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Expandable Implantable Catheter

A technology of catheters and valves, applied in the field of expandable implantable catheters, which can solve problems such as uncomfortable catheters and long-term functionality that have not been proven

Active Publication Date: 2020-07-28
CARNEGIE MELLON UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, young children may rapidly outgrow the implanted catheter and may require reoperation and replacement
To date, only tissue-engineered catheters or valved catheters have been proposed to accommodate patient growth, but these solutions are time and cost-intensive and by and large have not yet proven to be functional in the long term

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0075] Example 1: A first plastically deformable material that can be used in an implantable catheter

[0076] Figure 7A A stress / strain curve is depicted for a first plastically deformable material that can be used to make a plastically deformable and implantable catheter. The material has an average yield strength of about 2.1 MPa and an ultimate tensile strength of about 5 MPa. The material also exhibits elastic deformation at yield strength, characterized by an average elastic modulus of about 5.9 MPa. In the portion of the stress / strain curve where the material transitions from an elastically deformable mode to a plastically deformable mode, the material exhibits an elongation of an average of 36% over the original length at the yield stress point. Since the extended region of the stress / strain curve indicates plastic deformability as opposed to elastic deformability, such materials may advantageously be used in plastically deformable catheters that can expand to mee...

Embodiment 2

[0077] Example 2: Second plastically deformable material that can be used in implantable catheters

[0078] Figure 7B A stress / strain curve is depicted for a second plastically deformable material that can be used to make a plastically deformable and implantable catheter. The material exhibited an average yield strength of about 1.7 MPa and an ultimate tensile strength of about 5.5 MPa. The material is also elastically deformable at yield strength, characterized by an average elastic modulus of about 7.4 MPa. In the portion of the stress / strain curve where the material transitions from an elastically deformable mode to a plastically deformable mode, the material exhibits an elongation of an average of 24% over the original length at the yield stress point. Since the extended region of the stress / strain curve indicates plastic deformability as opposed to elastic deformability, such materials may advantageously be used in plastically deformable catheters that can expand to ...

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Abstract

An expandable valved catheter for pediatric right ventricular outflow tract (RVOT) reconstruction is disclosed. Valved catheters can provide long-term patency and resistance to thrombus and stenosis. The valved catheter can expand radially and / or longitudinally to accommodate the growing anatomy of the patient. Further, methods are disclosed for the production of valvated catheters based in part on plastically deformable biocompatible polymers, as well as computer-optimized valve designs developed for such expandable valvated catheters.

Description

[0001] claim priority [0002] This application requires the U.S. Provisional Application entitled "Expandable Valve Conduit for Pediatric Right Ventricular Outflow Tract (RVOT) Reconstruction," filed March 8, 2013 Priority to No. 61 / 851,487, the disclosure of which is incorporated herein by reference in its entirety. Background technique [0003] Catheter selection for right ventricular outflow tract (RVOT) reconstruction presents challenges in the management of many congenital heart diseases including tetralogy of Fallot with pulmonary atresia, truncus arteriosus, Displacement of the great arteries in pulmonary stenosis, congenital aortic stenosis / insufficiency, and variants of such conditions. After the invention of cryopreservation methods in the early 1980's, and especially with the increasing availability of use in a wide range of graft sizes, allografts have become the catheter of choice for physicians performing RVOT reconstruction surgery. In many instances, such a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/24
CPCA61F2250/006A61F2250/0007A61F2/2475A61F2210/0004A61F2220/0075A61F2250/0082A61F2002/30706A61F2/2415A61F2/2412A61F2/2418G05B19/4099G05B2219/42155
Inventor C·D·伯恩斯坦A·卡尔拉
Owner CARNEGIE MELLON UNIV
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