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Microneedle applicator including counter assembly

A technology of applicator and counter, which is applied in the direction of microneedle, needle, drug equipment, etc.

Active Publication Date: 2016-08-10
3M INNOVATIVE PROPERTIES CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, microneedle penetration within skin tissue to a precise level and with good reproducibility is often a challenging task

Method used

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  • Microneedle applicator including counter assembly
  • Microneedle applicator including counter assembly
  • Microneedle applicator including counter assembly

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0177] Counter Component Example

[0178] 1. A microneedle applicator, comprising:

[0179] a housing having a base and an opening formed in the base, wherein the base of the housing is configured to be positioned on a skin surface;

[0180] a microneedle array holder configured to hold a microneedle array;

[0181] an actuator movable relative to the housing between a first position and a second position such that the microneedle array holder moves between a retracted position and an extended position, respectively,

[0182] In the retracted position, the microneedle array is recessed within the housing such that when the base of the housing is positioned on the skin surface and the microneedle array is coupled to the microneedle array holder, the microneedle array does not contact the skin surface,

[0183] In the extended position, at least a portion of the microneedle array is positioned to contact the skin when the base of the housing is positioned on the skin surfac...

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PUM

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Abstract

The present disclosure provides a microneedle applicator. The applicator may include: a microneedle array; a microneedle array holder; and an actuator movable between a first position and a second position such that the microneedle array holder is in a retracted position, respectively to and from the extended position. The applicator may also include: a first biasing element configured to bias the actuator in the first position; and a counter assembly or mechanism configured to count the microneedles The number of times the array holder is moved between the retracted position and the extended position (or the number of times the actuator is moved from the first position to the second position). In some embodiments, the counter assembly can include an actuator and a first biasing element.

Description

technical field [0001] The present disclosure generally relates to microneedle applicators and methods for applying microneedle applicators to skin to treat an area of ​​skin and / or to deliver an active agent to the skin. Background technique [0002] Transdermal and topical drug delivery are useful for therapeutic treatment, but the number of molecules that can be effectively delivered using these routes can be limited by the barrier properties of the skin. The major barrier to transporting molecules through the skin is the stratum corneum (the outermost layer of the skin). [0003] Many different skin treatments have been proposed to increase the permeability or porosity of the outermost skin layers, such as the stratum corneum, to enhance drug delivery through or into those layers. The stratum corneum is a complex structure of compact keratinocyte remnants separated by lipid domains. The stratum corneum is formed by corneocytes, which make up most of the epidermal cells...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M37/00
CPCA61M37/0015A61M2037/0023A61M2037/003A61M2037/0046A61M2205/60
Inventor 潘恩赐孙文艺大卫·朱利叶斯潘美玲梅尔文·齐恩李志英
Owner 3M INNOVATIVE PROPERTIES CO