On-line integrity detecting device and method used after fully-automatic sterilization
An integrity testing, fully automatic technology used in measuring devices, testing of machine/structural components, instruments, etc.
Active Publication Date: 2014-09-17
上海东富龙拓溥科技有限公司 +1
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Problems solved by technology
[0003] The technical problem to be solved by the present invention is to provide a fully automatic online integrity detection device and method after sterilization, so as to realize the automatic online integrity detection function of the liquid dispensing system after sterilization, and avoid the damage of the filter element caused by sterilization and cannot be found problems without compromising the sterile environment of the system
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[0029] Such as figure 1 Shown is a schematic diagram of the structure of the online integrity detection device after automatic sterilization. The fully automatic post-sterilization online integrity detection device includes a water for injection pipeline, a compressed air pipeline and a pure steam pipeline. The compressed air pipeline is provided with an electric contact pressure gauge 4, and the compressed air pipeline passes through the pipeline through the first The four pneumatic valves 8 are connected to the inlet of the air filter, the outlet of the air filter is respectively connected to the fifth pneumatic valve 9, the sixth pneumatic valve 10 and the eleventh pneumatic valve 15 through the pipeline, and the fifth pneumatic valve 9 is connected to the pure air filter through the pipeline. Steam pipeline, the sixth pneumatic valve 10 is connected to the second pneumatic valve 6 through the pipeline, the eleventh pneumatic valve 15 is connected to the outlet through the ...
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The invention provides an on-line integrity detecting device and method used after fully-automatic sterilization. The device is characterized by comprising an injection water pipe, a compressed air pipe and a pure steam pipe, the compressed air pipe is connected with an air filter through a fourth pneumatic valve via a pipeline, the air filter is connected with a fifth pneumatic valve, a sixth pneumatic valve and an eleventh pneumatic valve through pipelines respectively, the fifth pneumatic valve is connected with the pure steam pipe through a pipeline, the sixth pneumatic valve is connected with a second pneumatic valve through a pipeline, the second pneumatic valve is connected with an injection water pipe and a liquid medicine inlet pipe of the filter through pipelines respectively, and the filter is connected with a integrity tester through a pipeline. According to the on-line integrity detecting device and method used after fully-automatic sterilization, the problem that damage to a filter element caused by sterilization can not be found in time is avoided, and the sterile environment of a system can not be destroyed at the same time.
Description
technical field [0001] The invention relates to a full-automatic online integrity detection control device and method, which are used for realizing online integrity detection after sterilization of a filter element of a fully automatic liquid dosing system in the pharmaceutical industry, and belong to the technical field of liquid dosing control. Background technique [0002] The liquid dispensing system in the pharmaceutical industry has many valves and complex pipelines, and has high requirements on the aseptic environment of the system. It is necessary to ensure that the integrity of the filter element is good before liquid delivery. The traditional detection method of the liquid dispensing system is offline detection before sterilization, that is, the filter element is removed from the filter housing before sterilization, and after passing the detection, it is installed on the system and then sterilized. The disadvantage of this method of detection is that the integrity ...
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Inventor 郑效东
Owner 上海东富龙拓溥科技有限公司