Traditional Chinese medicine for treating chronic urticaria and preparation method thereof

A technology of traditional Chinese medicine and nettle root, which is applied in the field of traditional Chinese medicine for treating chronic urticaria and its preparation, which can solve problems such as drowsiness and side effects, and achieve definite curative effect and less toxic and side effects

Inactive Publication Date: 2014-08-27
苏鹏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, levocetirizine hydrochloride is mainly used in the clinical treatment of chronic urticaria. It is a new generation of highly effective non-sedating antihistamine drugs, and it is the R-isomer of cetirizine hydrochloride. It is a highly selective peripheral H1 receptor antagonist. It has a good curative effect on chronic urticaria, but it has certain side effects of drowsiness

Method used

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Experimental program
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Effect test

preparation example Construction

[0041] The present invention also provides the preparation method of above-mentioned Chinese medicine, and the dosage form of described Chinese medicine is tablet, and its preparation method comprises the following steps:

[0042] Step 1: Mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 85-95% that is 5-7 times the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first extraction liquid, the dregs obtained by filtering are then added with ethanol with an alcohol concentration of 85-95% relative to the mass of dregs, which is 3-5 times the mass of the dregs, heated and refluxed for 1-2 hours, extracted, filtered to obtain the second extract, and the first extract Combine with the second extract, concentrate under reduced pressure to remove the ethanol solvent, and dry to obtain a dry paste;

[0043] The second step: put the dry paste obtained in the first step i...

Embodiment 1

[0050] Example 1 tablet

[0051] Take 160g of elderberry, 70g of basil, 190g of manjianghong, 170g of Tianmingjing, 110g of birch bark, 80g of nettle root, 330g of comfrey, 120g of winter lily, 60g of stinky grass, 140g of corngrass, 130g of azuki greens, 310g of blackhead grass, Lingxiaohua 80g, clipper grass 90g and cockscomb seedling 140g;

[0052] Prepare as follows:

[0053] The first step: mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 95% that is 5 times the mass of the mixture, heat and reflux for 3 hours, extract, filter to obtain the first extract, and filter the obtained drug Then add ethanol with an alcohol concentration of 95% that is 3 times the mass of the dregs, heat and reflux for 2 hours, extract, filter to obtain the second extract, combine the first extract and the second extract, and concentrate under reduced pressure to remove ethanol solvent, dried to obtain a dry paste;...

Embodiment 2

[0056] Example 2 Powder

[0057] Take 180g of elderberry, 60g of basil, 170g of manjianghong, 190g of Tianmingjing, 140g of birch bark, 70g of nettle root, 310g of comfrey, 140g of winter lily, 80g of stinky grass, 120g of corngrass, 110g of azuki greens, 340g of blackhead grass, 60g of Ling Xiaohua, 70g of clipper grass and 110g of cockscomb seedlings;

[0058] Prepare as follows:

[0059] The first step: mix the various raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 80% that is 5 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 80% relative to the quality of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first extract and the second extract, and concentrate under reduced pressure to remove Ethanol solvent, drying, obtains d...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating chronic urticaria and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises sambucus williamsii hance, basil, azoila imbricate, carpesium abrotanoides, japanese white birch bark, nettle roots, shikonin, debregeasia edulis, cymbopogon distans, carpetweeds, hylotelephium spectabile, elsholtzia winitiana, campsis grandiflora, clinopodium herbs and common cockscomb leaves. The traditional Chinese medicine is mainly used for clearing away heat, promoting eruption, promoting diuresis, activating blood circulation, dispelling wind and arresting itching, has the definite curative effect on the chronic urticaria, the recurrence rate of the chronic urticaria is low, and adverse effects are small.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating chronic urticaria and a preparation method thereof. Background technique [0002] Chronic urticaria is one of the most common allergic skin diseases in clinic. The etiology and pathogenesis of chronic urticaria are complicated, and most patients cannot find the cause of the disease. Studies have proved that the pathogenesis of urticaria not only involves humoral immunity mediated by IgE, but also cellular immunity. Under the action of various factors, it is a kind of localized edema reaction caused by dilation and increase of permeability of skin, mucous membrane and small blood vessels. [0003] At present, levocetirizine hydrochloride is mainly used in the clinical treatment of chronic urticaria. It is a new generation of highly effective non-sedating antihistamine drugs, and it i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61P17/00A61P37/08
Inventor 苏鹏
Owner 苏鹏
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