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Ointment preparation for treating haemorrhoids and preparation method for ointment preparation

A technology of ointment and hemorrhoids, which is applied in the field of ointments for the treatment of hemorrhoids, can solve the problems of insufficient therapeutic effect, short-term action of drugs on lesions, increased pain of patients and bleeding of hemorrhoids, etc., and is easy to carry and store, Improve the release and penetration ability and keep the wound dry

Inactive Publication Date: 2013-02-13
YUNNAN SUNSAIL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Suppository treatment of hemorrhoids has the following defects: (1) suppository is harder, and it is easy to cause damage to mucous membrane and hemorrhoid wall when it is put into the cavity, which increases patient pain and hemorrhoid bleeding. It is not suitable for use for patients with acute hemorrhoids; (2)
The above-mentioned ointment preparation belongs to water-soluble ointment, and has the following defects in the process of treating hemorrhoids: (1) After the water-soluble agent melts, it is diluted by hemorrhoid secretions, and the texture is very thin, and it is quickly eliminated from the anus, resulting in the effect of the drug on the lesion. Short-lived, not fully therapeutic
(2) Water-soluble matrix ointments are easily contaminated by microorganisms, which can easily affect the quality of drugs

Method used

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  • Ointment preparation for treating haemorrhoids and preparation method for ointment preparation
  • Ointment preparation for treating haemorrhoids and preparation method for ointment preparation
  • Ointment preparation for treating haemorrhoids and preparation method for ointment preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0130] Embodiment 1: 80 parts of Panax notoginseng are pulverized into coarse powder, according to the percolation method under the "Chinese Pharmacopoeia" liquid extract and extract, use 3 times the amount of 70% ethanol as solvent, soak after 24 hours and percolate, and the liquid Recover ethanol, concentrate to a relative density of 1.20-1.25 (50°C), set aside, medicine dregs; and 100 parts of Sophora japonica, 110 parts of Sophora flavescens, 100 parts of Cnidium chinensis, 100 parts of Baiji, 100 parts of Patrinia, and Put 80 parts of amaranth, 65 parts of honeysuckle, 65 parts of mugwort leaves, 65 parts of Fangfeng, and 30 parts of licorice in a multi-functional extraction and concentration tank, distill and extract volatile oil, collect the distillate and add 1 part of polysorbate 80 to dissolve it for later use, add water to decoct the dregs for three times, 2 hours for the first time, 1.5 hours for the second time, and 1 hour for the third time, combine the decoction,...

Embodiment 2

[0131]Embodiment 2: 80 parts of Panax notoginseng are pulverized into coarse powder, according to the percolation method under the "Chinese Pharmacopoeia" liquid extract and extract, use 3 times the amount of 70% ethanol as solvent, soak after 24 hours and percolate, and the liquid Recover ethanol, concentrate to a relative density of 1.20-1.25 (50°C), set aside, medicine dregs; and 100 parts of Sophora japonica, 110 parts of Sophora flavescens, 100 parts of Cnidium chinensis, 100 parts of Baiji, 100 parts of Patrinia, and Put 80 parts of amaranth, 65 parts of honeysuckle, 65 parts of mugwort leaves, 65 parts of Fangfeng, and 30 parts of licorice in a multifunctional extraction and concentration tank, distill and extract volatile oil, collect the distillate and add 2 parts of polysorbate 80 to dissolve it for later use, add water to decoct the dregs for three times, 2 hours for the first time, 1.5 hours for the second time, and 1 hour for the third time, combine the decoction, ...

Embodiment 3

[0132] Example 3: 80 parts of Panax notoginseng are pulverized into coarse powder, according to the percolation method under the "Chinese Pharmacopoeia" liquid extract and extract, use 3 times the amount of 70% ethanol as a solvent, soak after 24 hours and percolate, and the liquid Recover ethanol, concentrate to a relative density of 1.20-1.25 (50°C), set aside, medicine dregs; and 100 parts of Sophora japonica, 110 parts of Sophora flavescens, 100 parts of Cnidium chinensis, 100 parts of Baiji, 100 parts of Patrinia, and Put 80 parts of amaranth, 65 parts of honeysuckle, 65 parts of Artemisia argyi, 65 parts of Fangfeng, and 30 parts of licorice in a multifunctional extraction and concentration tank, distill and extract volatile oil, collect the distillate and add 5 parts of polysorbate 80 to dissolve it for later use. 2 hours for the first time, 1.5 hours for the second time, and 1 hour for the third time, combine the decoction, filter, concentrate the filtrate to a ratio of...

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Abstract

The invention relates to an ointment preparation which is prepared from natural plants used as main pharmaceutic components and specific pharmaceutic adjuvant and is used for treating haemorrhoids, and a preparation method for the ointment preparation. The ointment preparation for treating haemorrhoids is prepared from the flowing raw materials and adjuvant in part by weight: 80 parts of notoginseng root, 80 parts of parslane herb, 110 parts of lightyellow sophora root, 100 parts of common bletilla tuber, 100 parts of selinum japenious seed, 100 parts of dahurian patrinia herb, 65 parts of Chinese mugwort leaf, 100 parts of pagoda tree pod, 65 parts of honeysuckle flower, 65 parts of divaricate saposhnikovia root, 50 parts of alum, 50 parts of borax, 5 parts of borneol, 30 parts of liquoric root, 750 to 850 parts of mineral butter, 30 to 70 parts of wool grease, 1 to 20 parts of dimethylsulfoxide, 1 to 20 parts of silicone, 1 to 10 parts of butyl hydroxy anisd, and 1 to 5 parts of polysorbate 80. The medicine is mainly used for treating acute attack of haemorrhoids, internal hemorrhoids blooding and prolapsing, incarceration, perianal abscess, external hemorrhellood, and mixed hemorrhoid sore pain, relieving swelling of postoperative anus edge, and diminishing inflammation, relieving pain and stopping bleeding of local part of the anus. The medicine can also be used as a health-care product for cleaning the anus.

Description

technical field [0001] The invention relates to an ointment for treating hemorrhoids which is made of natural plants as main medicinal ingredients and supplemented with specific medicinal auxiliary materials, and a preparation method of the ointment. Background technique [0002] Hemorrhoids are human-specific diseases and common frequently-occurring diseases. People will suffer from hemorrhoids in a certain period of life. According to the census, hemorrhoids account for 78.33% of anal diseases. Symptoms such as blood in the stool, pain, swelling, and itching caused by hemorrhoids are extremely harmful to people's health. Hemorrhoids can easily lead to the occurrence of rectal and colon cancer if they do not heal for a long time. The occurrence of hemorrhoids is very common, and in the treatment mode, surgery and oral administration have obvious defects. Applying new technologies and methods in the modern pharmaceutical field to develop low-toxic and high-efficiency drugs...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/06A61P9/14A61K31/045A61K33/06A61K33/22
Inventor 温先敏
Owner YUNNAN SUNSAIL PHARMA
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