Drug for treatment of migraine

A migraine and drug technology, applied in the field of drugs for the treatment of migraine, can solve the problems of limited therapeutic effect of drugs, short duration of migraine, and abnormal dependent channels, etc., to inhibit platelet aggregation, dredge the qi and blood veins of the lesion, and relieve vasospasm Effect

Inactive Publication Date: 2014-01-22
周文华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The etiology of this disease is complex. Modern studies have put forward the theory of neurogenic inflammation, sensory sensitization of peripheral and central nerves, abnormal excitation of neurons and abnormal voltage-dependent channels, cortical spreading inhibition, and neurotransmitter theory. Relatively reliable evidence; Correspondingly, there are many types of drugs for the treatment of this disease, but the therapeutic effects of drugs produced according to these theories are very limited, and the abuse of western medicine has become one of the reasons for intractable headaches
[0003] Many drugs can relieve the pain of migraine, but they will recur after stopping the drug. The treatment of migraine is often persistent and repetitive. There is an urgent need for a drug that has a short period of treatment for migraine, high curative effect, and low recurrence rate.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0055] Tung leaf 76g Dijin 72g Wild poppy 71g Grapefruit leaf 63g

[0056] Litmus 66g, maple pear 61g, gasshangxiao 59g, golden knife vegetable 54g

[0057] Lagerstroemia root 51g Golden hair seven 49g Piper longum 46g Throat grass 41g

[0058] Ergot 38g Vitex 36g Clematis 26g Guanbaifu 20g.

[0059] A preparation method of a medicine for treating migraine, comprising the following process steps:

[0060] (1) Wash wild poppy, pomelo leaf, litmus, gasshangxiao, jindaocai, crape myrtle root, golden hair seven, longan, ergot and vitex, put them in a container, and add 8 to 10 times the amount of distilled water , after soaking for 5-6 hours, boil for 3-4 hours, extract; add 6-8 times of distilled water again, boil for 2-3 hours, extract; finally, add 4-6 times of distilled water, heat and boil for 1-2 hours, Extraction; combine the three extracts, filter to obta...

Embodiment 2

[0067] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0068] Tung leaf 71g Dijin 67g Wild poppy 66g Grapefruit leaf 60g

[0069] Litmus 61g, maple lotus pear 56g, gasshangxiao 56g, golden knife vegetable 51g

[0070] Lagerstroemia root 46g Golden hair seven 45g Piper longum 41g Throat grass 38g

[0071] Ergot 36g, Vitex 31g, Clematis 23g, Guanbai 16g.

[0072] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those in Example 1.

Embodiment 3

[0074] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0075] Tung leaf 69g Dijin 64g Wild poppy 61g Grapefruit leaf 57g

[0076] Litmus 56g Maple Lotus 52g Gasshang Xiao 51g Golden Knife Vegetable 47g

[0077] Lagerstroemia root 44g Golden hair seven 42g Piper longum 39g Throat grass 36g

[0078] Ergot 34g Vitex 30g Clematis 22g Guanbaifu 15g.

[0079] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those in Example 1.

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PUM

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Abstract

Belonging to the field of traditional Chinese medicines, the invention discloses a drug for treatment of migraine. The drug provided by the invention comprises the following effective raw material components: Clerodendrum japonicum leaves, Parthenocissus tricuspidata, wild opium poppies, pomelo leaves, litmus, roots of Dentiferous Dendropanax, Cynanchum amplexicaule, Orixa japonica, crape myrtle roots, Astilbe chinensis, Piper longum, Hydrocotyle vulgaris, ergot, fructus viticis, radix clematidis and Korean Mondshood Roots. The drug provided by the invention has the efficacy of nourishing liver and dispelling wind, activating blood circulation and inducing resuscitation. Compared with other similar drugs, the drug provided by the invention has the characteristics of precise compatibility, mild drug properties and obvious curative effect, can rapidly ease migraine symptoms, dredge qi, blood and venations of lesions, promote vasodilatation, regulate the body mechanism, excite the inner analgesic system, relieve vasospasm, inhibit platelet aggregation and blood vessel substance release, thus curing diseases. The drug for treatment of migraine has the characteristics of good curative effect, quick effect, no toxic or side effect, convenient taking, easy absorption, low cost, treatment of both symptoms and root causes, and hard recurrence after cure.

Description

Technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a medicine for treating migraine. Background technique [0002] Migraine is the most common vascular headache clinically, showing pulsating pain or distending pain consistent with the pulse, lowering the head, being heated, coughing hard, etc. can aggravate the headache, showing acute recurrent attacks; migraine is a common recurrent headache accompanied by symptoms such as nausea, vomiting, photophobia, and phonophobia. The main clinical manifestation of the patient is distending pain on one or both sides of the head, which is throbbing or persistent. Headache, and sometimes the pain is severe and pulsating. This headache often starts from the orbit or forehead, expands to the half side, and can also spread throughout the entire head. The incidence rate is as high as 8.4% to 28%. The repeated attacks of migraine have seriously affected the quality of life, study and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P25/06
Inventor 周文华
Owner 周文华
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