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Medicine for regulating intestinal flora imbalance of spleen deficiency syndrome and preparation method thereof

A technology of intestinal flora imbalance and medicine, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as unsatisfactory effects, and achieve the effect of improving diarrhea and good taste

Active Publication Date: 2017-11-10
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is still a lack of effective traditional Chinese medicine preparations for regulating intestinal flora imbalance. Although some studies have shown that some spleen-invigorating traditional Chinese medicines can regulate intestinal flora imbalance, such as Shenlingbaizhusan and Sijunzi Decoction, clinical practice has proved that their effects are still unsatisfactory. , it is still necessary to develop more effective spleen-invigorating traditional Chinese medicine preparations that can regulate intestinal flora imbalance

Method used

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  • Medicine for regulating intestinal flora imbalance of spleen deficiency syndrome and preparation method thereof
  • Medicine for regulating intestinal flora imbalance of spleen deficiency syndrome and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Embodiment 1 (granule):

[0060] Take 2500g of Gorgon fruit, 2500g of white lentils, 1500g of yam, 1500g of Yizhiren, 1000g of tangerine peel, and 1000g of papaya, and implement according to the following steps:

[0061] (1) Weigh the raw material medicine according to the proportion, add water and decoct 3 times, add 8 times of water for the first time and boil, then boil for 30 minutes, add 7 times of water for the second time and boil for 40 minutes, add water 6 times for the third time After double boiling, boil for 60 minutes;

[0062] (2) Combine the decoctions, filter and concentrate the filtrate at 65°C to a clear paste with a density of 1.30, put it in an oven at 70°C to dry it into a dry paste, and grind it into fine powder;

[0063] (3) Mix the obtained dry cream powder with powdered sugar and dextrin in a weight ratio of 1:1:0.5, then add water to make granules, dry, granulate, pack into bags, and divide into 10g / bags.

Embodiment 2

[0064] Embodiment 2 (granule):

[0065] Take 3000g of Gorgon fruit, 3000g of white lentils, 1500g of yam, 1500g of Yizhiren, 500g of tangerine peel, and 500g of papaya, and implement according to the following steps:

[0066] (1) Weigh the raw material medicine according to the proportion, add water and decoct 3 times, boil for 40 minutes after boiling for 9 times for the first time, boil for 50 minutes for 50 minutes after boiling for 8 times for the second time, and boil for 50 minutes for the third time after boiling for 7 times Boil for 60 minutes;

[0067] (2) Combine the decoctions, filter and concentrate the filtrate at 75°C to a clear paste with a density of 1.25, put it in an oven at 75°C

[0068] (3) Mix the obtained dry cream powder with powdered sugar and dextrin in a weight ratio of 1:1:0.5, then add water to make granules, dry, granulate, pack into bags, and divide into 10g / bags.

Embodiment 3

[0069] Embodiment 3 (granule):

[0070] Take 2000g Gorgon, 2000g white lentils, 1800g yam, 1800g Yizhiren, 1200g tangerine peel, 1200g papaya, follow the steps below:

[0071] (1) Weigh the raw material medicine according to the proportion, add water and decoct 3 times, boil for 30 minutes after 10 times boiling for the first time, decoct for 50 minutes after boiling for 9 times for the second time, and decoct for 50 minutes after boiling for 8 times for the third time Boil for 60 minutes;

[0072] (2) Combine the decoctions, filter and concentrate the filtrate at 85°C to a clear paste with a density of 1.20, put it in an oven at 80°C to dry it into a dry paste, and grind it into fine powder;

[0073] (3) Mix the obtained dry cream powder with powdered sugar and dextrin in a weight ratio of 1:1:0.5, then add water to make granules, dry, granulate, pack into bags, and divide into 10g / bags.

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Abstract

The invention relates to a medicine for regulating intestinal flora imbalance of spleen deficiency syndrome. The medicine is composed of active ingredients and medically acceptable excipients, wherein the active ingredients are prepared from the following raw materials by weight: Gorgon 20 ~30%, white lentils 20~30%, yam 15~18%, Yizhiren 15~18%, tangerine peel 5~12%, papaya 5~12%. The medicament of the present invention can be in the form of granules, capsules, tablets or pills. After clinical verification, the medicine of the present invention can effectively regulate the imbalance of intestinal flora in patients with spleen deficiency syndrome, and can significantly improve the main symptoms such as diarrhea and abdominal distension caused by intestinal flora imbalance. Most of the drugs are of homologous nature of medicine and food, and have the advantages of good taste and suitable for long-term use.

Description

technical field [0001] The invention relates to a medical preparation, in particular to a pharmaceutical preparation containing an undetermined structure from traditional Chinese medicine, which has the function of regulating intestinal flora imbalance of spleen deficiency syndrome. Background technique [0002] The human intestinal tract is inhabited by a wide variety and a large number of bacterial microorganisms. The weight of the bacteria in the adult intestinal tract is more than 1 kg, which is close to 1 / 60-1 / 50 of the body weight. There are nearly 1,000 types of bacteria in the intestinal tract, and their number can reach 10 13 -10 14 It is 10 times the total number of human cells, and the total number of genomes encoded by it is 100 times that of human beings. The sum total of genomic information is called the "gut metagenome" (gut metagenome), which is considered to be the "human second genome" that controls human health. The intestinal metagenome cooperates wit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9062A61P1/00A61P1/12A61P1/14
Inventor 刘子志陈冠林
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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