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Preparation method of pharmaceutical preparation for treating insomnia and dreaminess

A technology of insomnia, dreaminess, and pharmaceutical preparations, applied in the field of medicine, can solve the problems of insignificant therapeutic effect, large toxic and side effects of western medicine, easy repetition of drug withdrawal, etc.

Inactive Publication Date: 2015-03-04
黄勇
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its purpose is to solve the problems of insomnia and dreaminess in the treatment of patients, overcome the serious side effects of western medicine, easy to repeat drug withdrawal, and insignificant therapeutic effect, so as to achieve the goal of treating both symptoms and root causes.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A method for preparing a drug preparation for treating insomnia and dreaminess, said preparation is prepared from the following raw materials in weight ratio,

[0037] 35 parts of angelica, 35 parts of schisandra, 30 parts of lily, 30 parts of clove, 30 parts of big belly skin,

[0038] 28 parts of amaranth, 28 parts of grass fruit, 25 parts of dandelion, 25 parts of Polygonatum odoratum, 25 parts of astragalus,

[0039] 20 parts of Rhodiola rosea, 20 parts of cinnamon, 20 parts of medlar, 20 parts of Caulis Spatholobus, 20 parts of Poria cocos,

[0040] 15 parts Cyperus Cyperi, 15 parts Cocklebur, 15 parts Radix Ophiopogonis, 15 parts Epimedium, 10 parts Cypress Kernel,

[0041] 10 parts of polygala, 10 parts of Shichangpu, 10 parts of jujube, 8 parts of acacia bark, 8 parts of licorice,

[0042] Rehmannia glutinosa 5 parts, ginseng 3 parts.

[0043] The preparation method is as follows:

[0044] (1) Weigh the raw material medicine according to the parts by weight ...

Embodiment 2

[0050] Acute Toxicity Study

[0051]Healthy rats and mice were given the pharmaceutical preparation for treating insomnia and dreaminess of the present invention by oral gavage respectively, and the gavage dose was 50 times of the intended clinical dosage. After the administration, the mice showed a slight decrease in activity and returned to normal in about 1 hour. After the administration was observed continuously for 7 days, no animal died. Their general conditions, diet, water intake, urination and weight growth were normal, and no obvious acute symptoms appeared. Toxic reactions did not cause animal death. Mice did not show obvious acute toxicity, but rats showed loose stools and decreased activity, and the target organs of acute toxicity were liver and spleen. It is suggested that the drug has low acute toxicity and is safe for clinical use.

[0052] Drug efficacy experiment: effect on sleep time of pentobarbital sodium

[0053] Animals: Kunming mice, half male and ha...

Embodiment 3

[0078] typical embodiment

[0079] Liu, female, 17 years old, a high school student, due to the pressure of the college entrance examination, nervousness caused insomnia, poor spirits, headache and dizziness. Feeling difficult to study, not concentrating in class, memory loss, upset and headache when reading books, emotional irritability, poor sleep at night with frequent dreams, listlessness during the day, unclear mind, general fatigue and weakness, I have gone to the hospital for many examinations and found nothing Found organic lesions, took drugs such as diazepam for more than half a year, no obvious improvement, insomnia is also more serious, give the drug prepared in Example 1 a course of treatment combined with psychotherapy, feel good after two courses of treatment, continue to consolidate the treatment for one After the course of treatment, I can now sleep until dawn. I wake up in the morning in good spirits, and my memory has improved significantly.

[0080] Wang, ...

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Abstract

The invention relates to a preparation method of a pharmaceutical preparation for treating insomnia and dreaminess. The preparation is prepared from the following raw materials: angelica sinensis, schisandra chinensis, lily, clove, pericarpium arecae, acalypha australis, fructus tsaoko, dandelion, radix polygonati officinalis, astragalus, rhodiola rosea, cinnamon, wolfberry, caulis spatholobi, tuckahoe, rhizoma cyperi, cocklebur fruits, radix ophiopogonis, epimedium herbs, semen boitae, polygala tenuifolia, rhizoma acori graminei, Chinese dates, cortex albiziae, liquorice, radix rehmanniae preparata and ginseng. The pharmaceutical preparation disclosed by the invention is capable of simultaneously treating both symptoms and root causes of insomnia and dreaminess, free of side effects, low in price, simple and convenient to prepare and wide in application prospect.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a method for preparing a medicinal preparation for treating insomnia and dreaminess. [0002] Background technique [0003] Insomnia usually refers to a subjective experience of patients who are not satisfied with sleep time and / or quality and affects daytime social function, including difficulty in falling asleep, frequent awakening and / or early morning awakening. It can cause symptoms such as fatigue, restlessness, general malaise, listlessness, slow response, headache, and inability to concentrate. The common clinical types are: primary sleep disorder, secondary sleep disorder, pseudo-insomnia. With the rapid development of social economy and the acceleration of the pace of life, the social environment has undergone tremendous changes, which has brought tension, pressure and competition to people's life and work, directly affecting people's physical and mental ...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61K9/48A61P25/20A61P1/08A61P9/06A61P43/00A61P15/10
CPCA61K9/0053A61K9/48A61K36/076A61K36/14A61K36/232A61K36/258A61K36/28A61K36/288A61K36/296A61K36/41A61K36/47A61K36/48A61K36/481A61K36/484A61K36/486A61K36/54A61K36/57A61K36/61A61K36/69A61K36/725A61K36/79A61K36/804A61K36/815A61K36/888A61K36/889A61K36/8905A61K36/8967A61K36/8968A61K36/8969A61K36/9064A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 黄勇
Owner 黄勇
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