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Application of a kind of extracts such as Songsheng in the preparation of medicines for treating diabetes

A technology of diabetes drug and extract, applied in the field of medicine, can solve the problems such as no report of Songsheng diabetes drug yet.

Inactive Publication Date: 2015-08-05
舒礼良
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The above-mentioned documents and patents, etc., have not yet seen the report of Songsheng etc. or Songsheng etc. extracts for the preparation of drugs for the treatment of diabetes

Method used

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  • Application of a kind of extracts such as Songsheng in the preparation of medicines for treating diabetes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: Preparation of extracts such as Songsheng

[0038] (1) 5 kg of pine, etc., crushed, passed through a 20-mesh sieve, using supercritical carbon dioxide extraction technology, extraction temperature 45 ° C, extraction pressure 25 MPa, extraction time 1.5 h, extracted volatile oil, collected volatile oil, that is, pine and other extract A, super The medicinal residues A such as Songsheng after critical carbon dioxide extraction are used for standby;

[0039] (2) Use 80% ethanol as the solvent for the medicinal residues such as Songsheng in step (1), and extract by warm soaking at 70°C. The number of extractions is 3 times, and the extraction time is 2 hours each time. The amount of solvent used each time is equal to the weight of Songsheng. 12 times of that, filtered to obtain medicinal dregs B and extract, the extract recovered ethanol, concentrated, dried to obtain extract B such as Songsheng;

[0040] (3) Extract the dregs B obtained in step (2) by adding...

Embodiment 2

[0042] Embodiment 2: the preparation of extracts such as Songsheng

[0043] (1) 5 kg of pine, etc., crushed, passed through a 10-mesh sieve, using supercritical carbon dioxide extraction technology, extraction temperature 40 ° C, extraction pressure 30 MPa, extraction time 2 hours, extracted volatile oil, collected volatile oil, that is, pine and other extract A, supercritical The medicinal residues A such as Songsheng after carbon dioxide extraction are used for standby;

[0044] (2) Use 70% ethanol as the solvent for the medicinal residues such as Songsheng in step (1), and extract by warm soaking at 80°C. The number of extractions is 2 times, and the extraction time is 3 hours each time. 10 times of that, filtered to obtain medicinal dregs B and extract, the extract recovered ethanol, concentrated, dried to obtain extract B such as Songsheng;

[0045] (3) Extract the dregs B obtained in step (2) with water and reflux. The number of extractions is 1 time, and the extraction...

Embodiment 3

[0047] Embodiment 3: the preparation of the extracts such as Songsheng

[0048] (1) 5 kg of pine, etc., crushed, passed through a 50-mesh sieve, using supercritical carbon dioxide extraction technology, extraction temperature 50 ° C, extraction pressure 20 MPa, extraction time 1 hour, extracted volatile oil, collected volatile oil, that is, pine and other extract A, supercritical The medicinal residues A such as Songsheng after carbon dioxide extraction are used for standby;

[0049] (2) Use 95% ethanol as the solvent for the medicinal residue A of Songsheng in step (1), and extract it by warm soaking at 50°C. The number of extractions is 4 times, and the extraction time for each time is 1 hour. The amount of solvent used each time is equal to the weight of Songsheng. 15 times of that, filtered to obtain medicinal dregs B and extract, the extract recovered ethanol, concentrated and dried to obtain extract B such as Songsheng;

[0050] (3) Extract the dregs B obtained in step ...

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Abstract

The invention discloses new application of a lignum rhamnellae extract in preparation of drugs treating diabetes. The lignum rhamnellae extract is prepared by: taking lignum rhamnellae as a raw material, extracting volatile oil, and employing a macroporous adsorption resin purification technology to acquire a lignum rhamnellae extract A, a lignum rhamnellae extract B and a lignum rhamnellae extract C, and mixing the extracts in certain proportion, thus obtaining the lignum rhamnellae extract. The lignum rhamnellae extract provided by the invention is of great significance in preparing drugs treating diabetes.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to the application of extracts of Chinese medicinal materials in the preparation of medicines for treating diabetes, in particular to the application of extracts of pine nuts and the like in the preparation of medicines for treating diabetes. Background technique [0002] With the aging of the world's population, diabetes has become a common and frequently-occurring disease, and its incidence is on the rise in industrialized countries. According to statistics, there are about 150 million diabetic patients in the world, 80% of which are non-insulin-dependent diabetes (type 2), of which there are about 30 million in my country. The number of deaths caused by diabetes complications ranks third after cardiovascular and cerebrovascular diseases and cancer in developed countries, which has attracted great attention from all over the world, and researches on the pathogenesis and drug prevention and t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/72A61P3/10
Inventor 舒礼良张宛哲
Owner 舒礼良