Traditional Chinese medicine contrast agent for gastrointestinal B ultrasound, and preparation method for traditional Chinese medicine contrast agent

A technology of contrast agent and traditional Chinese medicine, applied in the direction of echo/ultrasound imaging agent, etc., can solve the problems of poor diagnostic accuracy of gastrointestinal diseases, failure to use gastrointestinal diseases, and delay in treatment timing, etc., to improve the accuracy of inspection and have no toxic side effects , low cost effect

Inactive Publication Date: 2015-12-02
徐永通
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the clinical diagnosis of many gastrointestinal diseases mainly relies on X-ray barium meal examination and gastroscopy examination, such as gastric ulcer and duodenal ulcer, etc., but these two examinations are both painful and painful, and have certain limitations. Universal examination, especially for children, pregnant women, the elderly and the infirm, is not easy to accept, and it is also difficult for asymptomatic people, leading to some misdiagnosis and mistreatment, and even gastrointestinal perforation or bleeding before diagnosis and treatment, delaying the timing of treatment
Although B-ultrasound has the advantages of simplicity, safety, non-invasiveness, and painlessness, it has not been adopted by more gastrointestinal diseases due to its poor diagnostic accuracy for some gastrointestinal diseases.

Method used

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  • Traditional Chinese medicine contrast agent for gastrointestinal B ultrasound, and preparation method for traditional Chinese medicine contrast agent

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preparation example Construction

[0046] When the prepared dosage form is an oral liquid, its preparation method comprises the following steps:

[0047] The first step is to mix Osmanthus chinensis, scutellaria, Nitraria japonica, dry field grass, kidney grass, black medicine leaves, seven leaf seven and parasitic yellow, and add 3 to 5 times the amount of alcohol concentration of 55% relative to the mixture Reflux extraction with ~65% ethanol for 2 to 4 times, each time for 2 hours to 3 hours, filter, combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.30 to 1.32 at 70°C, and set aside;

[0048] The second step is to mix the remaining raw medicinal materials in proportion, add 3 to 5 times the amount of water relative to the mixture, boil for 2 to 4 hours, filter, and concentrate to a paste with a relative density of 1.27 to 1.29 at 70°C;

[0049] The third step is to mix the paste obtained in the first step and the second step, and dry under reduced pressure and vacuum...

Embodiment 1

[0058] Embodiment 1: oral liquid

[0059] Take 140g of Osmanthus chinensis, 180g of scutellaria, 90g of Nitraria japonica, 250g of dry field grass, 180g of kidney grass, 200g of black medicine leaves, 220g of seven leaves, 140g of parasitic yellow, 200g of chalk, 200g of yellow back grass, and 250g of sage vine , 150g maple pear, 200g sky shell, 300g tangerine, 100g manshuxing, 180g fragrant structure, 220g mallow fruit and 280g juhuacao;

[0060] Its preparation method comprises the following steps:

[0061] In the first step, mix Osmanthus chinensis, scutellaria, Nitraria japonica, dry field grass, kidney grass, black medicine leaves, seven leaf seven and parasitic yellow, and add 60% ethanol with an alcohol concentration of 4 times the amount of the mixture to reflux Extract 4 times, 2 hours each time, filter, combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.31 at 70°C, and set aside;

[0062] In the second step, mix the remainin...

Embodiment 2

[0067] Embodiment 2: capsules

[0068] Take 160g of Osmanthus chinensis, 150g of scutellaria, 120g of Nitraria japonica, 200g of dry field grass, 220g of kidney grass, 170g of black medicine leaves, 260g of seven leaves, 100g of parasitic yellow, 240g of chalk, 180g of yellow back grass, and 280g of sage vine , 140g maple pear, 240g sky shell, 260g tangerine, 150g manshuxing, 160g fragrant structure, 250g mallow fruit and 250g juhuacao;

[0069] Its preparation method comprises the following steps:

[0070] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 90% relative to the quality of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first ...

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Abstract

The invention provides a traditional Chinese medicine contrast agent for gastrointestinal B ultrasound, and a preparation method for the traditional Chinese medicine contrast agent. The traditional Chinese medicine contrast agent comprises the following raw herbal materials: gleicheniaceae dicranopteris amplea, thyrocarpus sampsonii, sophora davidii, lindernia ruellioides (Colsm) Pennell., herminium bulleyi (Rolfe) Tang et Wang, radix linderae leaf, chloranthus japonicus Sieb., involucrate balanophora, chalk, themeda triandra, ceylon cynoglossum, root of dentiferous dendropanax, japanese metaplexis pericarp, tangerine pith, ilex aculcolata nakai, bark or root of littleflower stringbush, malva verticillata L., and floscopa scandens. The traditional Chinese medicine contrast agent has the benefits that the cost is low, the use is convenient and safe, toxic and side effects are avoided, the ratio of good development is increased, and the inspection accuracy is improved, so that more gastrointestinal diseases can be inspected through B ultrasound, a powerful basis is provided for clinical diagnosis, and the preparation process is simple and practical.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine imaging aid for gastrointestinal B-ultrasound and a preparation method thereof. Background technique [0002] Ultrasound image diagnosis is one of the important diagnostic methods in medicine. Ultrasound has three major effects on matter: one is mechanical action, because the ultrasonic energy is huge, it often makes the material particles vibrate at high frequency mechanically, thus producing crushing, agglomeration, and stirring effects. The second is the thermal effect. When the ultrasonic wave acts on the substance, its energy is absorbed by the substance, thus increasing the temperature of the substance. The third is cavitation. When the ultrasonic wave acts on the liquid, the area with weak internal stress in the liquid (such as microscopic bubbles, etc.) becomes sparse due to the huge change in the sound pres...

Claims

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Application Information

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IPC IPC(8): A61K49/22
Inventor 徐永通黄楠孙建东
Owner 徐永通
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