Medical water-based lubricant for introducing instrument into body cavity

A water-based lubricant and equipment technology, which is used in medical science, surgery and other directions to achieve the effects of good lubricity, good use effect and safety, and comfortable use.

Inactive Publication Date: 2013-05-08
BLOOMAGE BIOTECHNOLOGY CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to solve the problems of poor lubricating performance and difficult removal of residues in the lubricants used in traditional Chinese medicine body cavity instruments in the prior art, the present invention provides a bio- High compatibility, wide application range, safe and reliable water-based lubricant for medical body cavity instruments

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Take 971.5g of purified water at a constant temperature of 50°C, dissolve 1.7g of sodium methylparaben, 0.6g of sodium propylparaben and 1.2g of citric acid in purified water, add 10g of glycerin and stir until completely dissolved, then slowly add 15g of transparent Sodium Hyaluronate ( Mr 0.33×10 6 ), fully stirred until completely dissolved, filtered through a 10μm filter membrane, sterilized by steam and cooled to room temperature.

[0029] The prepared lubricant has a dynamic friction coefficient μ=0.050 and a dynamic viscosity of 5500 mPa·s.

Embodiment 2

[0031] Take 909g of purified water at a constant temperature of 50°C, dissolve 1.7g of sodium methylparaben, 0.3g of sodium ethylparaben and 1g of citric acid in purified water, add 80g of glycerin and stir until completely dissolved, then slowly add 8g of hyaluronic acid sodium( Mr 1.73×10 6 ), fully stirred until completely dissolved, filtered through a 10μm filter membrane, sterilized by steam and cooled to room temperature.

[0032] The prepared lubricant has a dynamic friction coefficient μ=0.053 and a dynamic viscosity of 6600 mPa·s.

Embodiment 3

[0034] Take 918.3g of purified water at a constant temperature of 50°C, dissolve 5g of potassium sorbate and 1.7g of sodium bicarbonate in purified water, add 70g of propylene glycol and stir until completely dissolved, then slowly add 5g of sodium hyaluronate ( Mr 2.67×10 6 ), fully stirred until completely dissolved, filtered through a 10μm filter membrane, sterilized by steam and cooled to room temperature.

[0035] The prepared lubricant has a dynamic friction coefficient μ=0.059 and a dynamic viscosity of 5250 mPa·s.

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PUM

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Abstract

The invention relates to the technical field of medical reagents and in particular relates to a medical water-based lubricant for introducing an instrument into a body cavity. The medical water-based lubricant comprises the following components in percentage by mass: 0.5-1.5% of lubricating and thickening components and 1-10% of an excipient, wherein the pH value is 5 to 7. Compared with a common lubricant, the medical water-based lubricant has better lubricating property and good biocompatibility and can be used more comfortably and naturally; and a relatively mild preservative is adopted, so that the medical water-based lubricant has a better using effect, better safety and a wide application range, and does not have any adverse reaction. When the medical water-based lubricant is used for clinical diagnosis and treatment, the medical water-based lubricant is smeared in an orifice and on the surface of the instrument to ensure that the friction force between the instrument and mucous membranes of the orifice can be greatly reduced, and the damage to tissues caused by the instrument is alleviated. The medical water-based lubricant can be widely used for lubricating an instrument such as a conduit, an endoscope or a dilator to be inserted into the respiratory tract, the digestive tract, the urethra, the vagina, the rectum and the anus.

Description

Technical field [0001] The invention involves the field of medical reagent technology, and specially involves a water -based lubricant of medical body cavity instruments. Background technique [0002] With the advancement of medical levels, the application of endoscope and intubation technology has extended to different fields of clinical diagnosis and treatment, and is positioned in different parts such as human respiratory tract, digestive tract, urethra, vagina, rectum, and anus.Because such medical devices will cause different degrees of mechanical damage to the cavity mucosa when entering the human cavity, and bring discomfort and pain to patients. Therefore, in clinical useWith an appropriate amount of lubricant to reduce the damage of the instrumental mucosa and reduce the patient's pain and discomfort. [0003] At present, oily substances such as mineral oil, organic silicon, and vegetable oil are mainly used as the main component of medical lubricants.For example, China...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/04A61L31/14
Inventor 郭学平宋永民栾贻宏丁厚强石艳丽耿凤
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
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