Pharmaceutical composition for treating constipation and application thereof

Abstract

The invention discloses a pharmaceutical composition for treating constipation and application of the pharmaceutical composition. The pharmaceutical composition contains the following effective components in parts by weight: 10-30 parts of water-soluble dietary fiber, 10-20 parts of glutamine and 1-3 parts of mixed probiotics microbial inoculums consisting of bacillus subtilis, lactobacillus acidophilus and lactobacillus bulgaricus. The pharmaceutical composition has the efficacies of softening excrement, promoting intestine peristalsis, restoring intestinal flora balance, repairing impaired intestinal mucosa, restoring the normal physiological function of intestinal tracts, and treating constipation fundamentally. The components of the composition achieve respective effects to alleviate constipation symptoms, and promote mutually and cooperate with each other to enhance curative effects, and the use effect of the pharmaceutical composition is obviously better than single use of each component.

Description

Technical field [0001] The invention belongs to the field of pharmacy, and specifically relates to a pharmaceutical composition for treating constipation and its application. Background technique [0002] Constipation is a group of symptoms characterized by decreased bowel frequency, difficulty in defecation or incomplete defecation, dry stool, and hard stool. It is a very common clinical symptom. The incidence of constipation in western countries is about 6%-28%. The prevalence is between 3%-17.6%. Long-term constipation seriously affects the health and quality of life of patients, and can lead to complications such as hemorrhoids, anal fissure, and colon cancer. [0003] At present, most patients with constipation mainly use various laxatives to relieve their symptoms, but laxatives generally cause diarrhea in a short period of time, long-term use has large side effects, and can lead to laxative dependence, which can aggravate constipation after stopping the drug. [0004] At pre...

AI Technical Summary

Problems solved by technology

[0006] A large amount of dietary fiber supplementation from the diet requires a considerable amount of food containing dietary fiber, which may increase the burden on the gastrointestinal tract of the patient, causing delayed gastric emptying, resulting in abdominal distension, epigastric discomfort, belching, loss of appetite, indigestion and other symptoms ; and includes a large amount of insoluble dietary fiber, which can increase the volume of stool, thereby increasing the burden on the intestinal tract, and excessive insoluble dietary fiber will affect the absorption of trace elements

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