Traditional Chinese medicine for assisting treatment on femoral neck fracture and preparation method thereof

A technique for adjuvant treatment of femoral neck fractures, applied in the field of pharmacy, can solve problems such as long healing time of femoral neck fractures, avascular necrosis of the femoral head, troubles for patients and their families, etc., to shorten the healing time of fractures, increase the proportion, and reduce or pain Effect

Inactive Publication Date: 2015-12-23
姜永杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Due to the long healing time of femoral neck fractures, the clinical healing time is generally as long as 12-24 weeks (see "Practical Orthopedics"), and it is also easy to cause fracture nonunion and avascular necrosis of the femoral head, etc., causing great harm to patients and their families. big trouble

Method used

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Examples

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Effect test

preparation example Construction

[0045] Wherein, when the dosage form of the Chinese medicine is a granule, its preparation method comprises the following steps:

[0046] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% relative to the mixture 4 to 8 times, heat to boiling and reflux for 3 to 5 hours, filter, and use the reflux liquid as a solvent , using the filter residue as the solute, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, and then concentrate it under reduced pressure at a vacuum of 0.06-0.09Mpa to 50-60°C with a relative density of 1.04 ~1.10 paste, spray drying, the air inlet temperature of the spray dryer is 160~175℃, and the air outlet temperature is 80~85℃, and then crushed into powder to make dry paste powder;

[0047] Step 2: Add 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin to the obtained dry cream powder to form granules, and dry at ...

Embodiment 1

[0055] Embodiment 1: Granules

[0056] Take 180g of vine vine, 140g of deer wrinkle, 250g of grass sage, 170g of reed vine, 200g of rhizome, 150g of hibiscus, 200g of cat's claw, 280g of bristle grass, 120g of yellow ox tea, 150g of phlegm fire grass, 80g of astronomy grass, 240g of kumquat root, 180g of cypress, 260g of carrageenan, 150g of chrysalis, 180g of lotus bean vegetable and 240g of golden grass;

[0057] Its preparation method comprises the following steps:

[0058] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 95% that is 5 times that of the mixture, heat to boiling and reflux for 3 hours, filter, use the reflux liquid as the solvent, and use the filter residue as the solute. The percolation method slowly percolates at a rate of 2ml per minute, collects the percolation liquid, and then concentrates it under reduced pressure at a vacuum of 0.8Mpa to a paste with a relative density of 1.05 at 55°C...

Embodiment 2

[0060] Embodiment 2: powder

[0061] Take 210g of vine, 120g of deer, 280g of grass, 140g of reed, 220g of chrysanthemum, 100g of hibiscus, 240g of cat's claw, 260g of bristle grass, 150g of yellow cattle tea, 130g of phlegm fire grass, 120g of astronomy grass, 200g of kumquat root, 200g of cypress, 240g of carrageenan, 180g of chrysalis, 150g of lotus bean vegetable and 270g of golden grass;

[0062] Its preparation method comprises the following steps:

[0063] In the first step, the raw medicinal materials are mixed in proportion and pulverized into powder;

[0064] In the second step, add the powder obtained in the first step to soak in cold water for 8 hours, decoct with a slow fire for 5 hours, filter the decoction to obtain the first filtrate, the quality of the added water is the first step 2 times the mass of the powder obtained;

[0065] In the third step, add the filter residue obtained by the second step of filtration into cold water again, decoct with a slow fi...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for assisting the treatment on femoral neck fracture and a preparation method thereof. The traditional Chinese medicine comprises the following active ingredients: flexuose climbing fern, rhynchosia volubilis, phlomis umbrosa, stem of falsenettleleaf pepper, curious kadsura root stem, hibiscus tiliaceus, radix ranunculi ternate, adiantum capillus veneris, cratoxylon ligustrinum, murdannia bracteata, acmella ciliate, oval kumquat root, asparagus, pelvetia silquosa, stachys sieboldii, drymaria cordata and hedyotis acutangula champ. The traditional Chinese medicine has beneficial effects that the traditional Chinese medicine for assisting the treatment on the femoral neck fracture can be matched with a traditional treatment method to use, so that the ratio of the bone healing patient is increased, the fracture healing time is shortened, and the pain of the patient is rapidly alleviated or eliminated.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for auxiliary treatment of femoral neck fracture and a preparation method thereof. Background technique [0002] Femoral neck fracture refers to the femoral neck fracture caused by osteoporosis, degeneration of hip muscles in the elderly, unresponsiveness or severe trauma. Femoral neck fractures often occur in the elderly. With the prolongation of life expectancy, the incidence rate is increasing day by day. Especially with the aging of the population, it has become a serious social problem. In its clinical treatment, there are two main problems of fracture nonunion and avascular necrosis of the femoral head. [0003] Femoral neck fractures mostly occur in the elderly, and the incidence rate of women is higher than that of men. Because the elderly often have different degrees of osteoporosis, and women are relatively less active than men, and due...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8965A61P19/08
Inventor 姜永杰孙凤香夏宝芳刘佳
Owner 姜永杰
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