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Traditional Chinese medicine composition for treating diarrhea-dominant irritable bowel syndrome and preparation method of traditional Chinese medicine composition

A technology of irritable bowel syndrome and composition, which is applied in the field of traditional Chinese medicine, can solve the problems of unsatisfactory long-term curative effect and high recurrence rate, and achieve the effect of no toxic side effects and drug resistance, low recurrence rate and quick effect

Active Publication Date: 2013-04-10
刘俊
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs have a certain effect on the relief of symptoms, but the long-term curative effect is very unsatisfactory, and the recurrence rate is high.

Method used

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  • Traditional Chinese medicine composition for treating diarrhea-dominant irritable bowel syndrome and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating diarrhea-dominant irritable bowel syndrome and preparation method of traditional Chinese medicine composition

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preparation example Construction

[0071] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition, when the dosage form of the Chinese medicine composition is a soft capsule, specifically:

[0072] The first step is to mix the components in proportion, add ethanol with an alcohol concentration of 65% to 85% at 15 to 25 times the mass of the mixture, stir evenly, seal and soak for 4 to 6 days to obtain a soaking solution, which is passed through percolation Tank percolation, the flow rate is 3~5ml per minute, collect the percolation liquid, filter, the filtrate is under the conditions of -0.09~-0.06MPa, 70~90℃, recover the solvent, and concentrate in vacuum to an extract with a relative density of 1.15-1.20;

[0073] The second step is to absorb the macroporous resin on the extract, and the mass ratio of the mass of the extract to the macroporous adsorbing resin is 2 to 3:1. First, wash it with water until the effluent is colorless, and then use it with respect...

Embodiment 1

[0082] The concrete preparation of embodiment 1 oral liquid 1

[0083] 27g of Evodia rutaecarpa, 24g of flying grass, 82g of Atractylodes macrocephala, 29g of citrus aurantium, 56g of gall, 31g of black plum, 25g of red cardamom, 36g of Tibetan calamus, 25g of pine pollen, 52g of white lentils, 35g of licorice, 33g of lotus seeds, 44g of psoraleae, catechin 18g, Mingdangshen 38g, Fangfeng 42g, betel nut 24g, bergamot 31g, agarwood 26g, coix seed 32g, 25g galanga, galangal 31g, coptis 38g, toon bark 32g, golden fruit olive 21g, add 75kg alcohol concentration to 80% of ethanol, stirred evenly, and sealed and soaked for 6 days to obtain the soaking solution. The soaking solution was percolated through the percolation tank with a flow rate of 4ml per minute. The percolation solution was collected and filtered. The filtrate was recovered at -0.07MPa and 80°C. , vacuum concentrated into an extract with a relative density of 1.20 at 80°C, and absorb the macroporous resin on the extra...

Embodiment 2

[0084] The specific preparation of embodiment 2 oral liquid 2

[0085]29g of Evodia rutaecarpa, 26g of flying grass, 84g of Atractylodes macrocephala, 31g of citrus aurantium, 58g of gall, 33g of black plum, 27g of red cardamom, 38g of Tibetan calamus, 27g of pine pollen, 54g of white lentils, 37g of licorice, 35g of lotus seeds, 46g of psoraleae, catechin 20g, Mingdangshen 40g, Fangfeng 44g, Betel nut 26g, Bergamot 33g, Agarwood 28g, Coix seed 34g, Lithium japonica 27g, Galangal 33g, Coptis 40g, Toon bark 34g, Golden fruit olive 23g, add 75kg alcohol concentration to 80% of ethanol, stirred evenly, and sealed and soaked for 6 days to obtain the soaking solution. The soaking solution was percolated through the percolation tank with a flow rate of 5ml per minute. The percolation solution was collected and filtered. The filtrate was recovered at -0.07MPa and 80°C. , vacuum concentrated into an extract with a relative density of 1.20 at 80°C, and absorb the macroporous resin on t...

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Abstract

The invention provides a traditional Chinese medicine composition for treating a diarrhea-dominant irritable bowel syndrome. The traditional Chinese medicine composition comprises fructus evodiae, hairy euphorbia, bighead atractylodes rhizome, immature bitter orange, gallnut, smoked plum, fructus galangae, acorus calamus L., pollen pini, white hyacinth bean, liquorice, lotus seeds, fructus psoraleae, catechu, changium smyrnioides, radix saposhnikoviae, betel nuts, fingered citron, agilawood, semen coicis, polygonum aviculare, rhizoma alpiniae officinarum, coptis roots, cortex ailanthi and radix tinosporae. Compared with western medicine for treatment, the composition has the advantages that the composition is good in curative effect, takes effect rapidly, has no toxic or side effects, does not result in tolerance, and can effectively relieve illness of a patient, and the recurrence rate is low.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating diarrhea-type irritable bowel syndrome and a preparation method thereof. Background technique [0002] Irritable bowel syndrome (IBS) is a common gastrointestinal disorder in clinical practice. Onset, but lack of morphological and biochemical abnormalities and other clinical symptoms that can be explained by organic diseases. The Rome III subtype classification standard divides it into diarrhea type (IBS-D), constipation type (IBS-C), mixed type (IBS-M) and indeterminate type (IBS-U). The prevalence rate of this disease is 10%~20% in European and American countries, and the prevalence rate in cities in my country is about 10.5%. Diarrhea-type irritable bowel syndrome is the main disease, which seriously affects the quality of life of patients. The society and the family have caused a huge economic and s...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P1/12A61K35/64
Inventor 侯磊磊
Owner 刘俊
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