Soft capsule for treating nerve diseases

A technology of soft capsules and soft capsule shells, applied in nervous system diseases, capsule delivery, blood diseases, etc., can solve problems such as left ventricular enlargement and reduction, improve subjective symptoms, improve brain energy metabolism, and inhibit the production of lipid peroxides qualitative effect

Active Publication Date: 2013-04-24
DALIAN JINSHITAN PHARMA
View PDF3 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Idebenone prevented iron-induced lipid peroxidation and myocardial injury in three patients given 5 mg / kg daily for 4-9 months, resulting in a reduction in left ventricular enlargement in these patients

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Soft capsule for treating nerve diseases
  • Soft capsule for treating nerve diseases
  • Soft capsule for treating nerve diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Embodiment 1: prepare soft capsule of the present invention

[0060] Liquid formula:

[0061] Idebenone:

6g

Soybean oil: appropriate amount, add to

100g

[0062] Softgel Shell Formulation:

[0063] Gelatin:

100g

Glycerin:

50g

water:

100g

[0064] Preparation steps:

[0065] (1) Preparation of medicinal solution: prepare idebenone and auxiliary materials into medicinal solution at room temperature;

[0066] (2) Preparation of soft capsule shell material: mixing and dissolving gelatin, plasticizer, and water to make a soft capsule shell material liquid;

[0067](3) Preparation of soft capsules: use the dropping method, the content weight of each capsule is 500mg (those skilled in the art can easily adjust and control the content within the scope of 200mg~2000mg / granule, such as controlling to about 250mg, about 500mg, about 750mg, about 1000mg, about 1500mg, etc. Or control the amount of activ...

Embodiment 2

[0069] Embodiment 2: prepare soft capsule of the present invention

[0070] Liquid formula:

[0071] Idebenone:

[0072] Softgel Shell Formulation:

[0073] Gelatin:

[0074] Preparation steps: carry out with reference to the method of Example 1.

Embodiment 3

[0075] Embodiment 3: prepare soft capsule of the present invention

[0076] Liquid formula:

[0077] Idebenone:

[0078] Softgel Shell Formulation:

[0079] Gelatin:

[0080] Preparation steps: carry out with reference to the method of Example 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a soft capsule for treating nerve diseases. The soft capsule comprises a liquid medicine and a soft capsule casing for sealing the liquid medicine, wherein the liquid medicine contains active ingredients. The medicine composition of the soft capsule is the only medicine which achieves double improvements on brain metabolism and psychiatric symptoms and has no direct competitor at present; and the soft capsule is a brain metabolism improver and cranial nerve cell protective agent, can prevent mitochondrial diseases, inhibit platelet aggregation and improve microcirculation effectively, has an effective antioxidation function, and is also a preferred medicine for treating FRDA (Friedreich ataxia). The successful development of the soft capsule can provide enormous economic and social benefits for the pharmacy industry.

Description

technical field [0001] The invention relates to a soft capsule for treating neurological diseases. Background technique [0002] Neuronal damage, neurodegenerative diseases and syndromes (Alzheimer's disease, multiple sclerosis, Friedrich's ataxia, brain and spinal cord injuries and neurotrauma, stroke, Parkinson's disease, alcoholism and narcolepsy, postoperative recovery syndrome and postanesthesia recovery syndrome) and many other conditions require effective treatment and prevention. [0003] Postoperative stroke and cognitive deficit (POSCD) syndrome is common, especially in older adults undergoing major surgical procedures such as heart surgery or hip replacement. In North America, more than 2.5 million such surgical procedures are performed each year, and the incidence of POSCD exceeds 30%. There is an urgent need for interventional therapy, and there are not enough treatment options for this distressing postoperative condition. In the United States, more than 2 mi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K31/122A61P9/00A61P25/00A61P25/18A61P9/10A61P25/22A61P25/24A61P7/02A61P39/06A61P25/28
Inventor 刘炜
Owner DALIAN JINSHITAN PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap