, preparation agent containing same, and preparation method of same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: increase the tablet of bone density (0.5 gram / tablet)

[0035] 1. Raw materials and auxiliary materials: calcium carbonate 0.5kg, glucosamine sulfate 0.5kg, chondroitin sulfate 0.05kg, collagen 0.1kg, turmeric extract 0.08kg, microcrystalline cellulose 0.4kg, corn starch 0.32kg, magnesium stearate 0.01kg.

[0036] 2. Preparation method:

[0037] Mix calcium carbonate, glucosamine sulfate, chondroitin sulfate, collagen and microcrystalline cellulose for 20 minutes, add 8% starch slurry and stir for 10 minutes, granulate with 18 mesh sieve, dry at 45°C for 20 minutes, 18 mesh sieve Whole grains, add turmeric extract and magnesium stearate, mix evenly and press into tablets to obtain.

Embodiment 2

[0038] Embodiment 2: increase the tablet of bone density (0.5 gram / tablet)

[0039] 1. Raw materials and auxiliary materials: calcium carbonate 35g, glucosamine sulfate 30g, chondroitin sulfate 3g, collagen 10g, turmeric extract 5g, dextrin 25.3g, corn starch 22.5g, magnesium stearate 0.7g, carboxymethyl starch Sodium 2.8g.

[0040] 2. Preparation method:

[0041] Mix the formula amount of calcium carbonate, glucosamine sulfate, chondroitin sulfate, collagen and dextrin for 20 minutes, add 15% starch slurry and stir for 30 minutes, granulate with 18 mesh sieve, dry at 55°C for 40 minutes, granulate with 18 mesh sieve , add turmeric extract, magnesium stearate and sodium hydroxymethyl starch, mix well and press into tablets to obtain.

Embodiment 3

[0042] Embodiment 3: increase the tablet of bone density (0.5 gram / tablet)

[0043] 1. Raw materials and auxiliary materials: calcium carbonate 2kg, glucosamine sulfate 2kg, chondroitin sulfate 0.2kg, collagen 0.5kg, turmeric extract 0.3kg, dextrin 2.4kg, magnesium stearate 0.04kg, sodium carboxymethyl starch 0.2 kg.

[0044] 2. Preparation method:

[0045] Mix calcium carbonate, glucosamine sulfate, chondroitin sulfate, collagen and dextrin in the prescribed amount for 30 minutes, add 12% starch slurry and stir for 2 minutes, granulate with 18 mesh sieve, dry at 50°C for 30 minutes, granulate with 18 mesh sieve , add turmeric extract and magnesium stearate, mix well and press into tablets to obtain.

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PUM

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Abstract

The invention relates to a composition for increasing bone mineral density, a preparation agent containing the composition, and the preparation method of same. The composition comprises the following raw materials according to the weight portions: 0.5 to 35 portions of calcium carbonate, 0.5 to 30 portions of sulfuric acid dextrosamine, 0.05 to 2 portions of sulfuric acid chondroitin, 0.1 to 10 portions of collagen, and 0.08 to 5 portions of turmeric yellow extractive. In the composition, except a calsium supplement and a calcium absorbing promoting agent, the composition further comprises nutrients and anti-inflammatory mitigative, and can be used for preventing and treating osteoporotic symptom from multiply angles and ways.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a composition for increasing bone density, its preparation and its preparation method. Background technique [0002] Osteoporosis (osteoporosis) is a systemic bone disease, characterized by decreased bone mass and destruction of bone microstructure, manifested as increased bone fragility, thus greatly increasing the risk of fracture, even with minor trauma or Fractures are also prone to occur in the absence of trauma. Osteoporosis is a multifactorial chronic disease. Before the fracture occurs, there are usually no special clinical manifestations. The disease is more common in women than in men and is common in postmenopausal women and the elderly. With the increase of the elderly population in my country, the incidence of osteoporosis is on the rise, and it is a health problem worthy of attention in my country and even in the world. [0003] CN201110074629.7 relates to a chond...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61P19/10A61P29/00A23L1/29A61K36/9066A61K31/7008A61K33/10A61K31/737A23L33/00
Inventor 方同华张韬韩磊倪蓓
Owner HARBIN ZHENBAO PHARMA
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