Scutellaria barbata extract as well as preparation method and application thereof

A technology of Scutellaria barbata extract and medicine, which is applied in the direction of medical formula, plant raw materials, medical preparations containing active ingredients, etc., and can solve the anti-EBV virus cleavage of the chloroquine-type diterpene component of Scutellaria barbata. Replication activity and other issues, to achieve a good inhibitory effect, the effect of great application prospects
CN104644744AInactive Publication Date: 2015-05-27广州市爱菩新医药科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
广州市爱菩新医药科技有限公司
Publication Date
2015-05-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention belongs to the technical field of Chinese herbal medicine extraction and in particular discloses a scutellaria barbata extract as well as a preparation method and application thereof. Three compounds in a new structure and four compounds in a known structure are separated from the scutellaria barbata extract. The seven compounds have good inhibiting effects on EB (Epstein-Barr) virus replication and have low toxic and side effects; therefore the seven compounds have great application prospects in preparing medicines for preventing EB virus infection.
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Description

technical field

[0001] The invention relates to the technical field of extraction of traditional Chinese medicinal materials, and more specifically relates to an extract of Scutellaria barbata and its preparation method and application. Background technique

[0002] Human herpesviruses can be divided into α, β and γ subtypes according to their biological characteristics, among which Epstein-Barr virus (Epstein-Barr virus) belongs to γ ​​subtype, also known as type 4 human herpesvirus (HHV-4). Epstein-Barr virus was first discovered by Epstein and Barr in 1964 from a lymphoma cell line cultured in vitro from African children's malignant lymphoma (Burkitt lymphoma), and a new herpes virus was discovered by electron microscopy, and it was named Epstein-Barr virus. The genome of EBV is a linear double-stranded DNA with a length of 172kb and encodes about 100 genes. Like human herpesviruses, EBV has two life cycles, a latent and lytic phase. In the latent phase, EBV expresses o...

Claims

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