Immunostimulatory injection for livestock
An immune activation and injection technology, applied in the field of injection, can solve the problems of pH value change, inconvenient use, short storage time, etc., and achieve the effects of low cost control, enhanced bactericidal function, and less toxic and side effects
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Embodiment 1
[0026] Immune activation injection (1ml is equivalent to 0.4g of the original drug)
[0027] 1. Formula
[0028] Astragalus 20g, Bupleurum 10g, tangerine peel 10g, pH regulator 0.2g, activated carbon 0.2g, PEG400 dosage 40ml, benzyl alcohol 1ml, water for injection to 100ml.
[0029] 2: Preparation method
[0030] Step 1: Take the prescription amount of astragalus and tangerine peel, slice them, add 5 times the weight of water for injection and decoct twice, the first time for 2 hours, the second time for 1 hour, combine the decoction, filter, and concentrate the filtrate to twice the amount of traditional Chinese medicine When it is cooled to 40°C, slowly add ethanol to make the alcohol content reach 75%, stir well, let it stand for 12 hours, filter the supernatant, add an appropriate amount of 75% ethanol to the residue, stir well, let stand for 12 hours , filtered, combined the ethanol solution, recovered the ethanol until it had no alcohol smell, and prepared A solution ...
Embodiment 2
[0034] Immune activation injection (1ml is equivalent to 0.3g of the original drug)
[0035] 1. Formula
[0036] Astragalus 15g, Bupleurum 7.5g, tangerine peel 7.5g, pH regulator 0.2g, activated carbon 0.15g, PEG400 30ml, benzyl alcohol 1ml, water for injection to 100ml.
[0037] 2: Preparation method: the same as the method described in Example 1.
Embodiment 3
[0039] Immune activation injection (1ml is equivalent to 0.2g of the original drug)
[0040] 1. Formula
[0041] Astragalus 10g, Bupleurum 5g, tangerine peel 5g, pH regulator 0.1g, activated carbon 0.1g, PEG400 20ml, benzyl alcohol 1ml, water for injection to 100ml.
[0042] 2: Preparation method: the same as the method described in Example 1.
[0043] 1. Accelerated stability test of immune activation injection
[0044] 1. Materials and methods: Take the immune activation injection of Example 1-3, and carry out high-temperature, high-humidity, and strong-light acceleration experiments according to the drug stability test method in the first appendix of the "Chinese Veterinary Pharmacopoeia" 2010 edition, according to commercially available packaging, at a temperature of 40 Place in a drug stability test box (Chongqing Yongsheng Experimental Instrument Factory) at ±2°C, relative humidity 75±5%, and illuminance 4500±500LX for 6 months, and take samples at the end of the first...
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