Ginkgolide sublingual tablet and preparation method thereof

A technology of ginkgolides and sublingual tablets, which is applied in the direction of antidote, sugar-coated pills, pill delivery, etc., can solve the problems of no sublingual tablet preparations, achieve good taste, improve compliance, and ensure the effect of treatment
CN103976967AInactive Publication Date: 2014-08-13HUNAN UNIV OF SCI & ENG
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HUNAN UNIV OF SCI & ENG
Publication Date
2014-08-13
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a ginkgolide sublingual tablet, belonging to the technical field of a pharmaceutical composition, and a preparation method thereof. The sublingual tablet comprises the following materials in parts by weight: 1-200 parts of ginkgolide, 2-20 parts of a disintegrating agent and 40-200 parts of a filler, wherein the ginkgolide includes the following components in percentage by weight: 35-50% of ginkgolide A, 6-16% of ginkgolide B, 15-25% of ginkgolide C and 30-45% of bilobalide. The ginkgolide sublingual tablet disclosed by the invention is prepared by organically combining the disintegrating agent, the filler and the like; the sublingual tablet, which is located under the tongue when being taken, can disintegrate rapidly under the tongue; the sublingual tablet is absorbed through sublingual mucosa and directly participates in blood circulation through jugular vein and superior vena cava to become effective rapidly, so as to relieve migraine rapidly.
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Description

technical field

[0001] The invention belongs to the technical field of pharmaceutical compositions, and in particular relates to a ginkgolide sublingual tablet and a preparation method thereof. Background technique

[0002] Ginkgo biloba preparations are currently one of the most important drugs used for the treatment and prevention of cardiovascular and cerebrovascular diseases in the world and at home, and are also the herbal medicines with the largest sales volume and widest acceptance. my country's ginkgo resources account for more than 70% of the world's total resources. The annual output of ginkgo leaves is as high as 20,000 tons, and the annual output of ginkgo leaf standard extract (EGb761) is more than 100 tons. The raw materials are sufficient. The raw materials of foreign ginkgo products are also mainly from my country. The export value of Ginkgo biloba and Ginkgo biloba standard extracts ranks first in Chinese herbal medicines in my country. But the research and ...

Claims

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