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Rapid imaging method of blood vessel without contrast agent

An imaging method and contrast agent technology, applied in the field of medical imaging, can solve problems such as inability to directly apply vascular imaging, and achieve the effect of reducing signal instability

Active Publication Date: 2014-12-17
SHANGHAI UNITED IMAGING HEALTHCARE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the current k-space parallel accelerated imaging method cannot be directly applied to blood vessel imaging with N / 2 ghost images
[0010] The present invention overcomes the defect that the k-space parallel accelerated imaging method in the prior art cannot be directly applied to blood vessel imaging of N / 2 ghosts, and proposes a fast blood vessel imaging method without contrast agent, aiming at N / 2 ghost imaging, Redesign the sampling design and data processing process of the k-space parallel accelerated imaging method, improve the existing k-space parallel accelerated imaging method and data processing flow, and combine and apply the k-space parallel accelerated imaging method with N / 2 ghost imaging contrast agent-free angiography

Method used

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  • Rapid imaging method of blood vessel without contrast agent
  • Rapid imaging method of blood vessel without contrast agent

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Experimental program
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Effect test

Embodiment 1

[0051] (1) Two sampling conditions m1 and m2 of different blood flow states are determined by using two different trigger delay times of cardiac gating, and two blood flow signals M1 and M2 are obtained by sampling respectively. Wherein, the blood flow signals M1 and M2 are signals collected under the sampling conditions m1 and m2 respectively. Such as Figure 7 As shown, for example, a trigger delay time d1=0.1 second and d2=0.5 is used.

[0052] (2) Carry out k-space parallel accelerated processing on the k-space under the two sampling conditions m1 and m2, and combine the two k-spaces after parallel accelerated processing according to the N / 2 ghost imaging technology to obtain a summed accelerated k-space ,Such as figure 2 As shown, for example, the acceleration factor R=3 is adopted for the complete k-space of 256 lines, all 31 lines are taken in the central area, and one line is taken every three lines in the peripheral high-frequency area. Two accelerated k-spaces wi...

Embodiment 2

[0060] (1) Under the same ECG gating condition, two different flow-compensated signals are used in the imaging sequence, and two imaging sequences with different sensitivities to the blood flow state are used to obtain two different sampling conditions of m1 and m2 , two blood flow signals M1 and M2 corresponding to the two sampling conditions of m1 and m2 are obtained by sampling, such as Figure 8 shown.

[0061] (2) Carry out k-space parallel accelerated processing on the k-space under the two sampling conditions m1 and m2, and combine the two k-spaces after parallel accelerated processing according to the N / 2 ghost imaging technology to obtain a summed accelerated k-space . Such as figure 2 As shown, for example, the acceleration factor R=3 is used for the complete k-space of 256 lines, all 31 lines are taken in the central area, and one line is taken for every three lines in the peripheral high-frequency area, and two accelerated k-spaces with 106 lines are obtained, w...

Embodiment 3

[0069] (1) Under the same cardiac gating trigger condition, the magnetic reversal of the upstream or downstream protons in the imaging area is realized. For example, a 180-degree adiabatic radio frequency pulse is used to realize the magnetic reversal, and two different sampling conditions of m1 and m2 are obtained. The sampling results are respectively related to m1, The two blood flow signals M1 and M2 corresponding to the two sampling conditions of m2, such as Figure 9 shown.

[0070] (2) Carry out k-space parallel accelerated processing on the k-space under the two sampling conditions m1 and m2, and combine the two k-spaces after parallel accelerated processing according to the N / 2 ghost imaging technology to obtain a summed accelerated k-space ,Such as figure 2 shown. For example, the acceleration factor R=3 is used for the complete k-space of 256 lines, all 31 lines are taken in the central area, and one line is taken for every three lines in the peripheral high-freq...

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Abstract

The invention discloses a parallel accelerating imaging method of a blood vessel without contrast agent. The rapid imaging method of the blood vessel without contrast agent includes the following steps: obtaining two different blood flow signal sampling conditions through two different blood fluid signals, conducting a parallel acceleration process on the two different blood flow signal sampling conditions in a k space to obtain two k spaces, combining the two k spaces to obtain an additive acceleration k space, sampling in the additive acceleration k space to obtain k space sampling signals, dividing the k space sampling signals into two groups and respectively processing each group of the k space sampling signals, combining the two groups of k space sampling signals into complete additive k space data, transforming the complete additive k space data to obtain images and extracting the images to obtain images of the blood vessel. The rapid imaging method of the blood vessel without contrast agent improves the present k space parallel acceleration imaging method and data process technological process and enables the k space parallel acceleration imaging method to be combined with an N / 2 ghost imaging and to be applied to the blood flow imaging of the blood vessel without contrast agent.

Description

technical field [0001] The invention belongs to the field of medical imaging, and in particular relates to a method for fast imaging of blood vessels without a contrast agent. Background technique [0002] Conventional magnetic resonance angiography generally requires the use of contrast agents, such as GdDTPA, to shorten the T1 time of water protons in blood vessels to help increase the contrast between blood signals and background signals. However, since the nephrogenic systemic fibrosis (NSF) induced by contrast agents has received a lot of attention in recent years, contrast agent-free angiography has been more widely valued and researched and developed. [0003] Most contrast agent-free angiography techniques are based on blood flow characteristics, which correlate magnetic resonance signals with blood flow status. For example, by acquiring two magnetic resonance signals of different blood flow states, blood vessel imaging can be realized from the difference between th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/026
Inventor 张卫国
Owner SHANGHAI UNITED IMAGING HEALTHCARE