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Traditional Chinese medicine for treating damp heat stagnation type pancreatic cancer and preparation method thereof

A technology of pancreatic cancer and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine for the treatment of damp-heat stagnant pancreatic cancer and its preparation, can solve the problems of poor treatment effect, misdiagnosis and mistreatment of advanced pancreatic cancer, and achieve the purpose of enhancing the body's immunity and prolonging the survival period , the effect of inhibiting the growth of cancer cells

Inactive Publication Date: 2015-10-07
张晓艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The early symptoms of pancreatic cancer are not typical, and often manifest as symptoms similar to those of other organ lesions, leading to some symptomatic patients being misdiagnosed and mistreated. Most patients diagnosed with pancreatic cancer already have distant metastasis or signs of distant metastasis Advanced pancreatic cancer, but Western medicine is not effective in treating advanced pancreatic cancer. It can only be surgery, radiotherapy, chemotherapy, cutting and cutting until the end of life. Patients have been in pain, and less than 20% of patients have radical surgery hope

Method used

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Experimental program
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Effect test

preparation example Construction

[0044] The present invention also provides a preparation method of the above-mentioned Chinese medicine. When the dosage form of the Chinese medicine is a tablet, the preparation method includes the following steps:

[0045] In the first step, the raw materials of the traditional Chinese medicine are mixed in proportion, and ethanol with an alcohol concentration of 85-95% relative to the mass of the mixture is added, heated and refluxed for 1 to 3 hours, extracted, and filtered to obtain the first extract The dregs obtained by filtration are then added to ethanol with an alcohol concentration of 85-95% relative to the mass of the dregs by 1 to 2 times, heated to reflux for 1 to 3 hours, extracted and filtered to obtain a second extract; the first extraction The liquid and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0046] In the second step, the dry paste obtained in the first step is placed ...

Embodiment 1

[0053] Example 1: Tablet

[0054] Take 150g of yarrow, 240g of coronet, 80g of plow tip, 130g of sage, 140g of tangerine, 260g of dayflower, 180g of melaleuca, 270g of serrata, 360g of horsetail, 350g of lotus, and 160g of rock flower , Pine tree 320g, bean tree 120g, original silk moth 260g, self-eliminating capacity 110g and Huaier 390g.

[0055] The preparation method includes the following steps:

[0056] In the first step, the raw materials of the traditional Chinese medicine are mixed in proportion, and ethanol with an alcohol concentration of 85% relative to the mass of the mixture is added, heated to reflux for 2 hours, extracted and filtered to obtain the first extract; the dregs obtained by filtering Then add ethanol with an alcohol concentration of 85% that is twice the mass of the drug residue, heat and reflux for 2 hours, extract, and filter to obtain a second extract; combine the first extract and the second extract, and concentrate under reduced pressure to remove Et...

Embodiment 2

[0059] Example 2 Granules

[0060] Take 170g of yarrow, 210g of coronet, 120g of plow tip, 90g of fragrant peel, 160g of tangerine, 290g of dayflower, 200g of melaleuca, 240g of serrata, 390g of horsetail, 320g of lotus, and 180g of rock flower , Pine 290g, bean tree 150g, original silkworm moth 240g, self-eliminating capacity 140g and Huaier 360g.

[0061] The preparation method includes the following steps:

[0062] Step 1: Mix the raw materials according to the stated proportions, add 5 times the alcohol concentration of 95% ethanol to the mixture, heat to boiling and reflux for 3 hours, filter, use the reflux liquid as the solvent, the filter residue as the solute, and use percolation The method is used to slowly permeate at a speed of 2ml per minute, collect the percolate, and then concentrate it under reduced pressure under a vacuum of 0.08Mpa to a paste with a relative density of 1.05 at 55°C, spray drying, and the inlet air temperature of the spray dryer 170°C, air outlet t...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating damp heat stagnation type pancreatic cancer and a preparation method thereof. All raw medicinal materials of the traditional Chinese medicine comprise achillea millefolium, herb of sword brake, typhonium divaricatum, Chinese silkvine root-bark, all-grass of matsumura leafflower, setcreasea purpurea, lycopodium serratum, elsholtzia patrini garcke, meadowrue root and rhizome, herb of Japanese farfugium, tushihua, baeckea frutescens, radermachera sinica, silkworm moth, stem and leaf of assam crotalaria and trametes robinioplila. The traditional Chinese medicine provided by the invention can be separately used or can be matched with chemoradiotherapy for use; the traditional Chinese medicine can be used for reducing lumps in a short time, effectively controlling the diffusion and transfer of cancer cells, and enhancing the body immune function to suppress the growth of the cancer cells; meanwhile, no side effects are caused; the aims of enhancing the body immunity while treating and resisting the cancer, relieving pains of patients, stabilizing disease conditions, prolonging the survival period and increasing the proportion of patients realizing clinical complete remission are achieved.

Description

Technical field [0001] The present invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine for treating pancreatic cancer of damp-heat stagnation type and a preparation method thereof. Background technique [0002] Pancreatic cancer is rare in malignant tumors of the digestive tract. It is more common in the age of 40 to 60. There are more men than women. Pancreatic cancer mostly occurs in the head of the pancreas, and only a few occur in the body and tail of the pancreas. The clinical symptoms of pancreatic cancer are different due to the difference in the location and the course of the disease. Abdominal pain is the earliest symptom, which is more common in the body and tail of the pancreas, and mostly radiates to the lower back. The disease may have jaundice in the development process, and abdominal masses and fever may appear in the late stage. The supraclavicular lymph node is the most common metastatic site....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P35/00A61K35/64
Inventor 张晓艳孙德重
Owner 张晓艳
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