Coronary blood flow simulation system and method based on computational fluid dynamics

A technology of coronary blood flow and computational fluid dynamics, applied in the field of computer simulation, can solve problems such as increasing medical costs, increasing the risk of death of patients, and suffering of patients, so as to reduce psychological and physical pain, reduce the risk of death, medical costs, efficiency and The effect of high reliability

Active Publication Date: 2019-02-05
BEIJING GUANSHENGYUN MEDICAL TECH CO LTD
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Problems solved by technology

[0005] In the existing medical imaging technology, the detection of vascular stenosis is still in the stage of CT and interventional arteriography imaging; and the invasive measurement stage of FFR, it is difficult to judge whether the myocardial blood supply of patients is sufficient through anatomical images alone, especially for critical In addition, radiography and FFR measurement need to place sensors, pressure guide wires, etc. to measure in the patient's body, and its invasiveness will undoubtedly cause harm to the patient's body, causing psychological and physical pain to the patient, increasing medical costs and increasing patient's risk of death

Method used

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  • Coronary blood flow simulation system and method based on computational fluid dynamics
  • Coronary blood flow simulation system and method based on computational fluid dynamics
  • Coronary blood flow simulation system and method based on computational fluid dynamics

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Embodiment 1

[0040] Clinically, examination is required to obtain information such as the size, shape, location, degree of danger, and whether it affects the blood supply of the coronary artery injury in the patient's heart. Among them, the techniques used to assess coronary artery injury of the heart can be divided into two categories: invasive examination and non-invasive examination. Invasive examination is an invasive examination, which undoubtedly brings harm to the patient's body, causes the patient's psychological and physical pain, increases medical costs and increases the risk of death of the patient. Therefore, non-invasive inspection has become a research hotspot to solve the above defects to a certain extent.

[0041] Non-invasive tests include: electrocardiogram, examination of cardiac injury markers, exercise stress test, single-photon emission computed tomography (SPECT) and positron emission tomography (PET) of myocardial perfusion ), these detection techniques indirectly ...

Embodiment 2

[0105] Such as figure 2 As shown, the present invention also provides a coronary blood flow simulation method based on computational fluid dynamics, comprising steps:

[0106] acquiring a sequence of computed tomography images of the human cardiovascular system;

[0107] extracting computed tomography data of coronary vessels according to the computed tomography image sequence of the human cardiovascular system, and performing three-dimensional reconstruction on the extracted image sequence to obtain a three-dimensional coronary artery model;

[0108] Performing preprocessing required for fluid dynamics calculations on the three-dimensional coronary artery model, including grid division, loading calculation settings, and boundary condition parameters;

[0109] Solve the three-dimensional flow control equation of blood in the coronary artery, and output the calculation results, the calculation results include one or more of pressure, blood flow reserve fraction, and blood flow ...

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Abstract

The invention provides a CFD-based coronary artery blood flow simulating system and method. The simulating system comprises a Computed tomography (CT) data obtaining system, a blood vessel 3D model reconstruction system, a CFD pre-processing system, a CFD computation system and a post-processing system, wherein the CT data obtaining system obtains a CT image sequence of cardiovascular system of the human body; the blood vessel 3D model reconstruction system carries out 3D reconstruction on the extracted image sequence to obtain a 3D coronary-artery blood vessel model; the CFD pre-processing module carries out pre-processing required by hydrodynamic computation on the 3D coronary-artery blood vessel model; the CFD computation system resolves a 3D flow control equation of blood in the coronary artery blood vessel and outputs a computation result; and the post-processing system adds the computation result to the corresponding position of the 3D coronary-artery blood vessel model, and displays color cloud atlas. The coronary artery FFR is calculated and used as the standard for assessing the coronary artery function, disadvantages in determining the blood supply state of the cardiac muscle in the coronary artery anatomy aspect are overcome patients are not sound, and the cost is lower.

Description

technical field [0001] The invention relates to the technical field of computer simulation, in particular to a coronary blood flow simulation system and method based on computational fluid dynamics. Background technique [0002] Coronary heart disease (CHD, coronary artery heart disease), referred to as coronary heart disease, is the most common heart disease. Refers to myocardial dysfunction and / or organic disease caused by coronary artery stenosis and insufficient blood supply. [0003] Coronary arteries are branches of the aorta, responsible for supplying oxygen and nutrients to the heart muscle, and have no side branches. When the coronary arteries become clogged with atherosclerotic plaque or blood clots, this results in insufficient blood flow to the heart. If atherosclerotic plaque occurs in the coronary arteries, the consequences of the evolution to the later stage are that the myocardial oxygen demand exceeds the oxygen supply. Infarction, heart attack, etc. Pat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T17/30G06T19/20
Inventor 林君山丁笑天刘豆豆端木正吴焕焕雷达
Owner BEIJING GUANSHENGYUN MEDICAL TECH CO LTD
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