Application of dogwood nano powder to resist type-2 diabetes

A technology of type 2 diabetes mellitus and cornus, applied in the field of biomedicine, can solve the problems of western medicine side effects, high cost, drug resistance price, etc., and achieve the effects of lowering blood sugar, no toxic side effects, and considerable development and application value.

Inactive Publication Date: 2015-06-10
SHAANXI NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the research and development of diabetes drugs has become an urgent task, and western medicine is still the main drug for the treatment of diabetes at present, such as sulfonylureas, thiazolidinones, metformin and α-glucosidase inhibitors, etc. Diabetes has a significant effect, but western medicine can cause various side effects, drug resistance and is expensive, especially most western medicines only target a single pathway to control hyperglycemia, while diabetes is a disease with multiple etiologies. Simple hypoglycemic Therapy can only relieve symptoms, but cannot solve other symptoms such as lipid metabolism disorders, inflammation, etc.

Method used

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  • Application of dogwood nano powder to resist type-2 diabetes
  • Application of dogwood nano powder to resist type-2 diabetes
  • Application of dogwood nano powder to resist type-2 diabetes

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Experimental program
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Effect test

Embodiment Construction

[0024] The present invention will be further described in detail below in conjunction with specific embodiments, which are explanations of the present invention rather than limitations.

[0025] 1. Experimental materials

[0026] 1. Dogwood:

[0027] The cornus used in the experiment was harvested from Foping County, Shaanxi Province in October 2012, and was identified as the mature fruit of Cornus officinalis Sieb.Et Zucc. by Professor Wang Zhezhi, School of Life Sciences, Shaanxi Normal University.

[0028] 2. Experimental animals: SPF grade, male Kunming mice, weighing 15±2g, provided by the Animal Center of Xi'an Jiaotong University School of Medicine.

[0029] 3. Experimental reagents: streptozotocin (sigma company); glimepiride (Guizhou Tianan Pharmaceutical Co., Ltd.); triglyceride (TG) kit (Beijing Beihua Kangtai Clinical Reagent Co., Ltd.); high density Lipoprotein cholesterol (HDL) kit (Beijing Beihua Kangtai Clinical Reagent Co., Ltd.); total cholesterol (TC) kit ...

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Abstract

The invention discloses application of dogwood nano powder to resist type-2 diabetes, and belongs to the technical field of biological medicine. According to the application, nano pulverization is conducted on dogwood medicinal materials, the processed dogwood medicinal materials can be used for preparing medicine for treating the diabetes, the problems that western medicine is singular in blood glucose lowering way, large in side effects and the like, and a basis for lowering the blood glucose through active ingredients of the traditional Chinese medicine is provided. A dogwood iridoid glycoside is safer, more effective, moderate, lasting in effect and free of toxic and side effect, the action mechanism is multiple in effect, multiple in target spot and multiple in function, the effect is not only limited to lowering the blood glucose, meanwhile the dogwood nano powder is significant in preventing and curing the diabetic complication, and therefore, the dogwood nano powder has considerable developing and application value on the aspect of improving the diabetes.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to the application of dogwood nanopowder for resisting type 2 diabetes. Background technique [0002] Diabetes mellitus is a widespread epidemic disease caused by insulin deficiency, decreased insulin secretion, or impaired pancreatic β-cell function. Studies have shown that there are approximately 1.5 billion diabetics worldwide and the incidence of diabetes is expected to double by 2025. Therefore, the research and development of diabetes drugs has become an urgent task, and Western medicine is still the main drug for the treatment of diabetes at present, such as sulfonylureas, thiazolidinones, metformin and α-glucosidase inhibitors, etc. Diabetes has a significant effect, but Western medicine can cause various side effects, drug resistance and is expensive, especially most Western medicines only target a single pathway to control hyperglycemia, and diabetes is a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/40A61K9/14A23L1/29A61P3/10A61P3/06A23L33/00
Inventor 康杰芳白嫄王韶君王红菊杨宁王喆之
Owner SHAANXI NORMAL UNIV
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