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A kind of traditional Chinese medicine preparation for treating thromboangiitis obliterans

A technology of traditional Chinese medicine preparation and thrombus occlusion, which is applied in the field of traditional Chinese medicine preparations for the treatment of peripheral thromboangiitis obliterans, can solve the problems of unsatisfactory long-term effects, unsatisfactory long-term effects, and easy recurrence of attacks, etc., and achieve Promote the regression of atherosclerotic plaque, increase blood flow in limbs, and have good curative effect

Inactive Publication Date: 2016-03-30
SHANDONG TUMOR HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oral drugs are mostly used to dispel aggregation, anti-inflammatory, thrombolytic, analgesic and other drugs, which have unsatisfactory long-term effects and are prone to recurrent attacks, which eventually lead to surgical treatment
At present, the treatment of traditional Chinese medicine for vasculitis, due to the limitation of prescription, process, dosage form and other factors, its curative effect is mostly in the aspect of relieving symptoms, although the existing Chinese patent medicine can alleviate the thrombosis occlusive vascular disease to a certain extent. course of inflammation, but its long-term effect is far from satisfying doctors and patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1 prepares a kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans

[0021] The formula is: 600g psoralen, 1000g cistanche, 600g sumac, 600g zedoary, 1200g gardenia, 900g ginseng, 600g capillary, 600g kelp, 900g honeysuckle, 600g saponins, 600g prunella vulgaris.

[0022] The preparation method is as follows: mix the above-mentioned medicines, add water to decoct twice, add 8 times the amount of water for the first time, decoct for 2 hours, filter with double-layer gauze, add 6 times the amount of water for the second time, decoct for 2 hours, filter, combine the two filtrates, Concentrate to a relative density of 1.05 (measured at 25°C), bottle, each bottle is 200ml, seal, store in a cool and dry place, and set aside.

Embodiment 2

[0023] Embodiment 2 prepares a kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans

[0024] The formula is: 6g psoraleae, 12g cistanche, 4g sumac, 6g zedoary, 10g gardenia, 9g ginseng, 4g capillary, 6g kelp, 6g honeysuckle, 6g saponins, 4g prunella vulgaris.

[0025] The preparation method is as follows: mix the above-mentioned medicines, add water to decoct twice, add 8 times the amount of water for the first time, decoct for 2 hours, filter with double-layer gauze, add 6 times the amount of water for the second time, decoct for 2 hours, filter, combine the two filtrates, Concentrate to a relative density of 1.05 (measured at 25°C), seal and store in a cool and dry place for later use.

Embodiment 3

[0026] Embodiment 3 prepares a kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans

[0027] The formula is: 9g psoralen, 6g cistanche, 6g sumac, 4g zedoary, 20g gardenia, 7g ginseng, 7g capillary, 4g kelp, 12g honeysuckle, 4g saponins, 6g prunella vulgaris.

[0028] The preparation method is as follows: mix the above-mentioned medicines, add water to decoct twice, add 8 times the amount of water for the first time, decoct for 2 hours, filter with double-layer gauze, add 6 times the amount of water for the second time, decoct for 2 hours, filter, combine the two filtrates, Concentrate to a relative density of 1.05 (measured at 25°C), seal and store in a cool and dry place for later use.

[0029] Clinical data Clinical observation of drug treatment of thromboangiitis obliterans of the present invention

[0030] Patient data: 163 cases of thromboangiitis obliterans, 73 cases of males, 90 cases of females; the age of onset was 25-65 years old; the...

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating thromboangiitis obliterans. The traditional Chinese medicine preparation is prepared from the following raw material medicines in parts by weight: 3-10 parts of fructus psoraleae, 9-15 parts of cistanche, 3-9 parts of hematoxylon, 3-9 parts of curcuma zedoary, 3-30 parts of jasmine, 6-12 parts of radix glehniae, 3-9 parts of oriental wormwood, 3-9 parts of sea-tangle, 3-15 parts of honeysuckle, 3-9 parts of spina gleditsiae and 3-9 parts of selfheal. A preparation method of the traditional Chinese medicine preparation comprises the following steps: weighing the raw material medicines, decocting the raw material medicines in water for twice, filtering, mixing filtrates obtained in the two decocting procedures, concentrating the filtrate to a relative density of 1.02-1.05 (measured at 25 DEG C) to obtain the traditional Chinese medicine preparation. As shown in clinic verification, the efficiency of the traditional Chinese medicine preparation for treating thromboangiitis obliterans, which is disclosed by the invention, is 56.4%, and the traditional Chinese medicine preparation is quick to take effect, good in curative effect and convenient to use.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating perithromboangiitis obliterans. Background technique [0002] Thromboangitis obliterans (TAO) is an inflammatory and occlusive lesion involving blood vessels, referred to as vasculitis for short, is a segmental, non-suppurative lesion that occurs in the walls of small and medium arteries, and Accompanied by intraluminal thrombosis and occlusion of the lumen, causing limb ischemia. Vasculitis mainly affects the middle and small arteries of the lower extremities, as well as accompanying veins. Patients often suffer from malnutrition of bones and surrounding soft tissues due to decompensation of limb ischemia, and ulceration and necrosis of distal limbs. The cause of this disease has not yet been clarified, but it is closely related to factors such as smoking, autoimmune diseases, and cold stimulation. Progressive lesions may involve blood vessels of the upper extremities,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/14
Inventor 董伟柴杰谢超
Owner SHANDONG TUMOR HOSPITAL
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