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Traditional Chinese medicine for clearing embryonic tissues and preparation method and application thereof

A tissue and traditional Chinese medicine technology, which is applied in the field of traditional Chinese medicine for removing embryonic tissue and its preparation, can solve the problems of placental tissue residue, heavy bleeding, and continuous bleeding, and achieve the effects of reducing vaginal bleeding, shortening bleeding time, and promoting uterine contractions.

Inactive Publication Date: 2015-01-21
SHANDONG PROVINCIAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, medical abortion still has problems such as long vaginal bleeding time, large amount of bleeding, and large side effects. If not treated in time, it can lead to a series of problems such as anemia, hair loss, liver and kidney damage, endometritis, pelvic inflammatory disease, and secondary infertility. Adverse consequences, and there is still 6-10% incomplete abortion rate and potential risk of massive bleeding, especially for ectopic pregnancy and cornual pregnancy with more residual placental tissue, causing greater mental pressure and physical harm to the patient. Affects the curative effect of medical abortion to a certain extent
[0003] The main problem of modern medical abortion is the failure of medical abortion. The main reason is frequent pregnancy and weak uterine contraction, resulting in residual placental tissue, incomplete abortion, and bleeding

Method used

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  • Traditional Chinese medicine for clearing embryonic tissues and preparation method and application thereof
  • Traditional Chinese medicine for clearing embryonic tissues and preparation method and application thereof
  • Traditional Chinese medicine for clearing embryonic tissues and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A traditional Chinese medicine for removing embryonic tissue, which is made of the following raw materials by weight: 15 parts of wood beetle, 18 parts of motherwort, 9 parts of trigonum, 9 parts of curcuma, 10 parts of peach kernel, 9 parts of safflower, 3 parts of rhubarb, 3 parts of Puhuang, 10 parts of Radix Paeoniae Rubra, 15 parts of Trichosanthes, 9 parts of Corydalis Corydalis, 9 parts of Clematis, 9 parts of Talc, 10 parts of Alisma, 12 parts of Angelica, and 8 parts of Achyranthes bidentata.

[0035] Preparation Process:

[0036] (1) Ethanol extraction: extract rhubarb and corydalis plus 60% ethanol (V / V) of 6 times its mass for extraction, and recover ethanol to form a thick paste with a relative density of 1.30 (70° C.) for subsequent use;

[0037] (2) Extraction of volatile oil-containing medicines: take Sanleng, Zezhu, and Angelica, add 4 times its mass of water, distill and extract volatile oil for 5 hours, collect volatile oil, and use it as a spare vola...

Embodiment 2

[0044] A traditional Chinese medicine for removing embryonic tissue, which is made of the following raw materials in parts by weight: 13 parts of ground beetle, 16 parts of motherwort, 6 parts of trigonum, 5.5 parts of curcuma, 8 parts of peach kernel, 8 parts of safflower, 2 parts of rhubarb, 2.5 parts of Puhuang, 7.7 parts of Radix Paeoniae Rubra, 10 parts of Trichosanthes, 6.7 parts of Corydalis Corydalis, 7.5 parts of Clematis, 8 parts of Talc, 7.5 parts of Alisma, 9.5 parts of Angelica, and 6.8 parts of Achyranthes bidentata.

[0045] Preparation Process:

[0046] (1) Ethanol extraction: extract rhubarb and corydalis plus 50% ethanol (V / V) of 4 times its mass for extraction, and reclaim ethanol to form a thick paste with a relative density of 1.25 (80° C.) for subsequent use;

[0047] (2) Extraction of volatile oil-containing medicines: take Sanleng, Zezhu, and Angelica, add 3 times the amount of water, distill and extract volatile oil for 4 hours, collect volatile oil, a...

Embodiment 3

[0054] A traditional Chinese medicine for removing embryonic tissue, which is made of the following raw materials in parts by weight: 18 parts of ground beetle, 24 parts of motherwort, 11 parts of trigonum, 10.5 parts of curcuma, 11 parts of peach kernel, 13 parts of safflower, 5 parts of rhubarb, 5 parts of Puhuang, 13 parts of Radix Paeoniae Rubra, 20 parts of Trichosanthes, 11.5 parts of Corydalis Corydalis, 13.2 parts of Clematis, 11.5 parts of Talc, 13.5 parts of Alisma, 12 parts of Angelica sinensis, and 10 parts of Sichuan Achyranthes bidentata.

[0055] Preparation Process:

[0056] (1) Ethanol extraction: extract rhubarb and corydalis plus 70% ethanol (V / V) with 10 times its mass for extraction, and reclaim the ethanol to form a thick paste with a relative density of 1.35 (55° C.) for subsequent use;

[0057] (2) Extraction of volatile oil-containing medicines: take Sanleng, Zezhu, and Angelica, add 10 times the mass of water, distill and extract volatile oil for 8 ho...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine for clearing embryonic tissues and a preparation method and an application thereof. The traditional Chinese medicine is made from the following raw material medicines in parts by weight: 9-22 parts of ground beeltle, 12-27 parts of leonurus, 4-14 parts of rhizoma sparganii, 4.2-14.5 parts of curcuma zedoary, 6-13.7 parts of peach kernel, 5-16.4 parts of safflower, 1.3-5.8 parts of rheum officinale, 1.2-8 parts of pollen typhae, 6-16 parts of red peony root, 8-24.5 parts of radices trichosanthis, 5-13 parts of corydalis tuber, 5.1-17 parts of radix clematidis, 5-13 parts of talc, 5-15.8 parts of rhizoma alismatis, 5-18.6 parts of angelica and 5-12 parts of radix cyathulae. The traditional Chinese medicine provided by the invention has the function of removing blood stasis, and thus is capable of clearing placenta tissues left in a uterus and promoting the uterus to contract, and the traditional Chinese medicine is singly used or cooperatively used with mifepristone to obviously accelerate the discharge of the fertilized egg, obviously reduce colporrhagia, shorten the bleeding time and obviously improve the clearing rate of embryonic residues in the uterine cavity.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine for removing embryonic tissue and its preparation method and application. Background technique [0002] According to national statistics, the number of induced abortions in my country reaches more than 10,000,000 each year, especially the number of induced abortions among barren young women is increasing day by day. Although modern medical abortion is an effective and simple non-surgical treatment for terminating pregnancy, it has the advantages of less pain, high abortion success rate and avoiding possible complications caused by entering the uterine cavity. It is accepted by the majority of unplanned pregnancy women. choose. At present, the widely used drug is mifepristone combined with misoprostol. Since 1991, the research on domestic mifepristone has been carried out in my country and it has been clinically tested for more than ten years. Howe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P15/04A61K31/567
CPCA61K36/902A61K36/9066A61K9/1652A61K31/567A61K33/12A61K35/63A61K36/21A61K36/232A61K36/286A61K36/428A61K36/533A61K36/66A61K36/708A61K36/71A61K36/716A61K36/736A61K36/88A61K36/884A61K2236/333A61K2236/331A61K2236/53A61K2236/51A61K2300/00
Inventor 王杰刘善新王平靳光乾苏酩张丽美马红霞
Owner SHANDONG PROVINCIAL HOSPITAL
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