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A whole ganoderma lucidum anti-tumor soft capsule and its preparation method

An anti-tumor, soft capsule technology, applied in anti-tumor drugs, capsule delivery, pharmaceutical formulations, etc., to achieve the effects of easy absorption and utilization, improved quality, and considerable economic value

Active Publication Date: 2019-10-18
福建仙芝楼生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, the compound anti-tumor composition mentioned in the patent CN101559084B only uses the alcoholic water extract of Ganoderma lucidum to be compatible with other traditional Chinese medicines. Part of the aqueous extract of its spores

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0023] The present invention also provides a preparation method of the health food:

[0024] (1) Preparation of Chizhi and Zizhi extracts: Harvest mature Chizhi, wash, dry, and dry at 65°C, break into coarse particles with a particle size of less than 1 cm for extraction, add 8 to 10 Double the amount of 90%-95% ethanol, extract for 1.5-3 hours in a slightly boiling state, filter through a 200-mesh sieve, and collect the filtrate for later use; add 6-8 times the amount of 80%-90% ethanol for the second alcohol extraction, Extract for 1.5-3 hours, filter with a 200-mesh sieve, collect the filtrate, and combine it with the first filtrate; carry out water extraction after alcohol extraction, add 10-12 times the amount of water, extract for 3-5 hours in a slightly boiling state, and filter with a 200-mesh sieve , collect the filtrate for later use; add 8 to 10 times the amount of water for the second water extraction, extract in a slightly boiling state for 1.5 to 3 hours, filter ...

specific Embodiment 1

[0029] (1) Preparation of red lucidum and purple lucidum extract: harvest mature red lucidum, wash, dry, and dry at 65°C, break into 100kg of coarse particles with a particle size of less than 1cm for extraction, add 90% of 1000kg for the first alcohol extraction Ethanol, extract 3h under slight boiling state, filter with 200 mesh sieve, collect the filtrate for later use; add 800kg 80% ethanol for the second alcohol extraction, extract 3h under slightly boiling state, filter with 200 mesh sieve, collect filtrate, and the first time Combine the filtrates; carry out water extraction after alcohol extraction, add 1200kg of water, extract for 5 hours in a slightly boiling state, filter with a 200 mesh sieve, and collect the filtrate for later use; add 1000kg of water for the second water extraction, extract for 2 hours in a slightly boiling state, and use a 200 mesh Sieve and filter, collect the water-extracted filtrate twice and combine the alcohol-extracted filtrate, concentrate...

Embodiment 2

[0035] (1) Preparation of Chizhi and Zizhi extracts: Harvest mature Chizhi, wash, dry, and dry at 65°C, break into 100kg of coarse particles with a particle size of less than 1 cm for extraction, and add 800kg of 95 % ethanol, extract 2h under slightly boiling state, filter with 200 mesh sieve, collect the filtrate for subsequent use; add 600kg 90% ethanol for the second alcohol extraction, extract 2h under slightly boiling state, filter with 200 mesh sieve, collect filtrate, and the first Combine the filtrates; carry out water extraction after alcohol extraction, add 1000kg of water, extract for 4 hours in a slightly boiling state, filter with a 200 mesh sieve, and collect the filtrate for later use; add 800kg of water for the second water extraction, extract for 3 hours in a slightly boiling state, and use 200 Filter through a mesh sieve, collect twice the water-extracted filtrate and combine the alcohol-extracted filtrate, concentrate to a specific gravity of 1.05, which is ...

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Abstract

The invention discloses whole ganoderma lucidum anti-tumor soft capsules and a preparation process thereof. The health food is prepared from ganoderma lucidum spore oil, a ganoderma lucidum extractive, a ganoderma sinensis extractive, a degreased spore powder extractive, a suspending agent and capsule shells. The ganoderma lucidum anti-tumor soft capsules comprises the following contents: 70%-80% of ganoderma lucidum spore oil, 10%-15% of ganoderma lucidum extractive, 5%-10% of ganoderma sinensis extractive, 5%-10% of degreased spore powder extractive and 5% of the suspending agent. Detection results show that the content of the index component polysaccharide is not less than 5%, and the content of the ganoderic acid A is not less than 30 mg / 100g. According to the product, essence of whole ganoderma lucidum is concentrated, recycling of degreased spore powder is realized, and multiple ganoderma lucidum bioactive substances are integrated and animal experiment results show that the ganoderma lucidum anti-tumor soft capsules have the efficacy of resisting tumors and improving immunity of the organism. The prepared soft capsules are convenient to carry and are suitable for being taken by tumor patients.

Description

technical field [0001] The invention relates to the field of health food, in particular to a whole ganoderma lucidum anti-tumor soft capsule and a preparation method thereof. Background technique [0002] Tumor is a disease caused by the abnormal mechanism of controlling cell growth and proliferation. In addition to uncontrolled growth, tumor cells can also locally invade surrounding normal tissues and even transfer to other parts of the body through the circulatory system or lymphatic system in the body, seriously affecting normal physiological functions. The current methods of surgery, radiotherapy, chemotherapy and other methods all have great toxic and side effects. While killing tumor cells, they will cause systemic toxic reactions, weaken the patient's immune system, increase the difficulty of treatment, and bring great harm to the patient. Big pain. [0003] Traditional Chinese medicine is a traditional cultural treasure of the Chinese nation. In recent years, resea...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/074A61K9/48A61P35/00
Inventor 李晔金凌云黄样增姚渭溪吴长辉王琼
Owner 福建仙芝楼生物科技有限公司
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