TCM composition for treatment of seborrheic alopecia and alopecia areata and preparation method of TCM composition

A technology for seborrheic alopecia and composition, which is applied in directions such as drug combination, medical formula, medical preparation containing active ingredients, etc., can solve problems such as unsatisfactory effect of traditional Chinese medicine composition

Active Publication Date: 2013-11-27
杨凌步长制药有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Because of this, an invention patent has been applied for this Chinese medicine composition, its publication number is CN1343516A, and the publication date is April 10, 2002. However, in the actual clinical application process, we found that the effect of the traditional Chinese medicine composition made by the above preparation method is not ideal, and the patent application is to further optimize the preparation process through a large number of experiments, and find a more The best preparation process and parameters have been proved by clinical trials to be more effective. Therefore, we have successfully developed a traditional Chinese medicine combination for the treatment of seborrheic alopecia and alopecia areata for the purpose of improving the stability and bioavailability of the preparation. thing

Method used

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  • TCM composition for treatment of seborrheic alopecia and alopecia areata and preparation method of TCM composition
  • TCM composition for treatment of seborrheic alopecia and alopecia areata and preparation method of TCM composition
  • TCM composition for treatment of seborrheic alopecia and alopecia areata and preparation method of TCM composition

Examples

Experimental program
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Effect test

Embodiment 1

[0063] Get the prescription proportioning composition of above-mentioned a prescription, and operate according to the following preparation method:

[0064] ⑴ Grind Polygonum multiflorum, Chinese yam, and Poria cocos into coarse powder, and then ultrafinely pulverize into medicinal powder of less than 100 μm for later use;

[0065] ⑵ Take Eclipta, Cornus officinalis, Codonopsis pilosula, Anemarrhena, Alisma, and ginseng, add 70% ethanol with a weight ratio of 9 times the medicinal materials, reflux extraction twice, each time for 2 hours, filter, combine the filtrate and recover the ethanol until it is free of alcohol After flavoring, the medicinal solution is concentrated and dried, and crushed into a dry paste powder, sieved, and the medicinal residue is used for later use;

[0066] (3) Take leaves of oriental cypress, peony cortex, and silver bupleurum, add water with a weight ratio of 10 times that of medicinal materials, steam distillation for 1 hour, collect volatile oil...

Embodiment 2

[0070] Take the medicinal materials in the weight ratio described in the above prescription b, and prepare according to the preparation method of "Example 1".

Embodiment 3

[0072] Take the medicinal materials in the weight ratio described in the above prescription c, and prepare according to the preparation method of "Example 1".

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PUM

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Abstract

The invention relates to a TCM composition for treatment of seborrheic alopecia and alopecia areata and a preparation method of the TCM composition. The TCM composition comprises the following raw materials in parts by weight: 282-424 parts of radix polygonum multiflorum preparata, 253-332 parts of herba ecliptae, 229-343 parts of cacumen biotae, 117-175 parts of prepared rehmannia root, 106-158 parts of dried rehmannia root, 51-77 parts of dogwood, 46-69 parts of Chinese yam , 42-62 parts of ginseng, 37-55 parts of radix codonopsitis, 28-42 parts of Indian buead, 17-25 parts of tree peony bark, 26-38 parts of alisma, 19-28 parts of rhizoma anemarrhenae, 14-22 parts of cortex lycii radicis and 13-19 parts of radices stellariae dichotomae. The TCM composition is TCM oral liquid prepared by the steps of extracting and purifying the raw materials according to a certain technique and adding pharmaceutically acceptable auxiliary materials. According to the invention, the TCM oral liquid has the characteristics of simple and feasible preparation technology, safety, effectiveness, obvious pharmacological effect and remarkable clinical effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating seborrheic alopecia and alopecia areata and a preparation method thereof, belonging to the technical field of pharmaceutical preparations. Background technique [0002] Seborrheic alopecia is called "white dandruff wind" in traditional Chinese medicine, and also known as male pattern baldness in western medicine, androgenetic alopecia, diffuse alopecia, which is a baldness that progresses slowly on the forehead, temporal, and top after puberty, and can be used by both sexes Occurs, but is more common in male patients. It is also a common and frequently-occurring disease in dermatology clinics, and it is also one of the refractory diseases. Modern medicine thinks that the occurrence of this disease is related to imbalance of sex hormones and excessive secretion of sebaceous glands. Clinically, patients with this disease are often accompanied by more seborrhea on the head,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61P17/14
Inventor 赵步长
Owner 杨凌步长制药有限公司
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