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Composition for dispelling effects of alcohol and protecting liver and preparation method of composition

A technology for detoxifying and protecting the liver and composition, which is applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve problems such as high cost and complicated formula, and achieve the effect of simple operation and easy realization.

Inactive Publication Date: 2015-12-09
北京世纪合辉医药科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The embodiment of the present invention provides a hangover-protecting liver composition and its preparation method to solve the technical problems of complex formula and high cost of existing hangover-protecting liver products

Method used

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  • Composition for dispelling effects of alcohol and protecting liver and preparation method of composition
  • Composition for dispelling effects of alcohol and protecting liver and preparation method of composition
  • Composition for dispelling effects of alcohol and protecting liver and preparation method of composition

Examples

Experimental program
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Effect test

Embodiment 1

[0047] This example provides a hangover-healing and liver-protecting composition, which is made of the following raw materials in weight fractions: 50 parts of turmeric, 100 parts of emblica, 100 parts of myrobalan, 50 parts of olive, 150 parts of dextrin, and 6 parts of steviol glycoside .

[0048] The preparation method of the anti-alcoholic and liver-protecting composition of this embodiment, the specific operation steps are as follows:

[0049] 1) Extract turmeric and prepare turmeric extract:

[0050] A: After the turmeric is crushed through a 10-mesh sieve, add ethanol with a mass concentration of 75% to heat and reflux for extraction twice, and combine the filtrate to obtain an extract; wherein the amount of each extraction solvent is 8 times the weight of turmeric, and the extraction temperature is 50 ℃, the extraction time is 2h;

[0051] B: Concentrate the extract prepared in step A to a relative density of 1.20 at a temperature of 60° C. and a vacuum of 0.07 MPa t...

Embodiment 2

[0069] This example provides a hangover-healing and liver-protecting composition, which is made of the following raw materials in weight fractions: 150 parts of turmeric, 150 parts of emblica, 50 parts of myrobalan, 100 parts of olive, 50 parts of dextrin, and 3 parts of steviol glycoside .

[0070] The preparation method of the anti-alcoholic and liver-protecting composition of this embodiment, the specific operation steps are as follows:

[0071] 1) Extract turmeric and prepare turmeric extract:

[0072] A: After the turmeric is crushed through a 12-mesh sieve, add ethanol with a mass concentration of 50% and heat and reflux for extraction 3 times, and combine the filtrate to obtain an extract; wherein the amount of each extraction solvent is 10 times the weight of turmeric, and the extraction temperature is 60 ℃, the extraction time is 1h;

[0073] B: Concentrate the extract prepared in step A to a relative density of 1.10 at a temperature of 70° C. and a vacuum of 0.08 M...

Embodiment 3

[0091] This example provides a composition for hangover and liver protection, which is made of the following raw materials in weight fractions: 100 parts of turmeric, 50 parts of emblica, 150 parts of myrobalan, 150 parts of olive, 100 parts of dextrin, and 4 parts of steviol glycoside .

[0092] The preparation method of the anti-alcoholic and liver-protecting composition of this embodiment, the specific operation steps are as follows:

[0093] 1) Extract turmeric and prepare turmeric extract:

[0094] A: After turmeric is pulverized through a 20 mesh sieve, adding mass concentration of 80% ethanol to heat and reflux for extraction 3 times, and combining three filtrates to obtain an extract; wherein the amount of ethanol extracted each time is 8 times the weight of turmeric, and the extraction temperature is 70°C, the extraction time is 0.5h;

[0095] B: Concentrate the extract prepared in step A to a relative density of 1.15 at a temperature of 65° C. and a vacuum of 0.075...

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Abstract

An embodiment of the invention belongs to the technical field of healthcare products and discloses a composition for dispelling effects of alcohol and protecting the liver and a preparation method of the composition. The composition for dispelling the effects of alcohol and protecting the liver is prepared from, by weight, 50-150 parts of rhizoma curcumae longae, 50-150 parts of fructus phyllanthi, 50-150 parts of medicine terminalia fruits and 50-150 parts of olives, wherein the rhizoma curcumae longae has an anti-inflammatory function, a liver protection function and a cholagogue effect; the fructus phyllanthi and the medicine terminalia fruits have liver protection effects and are capable of realizing reduction of liver injuries and realizing an anti-liver fibrosis function; polyphenols in the olives have functions of blood purifying, liver soothing, stomach harmonizing and qi regulating and are capable of effectively alleviating symptoms such as headache, dizziness, stomachache, nausea, poor mental state and the like caused by alcohol consumption. Choleresis increasing and gallbladder contract promoting functions of the rhizoma curcumae longae and lipid metabolism promotion and gastrointestinal peristalsis promotion functions of the olives promote liver protection functions of the fructus phyllanthi and the medicine terminalia fruits, and remarkable healthcare effects of dispelling the effects of alcohol and protecting the liver are achieved owing to synergistic interaction of the four ingredients. The preparation method of the composition is suitable for industrial popularization and application.

Description

technical field [0001] The invention relates to the technical field of health care products, in particular to a composition for hangover and liver protection and a preparation method thereof. Background technique [0002] As an important detoxification organ of the human body, the liver has dual blood supply from the hepatic artery and the hepatic vein. Chemical liver injury is liver injury caused by chemical hepatotoxic substances, including alcohol, chemical poisons in the environment and certain drugs. However, in recent years, with the development of my country's national economy and changes in lifestyle and diet, alcoholic liver injury has become the main cause of liver injury after viral hepatitis, and it is showing a gradual upward trend. Alcoholic liver injury is a toxic liver disease caused by excessive drinking. More than 80% of heavy drinkers have fatty liver, 10% to 35% will develop into alcoholic hepatitis, and 10% to 20% will develop into liver cirrhosis. Pub...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P39/02A61P1/16
Inventor 陈文明
Owner 北京世纪合辉医药科技股份有限公司
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