Application of berberine in preparing drug for treating sterility of ovulation disturbance

Abstract

The invention discloses an application of berberine in preparing a drug for treating sterility of ovulation disturbance. Studies show that berberine can promote ovulation of a patient suffering from infertility of ovulation disturbance; and during a treatment process, the probability of twins and triplets is far lower than that of an ovulation induction drug of clomiphene, thereby greatly reducing risks of multiple pregnancy and occurrence of pregnancy complications, and reducing occurrence of adverse reactions. Besides, the drug is cheap and can be accepted by the patient easily. The drug is attractive in price and quality and is worth of popularization and application. Therefore, the application of berberine in preparing the drug for treating the sterility of ovulation disturbance is provided by the invention. The novel curative effect becomes a novel indication of berberine, broadens clinical application capacity of berberine, and will achieve enormous social benefits and economic benefits.

Description

technical field [0001] The invention relates to a new use of berberine, in particular to the use of berberine in the preparation of medicines for treating ovulatory infertility. The invention belongs to the technical field of medicine. Background technique [0002] Infertility is a common disease in gynecology with complex etiology. Ovulation disorder is one of the main causes of female infertility, accounting for 25%-35% of infertility. Western medicine believes that the reasons for anovulation are as follows: ① hypogonadism caused by hypothalamus-pituitary failure, which is characterized by blood luteinizing hormone (Luteinizing Hormone, LH), follicle-stimulating hormone (Follicle-stimulating hormone, FSH) and Low estrogen level; ②Hypothalamus-pituitary dysfunction: It is characterized by abnormal secretion ratio of gonadotropin LH / FSH, such as polycystic ovary syndrome, abnormal increase in the frequency and amplitude of LH secretion, and relatively insufficient FSH secr...

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to overcome the relatively large side effects (such as: multiple pregnancy, ovary enlargement, ovarian cyst rupture, ovarian hyperstimulation syndrome, arterial thromboembolism, hot flashes, heating and liver and kidney disease) that existing ovulation-stimulating drugs exist. functional impairment, etc.), and the price is expensive, the curative effect is general, and is not conducive to shortcomings such as long-term use, thereby providing a new drug that can be used for the treatment of ovulatory infertility, that is, berberine (trade name berberine)

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