Medicine for treating spleen and stomach deficiency-cold type reflux esophagitis and preparation method
A technology for reflux esophagitis and spleen-stomach deficiency-cold type, applied in the field of traditional Chinese medicine, can solve problems such as injury to the spleen and yang, and achieve the effect of disease control, rapid disease progression, and long-term curative effect
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[0059] The present invention also provides the preparation method of above-mentioned medicine as oral liquid, it comprises:
[0060] The first step is to take the orchid and extract it with supercritical carbon dioxide to obtain the orchid oil, and then use water-soluble cyclodextrin for inclusion to obtain the inclusion liquid;
[0061] In the second step, take cubeb, fritillary fritillary, cork, astragalus, octopus, dogwood, puhuang, Bupleurum, hedyotis diffusa, American ginseng, Polygonum water and green arrow, grind them separately, mix them together, and use Ethanol extraction to obtain extraction powder;
[0062] In the third step, the remaining components are pulverized separately, mixed together, and extracted with water;
[0063] The fourth step is to mix the products obtained from the first step to the third step together, add 3-10 g of flavoring agent, adjust the pH value to 7.5-8.5, stir well, potting in 50 ml, and sterilizing the package.
[0064] Further in the...
Embodiment 1
[0076] Embodiment 1 oral liquid
[0077] Get 15g of red door orchid, adopt supercritical carbon dioxide extraction, the extraction condition of described supercritical carbon dioxide fluid extraction is: extraction pressure is 30MPa, and extraction temperature is 50 ℃, CO 2 The flow rate is 25.0kg / h, static extraction for 2 hours, and then dynamic extraction for 3 hours, the separation pressure of the separation tank is 4.0MPa, and the separation temperature is 60°C to obtain the red door orchid oil, which is water-soluble ring When the dextrin is included, use mechanical stirring method, take 8g of water-soluble cyclodextrin to make a saturated aqueous solution, add 1ml of red door orchid oil, control the temperature at 50°C, stir for 3h, and control the stirring speed at 300r / min , to obtain the clathrate liquid of red door orchid oil; take Cucumber 15g, Fritillaria 35g, Phellodendron 40g, Astragalus 15g, octopus 15g, Cornus officinalis 15g, Puhuang 15g, Bupleurum 25g, Hedyo...
Embodiment 2
[0091] Embodiment 2 Granules
[0092] Get 15g of red door orchid, adopt supercritical carbon dioxide extraction, the extraction condition of described supercritical carbon dioxide fluid extraction is: extraction pressure is 30MPa, and extraction temperature is 50 ℃, CO 2 The flow rate is 25.0kg / h, static extraction for 2 hours, and then dynamic extraction for 3 hours, the separation pressure of the separation tank is 4.0MPa, and the separation temperature is 60°C to obtain the red door orchid oil, which is water-soluble ring When the dextrin is included, use mechanical stirring method, take 8g of water-soluble cyclodextrin to make a saturated aqueous solution, add 1ml of red door orchid oil, control the temperature at 50°C, stir for 3h, and control the stirring speed at 300r / min , to obtain the clathrate liquid of red door orchid oil; take Cucumber 15g, Fritillaria 35g, Phellodendron 40g, Astragalus 15g, octopus 15g, Cornus officinalis 15g, Puhuang 15g, Bupleurum 25g, Hedyotis...
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