Construction method of magnetic resonance imaging sensor for measuring lead ions

Abstract

The invention discloses a construction method of a magnetic resonance imaging sensor for measuring lead ions, belonging to the field of nanometer biotechnical detection. The method comprises the following steps: coupling magnetic nanoparticles with a pair of DNA (Deoxyribonucleic acid) probes respectively; assembling the DNA-coupled magnetic nanoparticles under the action of a DNA enzyme; detecting the concentration of Pb<2+> in a magnetic nanoparticle assembly by using a magnetic resonance signal. A method for detecting Pb<2+> in DNA enzyme-assembled magnetic nanoparticles on the basis of Pb<2+> dependence is provided. DNA-modified magnetic nanoparticles are taken as probes, the DNA-coupled magnetic nanoparticles are assembled into a polymer under the action of the DNA enzyme, and the Pb<2+> is detected according to the difference of the magnetic resonance signal under different Pb<2+> concentrations. The method is low in the detection limit, high in sensitivity and high in specificity. Meanwhile, a high-flux detection requirement can be met.

Description

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine

Login to View More

AI Technical Summary

Benefits of technology

This patented technology allows us to create small particles called paramagnetic beads that can attach themselves onto other molecules like proteins or nucleic acids through their chemical bonds without affecting them chemistry. These tiny bead-bound components then bind together tightly enough when placed next to each others' surfaces they are attached on. By measuring this binding process we get an indication about how much certain substances (Pb) have been added during manufacture.

Problems solved by technology

This patented technical solution describes how to accurately determine if there has any dangerous levels of environmental contamination caused due to use of chemical agents like pesticide and fertilizers during production processes for products that come under pressure. Current analyte monitoring techniques involve complex laborious procedures involving multiple steps and equipment. Therefore, this method needs to be less invasive and sensitive than existing solutions while also being able to identify potentially damaging elements without causing injury.

Images