Natural pharmaceutical composition and preparation method

A technology of natural medicines and compositions, which is used in drug combinations, pharmaceutical formulations, antitumor drugs, etc.

Inactive Publication Date: 2013-11-13
石强
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural pharmaceutical composition and preparation method

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Effect test

Embodiment approach

[0031] The first step: preparation of various extracts

[0032] (1) Preparation of cinnamon chebula decoction concentrated extract

[0033] Take cinnamon and myrobalan according to the compatibility ratio of 1-4:1, soak in distilled water, heat and decoct for 1 hour, filter, add distilled water to the medicine dregs, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and Membrane filtration, drying under reduced pressure, that is.

[0034] (2) Preparation of cinnamaldehyde

[0035] Grind cinnamon, weigh cinnamon bark powder, heat and extract with 95% ethanol in a Soxhlet extractor, filter, recover ethanol under reduced pressure, conduct steam distillation, add NaCl to the distillate, extract with diethyl ether three times, combine diethyl ether Add an appropriate amount of anhydrous calcium chloride desiccant to the extract, dry it for 30 minutes, remove the desiccant, recover ether, and then use vacuum distillation to collect fractions at...

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Abstract

The invention relates to a natural pharmaceutical composition and a preparation method. The natural pharmaceutical composition comprises 1, water-decoction condensation extract of cinnamon and myrobalan, 2, cinnamyl aldehyde and 3, 70% ethanol extract of myrobalan according to a ratio of 7-8: 4-7: 2-5. The natural pharmaceutical composition has very good effects on cancer chemotherapy-related diarrhoea and can produce synergism with cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is made up of cinnamon chebula decoction concentrated extract, cinnamaldehyde and chebula 70% ethanol extract, the preparation of this natural medicine composition The method and the use of the natural medicine composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61P35/00A61P1/12A61K31/11
Inventor 石强
Owner 石强
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