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A kind of muscle tissue repair material and preparation method thereof

A technology for repairing materials and muscle tissue, applied in medical science, prostheses, etc., can solve the problems of artificial muscles that consume a lot of energy and cannot repair themselves, and achieve the effect of no toxic side effects and strong repair ability

Active Publication Date: 2017-09-12
丰德医学科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Technical problem to be solved: the present invention provides a muscle tissue repair material and its preparation method to solve the problems in the prior art that artificial muscles need to consume a lot of energy, or cannot be self-repaired due to failure

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A muscle tissue repair material, mainly made of the following raw materials according to the ratio of parts by mass: 25 parts of actin, 16 parts of myosin, 12 parts of aminodextran, 8 parts of hyaluronic acid, and 6 parts of chitosan , 2 parts of fibronectin, 8 parts of keratin, 5 parts of valine, 3 parts of proline, 4 parts of glycine, 35 parts of double distilled water.

[0025] A method for preparing a muscle tissue repair material, comprising the following steps:

[0026] (1) Dissolve actin, fibronectin, valine and proline in double distilled water, heat to 25°C to make slurry 1; deposit slurry 1 in a mold, cool until slurry 1 transforms is the temperature of multiple crystals or particles;

[0027] (2) heating the crystals or particles obtained in step (1) to 62°C to obtain the porous composite material 1, and taking the material out of the mold;

[0028] (3) Dissolve myosin, keratin, hyaluronic acid and glycine in double distilled water, heat to 25°C to make slu...

Embodiment 2

[0031] A muscle tissue repair material, which is mainly made of the following raw materials in proportion by mass: 34 parts of actin, 32 parts of myosin, 23 parts of aminodextran, 19 parts of hyaluronic acid, and 21 parts of chitosan , 12 parts of fibronectin, 21 parts of keratin, 13 parts of valine, 8 parts of proline, 7 parts of glycine, 54 parts of double distilled water.

[0032] A method for preparing a muscle tissue repair material, comprising the following steps:

[0033] (1) Dissolve actin, fibronectin, valine and proline in double distilled water, heat to 34°C to make slurry 1; deposit slurry 1 in a mold, and cool until slurry 1 transforms is the temperature of multiple crystals or particles;

[0034] (2) heating the crystals or particles obtained in step (1) to 79°C to obtain the porous composite material 1, and taking the material out of the mold;

[0035] (3) Dissolve myosin, keratin, hyaluronic acid and glycine in double distilled water, and heat to 34°C to make...

Embodiment 3

[0038] A muscle tissue repair material, which is mainly made of the following raw materials in proportion by mass: 40 parts of actin, 38 parts of myosin, 30 parts of aminodextran, 25 parts of hyaluronic acid, and 26 parts of chitosan , 15 parts of fibronectin, 27 parts of keratin, 17 parts of valine, 12 parts of proline, 11 parts of glycine, 65 parts of double distilled water.

[0039] A method for preparing a muscle tissue repair material, comprising the following steps:

[0040] (1) Dissolve actin, fibronectin, valine and proline in double distilled water, heat to 38°C to make slurry 1; deposit slurry 1 in a mold, cool until slurry 1 transforms is the temperature of multiple crystals or particles;

[0041] (2) heating the crystals or particles obtained in step (1) to 89°C to obtain the porous composite material 1, and taking the material out of the mold;

[0042] (3) Dissolve myosin, keratin, hyaluronic acid and glycine in double distilled water, heat to 38°C to make slurr...

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PUM

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Abstract

The invention discloses a muscle tissue repair material and a preparation method thereof. It is mainly prepared from the following raw materials according to the ratio of parts by mass: 25-40 parts of actin, 16-38 parts of myosin, and 12-38 parts of aminodextran. 30 parts, 8~25 parts of hyaluronic acid, 6~26 parts of chitosan, 2~15 parts of fibronectin, 8~27 parts of keratin, 5~17 parts of valine, 3~12 parts of proline, Glycine 4~11 parts, double distilled water 35~65 parts. Compared with the prior art, the present invention has the following beneficial effects: firstly, the muscle tissue repair material prepared by the present invention does not need to consume too much energy; secondly, the muscle tissue repair material prepared by the present invention has a strong repair ability for muscle tissue; finally, The muscle tissue repair material prepared by the invention has no toxic and side effects on human body.

Description

technical field [0001] The invention relates to the field of medical biomaterials, in particular to a muscle tissue repair material and a preparation method thereof. Background technique [0002] Nishi Miyagawa, a researcher from Arizona State University, believes that human muscles are the motors for the movement of human limbs. Only by producing super artificial muscles and devices can the prosthetics of disabled people restore their normal functions. This new artificial muscle will have Potential treatment of the neuromuscular disease Parkinson's disease. To this end, scientists have used bionics to create this magical "biological motor" through the study of the muscles of toads and chameleons. [0003] Scientists have discovered that the jaw muscles of a toad can generate a force 700 times greater than its own body weight, and when a chameleon preys, the force generated by the contraction of the tongue muscles is also amazing. At present, the best mechanical equipment ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/26
Inventor 何国伟孙加升刘秀梅
Owner 丰德医学科技有限公司