Medicine for treating spleen and stomach deficiency-cold type reflux esophagitis and preparation method

A technology for reflux esophagitis and spleen-stomach deficiency-cold type, applied in the field of traditional Chinese medicine, can solve problems such as injury to the spleen and yang, and achieve the effect of disease control, rapid disease progression, and long-term curative effect

Inactive Publication Date: 2015-12-16
王栩
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In the current clinical practice, according to traditional Chinese medicine theory, syndromes of stagnant heat in the liver and stomach and disharmony between the liver and stomach are more common, but there are also syndromes of deficiency and cold in the spleen and stomach, especially in middle-aged and elderly people. Then it weakens, the spleen yang is weak, and the cold arises from it; in addition, the usual bad habits such as eating raw and cold food, greasy food, tobacco and alcohol will damage the spleen yang and help the cold; and the excessive use of cold and cold medicines will make the cold even colder

Method used

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preparation example Construction

[0059] The present invention also provides the preparation method of above-mentioned medicine as oral liquid, it comprises:

[0060] The first step is to take the orchid and extract it with supercritical carbon dioxide to obtain the orchid oil, and then use water-soluble cyclodextrin for inclusion to obtain the inclusion liquid;

[0061] In the second step, take cubeb, fritillary fritillary, cork, astragalus, octopus, dogwood, puhuang, Bupleurum, hedyotis diffusa, American ginseng, Polygonum water and green arrow, grind them separately, mix them together, and use Ethanol extraction to obtain extraction powder;

[0062] In the third step, the remaining components are pulverized separately, mixed together, and extracted with water;

[0063] The fourth step is to mix the products obtained from the first step to the third step together, add 3-10 g of flavoring agent, adjust the pH value to 7.5-8.5, stir well, potting in 50 ml, and sterilizing the package.

[0064] Further in the...

Embodiment 1

[0076] Embodiment 1 oral liquid

[0077] Get 15g of red door orchid, adopt supercritical carbon dioxide extraction, the extraction condition of described supercritical carbon dioxide fluid extraction is: extraction pressure is 30MPa, and extraction temperature is 50 ℃, CO 2 The flow rate is 25.0kg / h, static extraction for 2 hours, and then dynamic extraction for 3 hours, the separation pressure of the separation tank is 4.0MPa, and the separation temperature is 60°C to obtain the red door orchid oil, which is water-soluble ring When the dextrin is included, use mechanical stirring method, take 8g of water-soluble cyclodextrin to make a saturated aqueous solution, add 1ml of red door orchid oil, control the temperature at 50°C, stir for 3h, and control the stirring speed at 300r / min , to obtain the clathrate liquid of red door orchid oil; take Cucumber 15g, Fritillaria 35g, Phellodendron 40g, Astragalus 15g, octopus 15g, Cornus officinalis 15g, Puhuang 15g, Bupleurum 25g, Hedyo...

Embodiment 2

[0091] Embodiment 2 Granules

[0092] Get 15g of red door orchid, adopt supercritical carbon dioxide extraction, the extraction condition of described supercritical carbon dioxide fluid extraction is: extraction pressure is 30MPa, and extraction temperature is 50 ℃, CO 2 The flow rate is 25.0kg / h, static extraction for 2 hours, and then dynamic extraction for 3 hours, the separation pressure of the separation tank is 4.0MPa, and the separation temperature is 60°C to obtain the red door orchid oil, which is water-soluble ring When the dextrin is included, use mechanical stirring method, take 8g of water-soluble cyclodextrin to make a saturated aqueous solution, add 1ml of red door orchid oil, control the temperature at 50°C, stir for 3h, and control the stirring speed at 300r / min , to obtain the clathrate liquid of red door orchid oil; take Cucumber 15g, Fritillaria 35g, Phellodendron 40g, Astragalus 15g, octopus 15g, Cornus officinalis 15g, Puhuang 15g, Bupleurum 25g, Hedyotis...

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PUM

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Abstract

The invention provides medicine for treating reflux esophagitis. The medicine is prepared from piper cubeba, poria cocos, mangnolia officinalis, thunberg fritillary bulb, cortex phellodendri, galangal, myristica fragrans, milkvetch roots, cuttlebone, selaginella tamariscina, dendrobium, cornus officinalis, radix angelicae, cattail pollen, bupleurum, spreading hedyotis herb, American ginseng, polygonum hydropiper, orchis morio and nodding clinacanthus. The medicine has the advantages that clinical symptoms of reflux esophagitis can be fast controlled, mucous membrane histopathologic changes can be fast restored, the state of the illness can be fast controlled, the long-term therapeutic effect is good, and few side effects exist, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating reflux esophagitis of spleen-stomach deficiency-cold type. Background technique [0002] Reflux esophagitis (refluxesopHagitis, RE) refers to the reflux of gastric and (or) duodenal contents into the esophagus, causing inflammation, erosion, ulceration and fibrosis of the esophageal carrier membrane, which belongs to gastroesophageal reflux disease (gastroesoHaealrefluxdisease, GERD) category. There may be typical symptoms such as heartburn and acid reflux, as well as atypical symptoms such as heating, epigastric pain, nausea, retrosternal pain, etc., and extraesophageal manifestations such as asthma, chronic cough, foreign body sensation in the throat, hoarseness, etc. The main complications were esophageal stricture, Barrett's esophagus, and esophageal adenocarcinoma. The disease is very common in western countries, about 10% to 20...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P1/04A61K35/618
Inventor 不公告发明人
Owner 王栩
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