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Compound traditional Chinese medicine acne gel and preparation method thereof

A technology of compound traditional Chinese medicine and gel, which is applied in acne skin care products, medicines for treating acne and oily skin. It can solve problems such as being easily affected by sweat, dependence on drug resistance, and insufficient adhesion, and achieve the elimination of pigmentation. , Strong water solubility, easy to carry effect

Active Publication Date: 2014-01-22
上海一非医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Now the dosage forms for external use of acne include ointment, cream, lotion, liniment, etc. These dosage forms have certain deficiencies in the treatment of acne, such as ointment and cream themselves contain oily ingredients, which are not suitable for the treatment of acne with strong sebaceous gland secretion. There is a certain impact; while lotion, liniment and other drugs have insufficient adhesion and are easily affected by sweat
In addition, the use of Western medicine acne ointment treatment will produce problems such as drug resistance and dependence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Example 1: 10 parts of Salvia miltiorrhiza, 15 parts of Scutellaria baicalensis, 15 parts of Hedyotis diffusa, 25 parts of wild chrysanthemum, 15 parts of safflower, 20 parts of Baiwei, 15 parts of licorice, 10 parts of carbomer 934PNF, 10 parts of triethanolamine, glycerin 20 parts, 50 parts of propylene glycol, 0.5 parts of ethyl paraben, and 150 parts of distilled water.

[0011] Mix 1.0 kg of Salvia miltiorrhiza, 1.5 kg of Scutellaria baicalensis, 1.5 kg of Hedyotis diffusa, 2.5 kg of wild chrysanthemum, 1.5 kg of safflower, 2.0 kg of Bai Wei, and 1.5 kg of licorice. The mixed weight is 11.5 kg, add 115 liters and the concentration is 40 % ethanol aqueous solution for reflux extraction, continuous extraction 3 times, each time for 1h, and then combine the extracts; the volume of the combined extracts is 280 liters, add 1.4 kg of activated carbon, stir for 5min, stand still for 0.5h, and suction filter until the extract is clear , the extract was concentrated to 90 l...

Embodiment 2

[0012] Example 2: 15 parts of Salvia miltiorrhiza, 20 parts of Scutellaria baicalensis, 20 parts of Hedyotis diffusa, 20 parts of wild chrysanthemum, 10 parts of safflower, 15 parts of Baiwei, 10 parts of licorice, 12 parts of carbomer 980NF, 15 parts of triethanolamine, glycerin 25 parts, 50 parts of propylene glycol, 1 part of ethyl paraben, and 100 parts of distilled water.

[0013] Mix 1.5 kg of Salvia miltiorrhiza, 2.0 kg of Scutellaria baicalensis, 2.0 kg of Hedyotis diffusa, 2.0 kg of wild chrysanthemum, 1.0 kg of safflower, 1.5 kg of Baiwei, and 1.0 kg of licorice. The mixed weight is 11 kg, add 110 liters and the concentration is 60 % ethanol aqueous solution for reflux extraction, continuous extraction for 3 times, each time for 1.5h, and then combine the extract; the volume of the combined extract is 250 liters, add 2.5 kg of activated carbon, stir for 10min, stand still for 1h, and suction filter until the extract is clear , the extract was concentrated to 80 liter...

Embodiment 3

[0014] Example 3: 20 parts of Salvia miltiorrhiza, 25 parts of Scutellaria baicalensis, 25 parts of Hedyotis diffusa, 25 parts of wild chrysanthemum, 5 parts of safflower, 10 parts of Baiwei, 5 parts of licorice, 20 parts of carbomer 974PNF, 20 parts of triethanolamine, glycerin 30 parts, 60 parts of propylene glycol, 1 part of ethyl paraben, 90 parts of distilled water.

[0015] Mix 2.0 kg of Salvia miltiorrhiza, 2.5 kg of Scutellaria baicalensis, 2.5 kg of Hedyotis diffusa, 2.5 kg of wild chrysanthemum, 0.5 kg of safflower, 1.0 kg of Bai Wei, and 0.5 kg of licorice. The mixed weight is 115 kg, add 115 liters and the concentration is 70 % ethanol aqueous solution for reflux extraction, continuous extraction 3 times, each 2h, and then combine the extracts; the volume of the combined extracts is 250 liters, add 5 kg of activated carbon, stir for 20min, stand still for 2h, and suction filter until the extracts are clarified. The extract is concentrated under reduced pressure to ...

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PUM

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Abstract

The invention relates to compound traditional Chinese medicine acne gel and a preparation method of the compound traditional Chinese medicine acne gel. The compound traditional Chinese medicine acne gel comprises 5-20 parts of salviae miltiorrhizae, 10-30 parts of radix scutellariae, 10-35 parts of hedyotis diffusa, 15-35 parts of wild chrysanthemum, 5-20 parts of flos carthami, 10-25 parts of cynanchum atratum, 5-15 parts of liquorice, 5-20 parts of carbomer, 10-40 parts of triethanolamine, 15-40 parts of glycerol, 0.5-2 parts of ethylparaben, 30-70 parts of propylene glycol and 50-300 parts of distilled water. According to the compound traditional Chinese medicine acne gel, the gel is extracted from multiple kinds of Chinese traditional medicine, and chemical substances, such as a hormone and a pigment, harmful to the skin are not contained. Results of animal stimulation tests show that the compound traditional Chinese medicine acne gel is gentle to the skin and free of stimulation to the skin and side effects. The compound traditional Chinese medicine acne gel has the advantages of being easy to spread, fresh, cool, free of an oily feel, good in adhesiveness and homogeneity, easy to carry and the like. The compound traditional Chinese medicine acne gel remarkably improves the medicine utilization ratio. The combination of medicine of the prescription of the compound traditional Chinese medicine acne gel enables inflammation diminishment and recovery of the injured skin to be conducted simultaneously and the effects that acne is fully cured and acne post-inflammatory hyperpigmentation is eliminated as soon as possible are achieved.

Description

technical field [0001] The invention relates to a medicine for treating acne and health care products for oily skin and acne skin, in particular to a compound traditional Chinese medicine acne gel and a preparation method thereof. Background technique [0002] Modern studies have shown that the pathogenesis of acne is generally considered to be due to strong secretion of sebaceous glands, hyperplasia of hair follicle epithelium, and blockage of the opening of sebaceous glands, and is related to the infection of Corynebacterium acnes, anaerobic bacteria and some Gram-positive bacilli. Now the dosage forms for external use of acne include ointment, cream, lotion, liniment, etc., which have certain deficiencies in the treatment of acne. For example, ointment and cream themselves contain oily ingredients, which are not suitable for the treatment of acne with strong sebaceous gland secretion. There is a certain impact; while lotion, liniment and other drugs have insufficient ...

Claims

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Application Information

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IPC IPC(8): A61K36/748A61K9/06A61P17/10
Inventor 夏庆梅刘志东张晗张学勇高志莉张池金孙精通景春晖杜天乐
Owner 上海一非医药科技有限公司
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