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Pulse-invigorating capsule for treating carotid artery atherosclerosis as well as preventing and treating ischemic cerebral apoplexy

A technology for atherosclerosis and ischemic stroke, which can be applied to cardiovascular system diseases, medical preparations containing active ingredients, plant raw materials, etc., and can solve problems that affect long-term efficacy and unclear pathological mechanisms

Inactive Publication Date: 2013-06-26
王永刚 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the problem of restenosis affects the long-term efficacy and is the final result of a series of complicated related events, the pathological mechanism is not very clear, and the currently used aspirin and statin lipid-lowering drugs are not satisfactory to try to change or control this process

Method used

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  • Pulse-invigorating capsule for treating carotid artery atherosclerosis as well as preventing and treating ischemic cerebral apoplexy
  • Pulse-invigorating capsule for treating carotid artery atherosclerosis as well as preventing and treating ischemic cerebral apoplexy
  • Pulse-invigorating capsule for treating carotid artery atherosclerosis as well as preventing and treating ischemic cerebral apoplexy

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Experimental program
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Embodiment Construction

[0062] Firstly, each composition in the formula of Tongmai Capsules for treating carotid atherosclerosis and preventing ischemic cerebral apoplexy is Danshen: Coptidis: Radix Puerariae: Panax notoginseng=55%: 20%: 15%: 10%. Proportional reclaiming.

[0063] The four traditional Chinese medicines in the Tongmai Capsule formula for treating carotid atherosclerosis and preventing ischemic stroke were purified and processed according to the processing methods of each traditional Chinese medicine in the first volume of the Pharmacopoeia of the People's Republic of China in 2010. Dry at low temperature for 2 hours for later use. Among them, the three traditional Chinese medicines of salvia miltiorrhiza, berberine, and kudzu root are mixed and pulverized into fine powder, passed through a 100-mesh sieve, and set aside. Mix notoginseng, dry and pulverize it into medium powder, pass through an 80-mesh sieve, mix with the above-mentioned 3 herbs in equal increments, and weigh them for ...

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Abstract

The invention provides a pulse-invigorating capsule for treating carotid artery atherosclerosis as well as preventing and treating ischemic cerebral apoplexy, which is composed of red sage root, coptis, root of kudzu vine and pseudo-ginseng with weight percentage of 50-55%: 15-20%: 15-20%: 5-10%. The pulse-invigorating capsule for treating carotid artery atherosclerosis as well as preventing and treating ischemic cerebral apoplexy has the characteristics of multiple targets and multiple approaches, and has integration and regulation effects with multiple targets on atherosclerotic plaque. The pulse-invigorating capsule can inhibit the formation of neointima through antithrombosis, anti inflammatory, endothelial cells injury restoration, lipid lowering, microcirculation improvement, blood vessel smooth muscle cell propagation inhibition and the like, the antiatherosclerosis effect can be performed, and the pulse-invigorating capsule can promote the restoration of tissue of the operation blood vessel wound, can prevent several phases of a restenosis process at an early stage after a CEA operation, and the several phases comprise a thrombus formation phase, an inflammation reaction phase, an endothelial restoration phase, a blood vessel smooth muscle propagation phase, a matrix formation phase and the like.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for treating carotid atherosclerosis and preventing and treating iron-deficiency cerebral apoplexy, which is a Tongmai capsule for treating carotid atherosclerosis and preventing and preventing ischemic cerebral apoplexy. Background technique [0002] Stroke is a common and frequently-occurring disease that endangers human life and health. It has the characteristics of high morbidity, high mortality, high disability rate, and high recurrence rate. It ranks the third cause of human death and the first cause of disability. . In my country, there are about 2 million new patients every year, more than 1.5 million deaths, about 75% of the survivors are disabled, and the recurrence rate within 5 years is as high as 41%. The existing patients in the country are 6-7 million. Among them, hemorrhagic disease accounted for 29.3%, ischemic disease accounted for 62.4%, unknown accounted for 8.3%, and the annu...

Claims

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Application Information

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IPC IPC(8): A61K36/718A61P9/10
Inventor 王永刚郑刚齐婧周晓俊
Owner 王永刚
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