Application of astaxanthin in preparing medicine for preventing embryotoxicity caused by organophosphorus pesticide

Abstract

The invention relates to a medicine novel application of astaxanthin, namely the effect of preventing and treating embryotoxicity caused by organophosphorus pesticide and the effects of inhibiting reduction of embryo live rate, rising of embryo still birth rate or embryo absorption rate and the reduction of placenta weight, which are caused by the organophosphorus pesticide. A pharmacological test verifies that the astaxanthin can effectively inhibit pregnant rat live embryo quantity, the reduction of the embryo live rate, the rising of the still birth rate or the embryo absorption rate, and the reduction of the weight, the body length, the tail length and the placenta weight of live fetal rats, which are caused by the organophosphorus pesticide (moncrotophos and phoxim); and the astaxanthin can inhibit the embryotoxicity caused by the organophosphorus pesticide and has the effective dosage dependence. The astaxanthin has the good inhibition effect on the embryotoxicity caused by the organophosphorus pesticide, can be used for preparing a medicine of the embryotoxicity caused by the organophosphorus pesticide, and can also be used for preparing a medicine for preventing and treating diseases induced by the embryotoxicity caused by the organophosphorus pesticide.

Description

technical field [0001] The invention relates to the application of astaxanthin, in particular to the application of astaxanthin in the preparation of medicines for preventing and treating embryotoxic diseases caused by organophosphorus pesticides. Background technique [0002] Organophosphorus pesticides (OPs) are a class of high-efficiency and low-residue pesticides, which have become the broadest-spectrum pesticides used in China today. The use of organophosphorus pesticides has made great contributions to the increase of production and harvest in agriculture, forestry, and fishery. However, with the widespread use of organophosphorus pesticides, their residues in vegetables and fruits are also more common. Although most people have paid attention to the prevention of acute poisoning of organophosphorus pesticides, the impact of long-term, low-dose, and chronic exposure of organophosphorus pesticides on human health, especially the impact of pregnant women on offspring, ha...

AI Technical Summary

Problems solved by technology

Although most people have paid attention to the prevention of acute poisoning of organophosphorus pesticides, the impact of long-term, low-dose, and chronic

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