Application of umbilical cord blood immune cells in the preparation of drugs for treating psoriasis
A technology of immune cells and umbilical cord blood, applied in the field of biomedicine, can solve the problems of poor sensitivity and easy recurrence of conventional treatment methods, and achieve the effect of remission and control of the disease, good compliance and good tolerance
Active Publication Date: 2017-03-15
HARBIN MEDICAL UNIVERSITY
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Problems solved by technology
[0006] Aiming at the current clinical characteristics of psoriasis with long course of disease, poor sensitivity to conventional treatment methods, easy recurrence, and suffering after suffering, and according to the pathological characteristics of immune imbalance in psoriasis patients, the present invention utilizes neonatal umbilical cord blood Immune cells, after targeted expansion in vitro, are infused into patients to correct immune biases or deficiencies in patients
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[0034] The present invention will be further described through experiments and examples below. It should be understood that these examples are only for the purpose of illustration, and in no way limit the protection scope of the present invention.
[0035] Example 1 Separation and cultivation of umbilical cord blood immune cells in vitro
[0036] 1. Cord blood collection
[0037] 1) Spare parts: 1 umbilical cord blood collection bag, 1 "Donor Health and Information Collection Registration Form", 3 sterile hemostatic forceps, 1 sterile scissors, 1 pair of sterile gloves, 500ml sterile normal saline, Several pieces of sterile gauze, iodine, 75% ethanol;
[0038] 2) Before cord blood collection, check whether there is any defect in the equipment used for blood collection, to ensure that the cord blood collection bag has no leakage, the anticoagulant has not deteriorated, and there is no turbidity and foreign matter, and within the shelf life, check whether the information collec...
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The invention discloses an application of umbilical cord blood immune cells in preparation of a medicine used for treating psoriasis and belongs to the technical field of biological medicines. According to the application of the umbilical cord blood immune cells in preparation of the medicine used for treating psoriasis, immune cells in neonatal cord blood are utilized, after in vitro directional amplification is finished, and then the immune cells are infused into a patient for correcting in vivo immunity bias or defect; and by virtue of experimental treatment, results prove that treatment effect of the umbilical cord blood immune cells on the patient suffering from psoriasis is obvious. The application of the umbilical cord blood immune cells in preparation of the medicine used for treating psoriasis has the advantages that a therapeutic method is simple, treatment is easy, compliance of the patient is good, no obvious side effect is produced, more importantly, the therapeutic method can reach clinical healing level, and the patient can obtain long-term clinical disease-free remission.
Description
technical field [0001] The invention relates to the application of immune cells in the preparation of medicines for treating psoriasis, in particular to the application of umbilical cord blood immune cells in the preparation of medicines for treating psoriasis, and belongs to the technical field of biomedicine. Background technique [0002] Psoriasis, commonly known as "psoriasis", is a common chronic inflammatory skin disease that is prone to recurrence. The characteristic damage is red papules or plaques covered with multiple layers of silvery white scales. The incidence is the most in young adults, more in men than in women, more in the north than in the south, prone to or aggravated in spring and winter, and relieved in summer and autumn. The etiology and pathogenesis are not completely clear. Studies have found that the incidence of this disease is related to genetic factors, streptococcus infection, abnormal immune function, metabolic disorders and endocrine changes. ...
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IPC IPC(8): C12N5/078A61K35/51A61P17/06
Inventor 张艳桥黄小义李志伟王新玲吕慧敏
Owner HARBIN MEDICAL UNIVERSITY