Forensic medicine compound detection kit based on Y chromosome SNP (single nucleotide polymorphism) genetic marker

A genetic marker, Y chromosome technology, applied in the field of forensic genetics, can solve the problems of difficult selection of Y chromosome SNP genetic markers, limited number of Y-SNPs, and no Y-SNP composite detection system, and achieves widespread promotion and application value. , accurate typing, high-efficiency effect
CN103131787BActive Publication Date: 2014-05-21SICHUAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SICHUAN UNIV
Publication Date
2014-05-21

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Abstract

The invention belongs to the field of forensic medicine genetics and in particular relates to a forensic medicine compound detection kit based on a Y chromosome SNP (single nucleotide polymorphism) genetic marker for individual recognition and genetic relationship identification by a legal medical expert. The forensic medicine compound detection kit provided by the invention is used for carrying out forensic medicine genetic relationship identification and individual recognition on human biology detection materials by utilizing a Y chromosome SNP genetic marker. According to the technical scheme for solving the technical problem, the forensic medicine compound detection kit based on the Y chromosome SNP genetic marker comprises a separated and packaged compound amplification primer mixture, a multiple single-basic-group extension reaction primer mixture, an allele typing standard mixture, a compound amplification reaction mixture and a single-basic-group extension reaction mixture. The kit provided by the invention can be applied to detection of common degradable materials in forensic medicine.
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Description

technical field

[0001] The invention belongs to the field of forensic genetics, in particular to a forensic compound detection kit based on Y chromosome SNP genetic markers for forensic individual identification and kinship identification. Background technique

[0002] Single Nucleotide Polymorphism (SNP) is a DNA sequence polymorphism caused by a single base variation at a specific nucleotide position in the genome, and is the most common and widely distributed type of DNA polymorphism in the human genome . SNPs are mostly biallelic genetic markers, which have the characteristics of genetic stability, low mutation rate, small amplification fragments, easy automation, and high-throughput analysis.

[0003] The human Y chromosome is the sex-determining chromosome unique to males. Due to the different ways of inheritance, the Y chromosome can be divided into two regions, one is the pseudo-autosomal region located at both ends of the Y chromosome, and the other is the Y-speci...

Claims

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