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Centella total glycoside cataplasm and preparation method thereof

A technology of centella asiatica and prescription, which is applied in the field of total glycosides of centella asiatica cataplasm and its preparation, which can solve the problems of small drug loading of ointment, influence of production process on the environment, and pollution of clothes, so as to reduce the frequency of medication, Easy to use, no pollution to clothes

Inactive Publication Date: 2013-10-23
上海卫生材料厂有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At the same time, the existing ointment has little drug loading, is inconvenient to use, pollutes clothes, and the manufacturing process affects the environment.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0035] On the other hand, the preparation method of the asiaticoside cataplasm of the present invention, it comprises the steps:

[0036] (1) Weigh tartaric acid according to the prescription, add purified water, stir and dissolve to obtain 1 # Intermediate;

[0037] (2) Weigh the gelatin according to the prescription, add purified water, heat to 55-65°C, make the gelatin swell until transparent and keep it warm to get 2 # Intermediate;

[0038] (3) Weigh titanium dioxide according to the prescription, add purified water, stir and mix to obtain 3 # Intermediate;

[0039] (4) Weigh PVP according to the prescription, add purified water, and swell to obtain 4 # Intermediate;

[0040] (5) Weigh β-cyclodextrin according to the prescription, add purified water, stir for 30 minutes, slowly add asiaticoside powder, and stir; when the mixture thickens slightly, add 3 # intermediate, 2 # Intermediate and 4 # Intermediate, stirred until homogeneous to obtain 5 # Intermediate;

...

Embodiment 1

[0048] Components:

[0049] Sodium polyacrylate 5.0%, gelatin 0.5%, sorbitol 7.0%, PVP (polyvinylpyrrolidone) 1.5%, glycerin 20.0%, titanium dioxide 0.3%, β-cyclodextrin 2.0%, tartaric acid 0.15%, asiaticoside powder 2.0% , aluminum glycylate 0.05% and purified water 61.5%.

[0050] Weigh tartaric acid according to the prescription, add purified water, stir and dissolve to obtain 1 # Intermediate;

[0051] Weigh the gelatin according to the prescription, add purified water, heat to 55°C, make the gelatin swell until transparent and keep it warm to obtain 2 # Intermediate;

[0052] Weigh titanium dioxide according to the prescription, add purified water, stir and mix to obtain 3 # Intermediate;

[0053] Weigh PVP according to the prescription, add purified water, and swell to obtain 4 # Intermediate;

[0054] Weigh β-cyclodextrin according to the prescription, add purified water, stir for 30 minutes, slowly add asiaticoside powder, and stir; when the mixture thickens sli...

Embodiment 2

[0061] Components:

[0062] Sodium polyacrylate 6.5%, gelatin 0.65%, sorbitol 8.5%, PVP (polyvinylpyrrolidone) 2.0%, glycerin 30.0%, titanium dioxide 0.45%, β-cyclodextrin 3.0%, tartaric acid 0.28%, asiaticoside powder 3.5% , 0.15% aluminum glycylate and 44.97% purified water.

[0063] Weigh tartaric acid according to the prescription, add purified water, stir and dissolve to obtain 1 # Intermediate;

[0064] Weigh the gelatin according to the prescription, add purified water, heat to 60°C, make the gelatin swell until transparent and keep it warm to obtain 2 # Intermediate;

[0065] Weigh titanium dioxide according to the prescription, add purified water, stir and mix to obtain 3 # Intermediate;

[0066] Weigh PVP according to the prescription, add purified water, and swell to obtain 4 # Intermediate;

[0067] Weigh β-cyclodextrin according to the prescription, add purified water, stir for 30 minutes, slowly add asiaticoside powder, and stir; when the mixture thickens ...

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Abstract

The invention aims to disclose centella total glycoside cataplasm and a preparation method thereof. The centella total glycoside cataplasm comprises the following components in percentage by weight: 5.0%-8.0% of sodium polyacrylate, 0.5%-0.8% of gelatin, 7.0%-10.0% of sorbitol, 1.5%-2.5% of PVP (polyvinylpyrrolidone), 20.0%-40.0% of glycerinum, 0.3%-0.6% of titanium dioxide, 2.0%-4.0% of beta-cyclodextrin, 0.15%-0.4% of tartaric acid, 2.0%-5.0% of centella glycoside powder, 0.05%-0.25% of dihydroxyaluminium aminoacetate and 61.5%-28.45% of purified water. Compared with the prior art, the centella total glycoside cataplasm has the characteristics of being large in drug loading capacity, convenient to use, etc, overcomes the inconvenience caused by pollution to clothes in use, and is suitable for treating trauma, operative wound, burn, keloid and scleroderma, therefore, the aim of the invention is realized.

Description

technical field [0001] The invention relates to a medicine and a preparation method thereof, in particular to an asiaticoside cataplasm suitable for treating trauma, surgical trauma, burns, keloids and scleroderma and a preparation method thereof. Background technique [0002] "Scar" is the damage of physical, biological and chemical factors on the human skin and soft tissue, resulting in serious damage to the skin and soft tissue, which cannot be fully repaired by itself, and is replaced by fibrous tissue. Local symptoms that affect both appearance and function . What "scars" bring to patients is huge physical pain and mental pain, especially the scars left over from burns, scalds, and severe trauma. The several years of scar hyperplasia almost made the patient miserable. Then the atrophy period makes the patient's face unrecognizable and dysfunction, causing the patient's great physical and mental obstacles. [0003] Excessive collagen deposition is one of the main caus...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K36/23A61K47/42A61P17/02A61P17/00
Inventor 田露叶承范王滨
Owner 上海卫生材料厂有限公司
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