Microfluidic Chip Combiner

Abstract

The invention discloses a micro-fluidic chip laminating machine which comprises a base, a solidification device, a positioning disk, a vacuum pressurization device and a control mechanism, wherein the solidification device is installed in the slotted hole in the top of the base, the solidification device comprises an ultraviolet curing lamp which is fixed to the inner bottom of the slotted hole, and an automatic door is arranged between side walls of the slotted hole above the ultraviolet curing lamp; the positioning disk is fixed to the top of the base, the positioning disk comprises a disk surface corresponding to the slotted hole in dimension, a side tank with a vacuum absorption hole in the inner side is formed in the periphery of the disk surface, and block pieces for horizontal motion separation and controlled by an air cylinder are arranged on corners of the side tank; the vacuum pressurization device is arranged over the positioning disk and comprises a vacuum chamber of an externally-arranged vacuum pump, the vacuum chamber is driven by a servo motor A and matched with the outer edge of the top of the slotted hole, and a vacuum cavity driven by a servo motor B and corresponding to the disk surface on the inner side of the side tank is arranged in the vacuum chamber. The micro-fluidic chip laminating machine has the advantages of being high in automation degree and efficiency, low in cost, free of bubbles after bonding, and high in bonding strength.

Description

technical field [0001] The invention relates to a mechanical device for manufacturing a microfluidic chip, in particular to a mechanical device used for the lamination process of large-area hard materials in the microfluidic chip. Background technique [0002] An integrated microfluidic chip can be prepared by using microfluidic chip technology and high-throughput gene chip technology. Through highly integrated and automated technology, the assay work of the entire laboratory can be completed on this chip. Using a microfluidic chip can detect 500 kinds of non-cultured microorganisms at one time. Compared with traditional culture technology, it has the characteristics of large detection throughput, fast detection speed, high degree of automation, and easy operation. Good tool for research. [0003] The measurement unit for the preparation of microfluidic chips is calculated in microns, and the manufacturing precision is required to be high. And it usually involves two diff...

AI Technical Summary

Problems solved by technology

However, due to the large area and hard material of the combined double plates (ie, the base plate and the cover plate), the conventional combination process is not sufficient to remove the bubbles before the combination, and there are air bubbles between the cover plate and the base plate, because the pressure is not appropriate during the combination. Or the bonding glue is not well solidified, resulting in poor bonding strength, which cannot completely bond the cover plate and the substrate

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