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A Natural Supplement for Physical Fatigue

A technology for relieving physical fatigue and antagonists, applied in the field of biological activity of natural substances, achieving the effects of low production costs, clear active ingredients, and abundant resources

Inactive Publication Date: 2016-08-17
GUANGZHOU COTIME HEALTHCARE PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no literature report that these cinnamic amide compounds have anti-fatigue biological activity

Method used

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  • A Natural Supplement for Physical Fatigue

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1: the preparation of N-methyl-cinnamon amide capsule

[0019] prescription:

[0020] N-Methyl-Cinnamamide 10g

[0021] Lactose 50g

[0022] Microcrystalline Cellulose 80g

[0023] tert-butyl-4-hydroxyanisole (BHA) 0.1g

[0024] Micronized silica gel 5g

[0025] 95% ethanol solution of 6% PVP appropriate amount

[0026] Preparation process: pass the N-methyl-cinnamon amide, lactose, microcrystalline cellulose, tert-butyl-4-hydroxyanisole and micropowder silica gel in the prescription through a 100-mesh sieve, mix well, add 95% of 6% PVP Appropriate amount of % ethanol solution is granulated, dried at 60°C, granulated with 18 mesh sieve, and the capsules can be filled.

Embodiment 2

[0027] Embodiment 2: Experimental study on the influence of N-methyl-cinnamon amide on the exercise capacity of exercise-trained rats

[0028] 36 SPF grade male SD rats, body weight 220-260g. Rats were adaptively fed for one week, in a breeding room with natural light, good ventilation, and a temperature of 22-24°C. They were fed with standard mixed feed and had free access to water and food. After the test started, all the rats were randomly divided into blank control group, high-dose supplementation group and low-dose supplementation group, and then carried out effective training with heavy load. The swimming tank is 150cm×60cm×70cm, the water depth is 60cm, and the water temperature is 32-34°C. Blank control group: Adaptive swimming for 60 minutes in the first week, gradually increased the exercise time to 150 minutes in the second week, and trained for 6 days a week for a total of 8 weeks, and administered a placebo (10 mL of normal saline) after each training. Supplemen...

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Abstract

The invention relates to a natural enriching substance for relieving physical fatigue. The natural enriching substance takes N-methyl-cinnamic amide as an active ingredient and can effectively resist peroxidatic reaction in muscle cells so as to delay the generation of sport fatigue. Besides, the natural enriching substance provided by the invention is easy to detect, a quality standard can be set and the natural enriching substance can meet market access rules of European and American countries.

Description

technical field [0001] The invention belongs to the technical field of bioactive application of natural substances, and in particular relates to a natural supplement for alleviating physical fatigue. Background technique [0002] The increasing pace of life in modern society, increasing work pressure, and increasingly fierce competition make people often feel tired. According to the WHO survey, more than 35% of people in the world are in a state of fatigue, and the fatigue state of middle-aged male population reaches 60%. The emergence of fatigue can lead to reduced exercise capacity, reduced work efficiency, and increased accidents. If fatigue is not recovered in time after the occurrence, it will gradually accumulate and lead to "overwork" and "chronic fatigue syndrome (CFS)". )", "Overtraining Syndrome", etc., causing endocrine disorders, decreased immunity, and even organic diseases, threatening human health. Due to the ambiguity and complexity of the fatigue mechanism...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/10A61K31/165A61P39/06
CPCA23V2002/00A61K36/00A23V2200/30
Inventor 陈友文
Owner GUANGZHOU COTIME HEALTHCARE PROD
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