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Surgical suture with analgesic and antibacterial effect and preparation method thereof

A suture and high-quality technology, applied in the field of medical materials, can solve the problems of skin tissue inflammation, non-absorbable medical suture, wound bacterial infection, etc., achieve good coagulation effect, good biodegradability, and promote healing effects

Inactive Publication Date: 2016-04-06
张德信
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] As a kind of foreign body, suture exists in the incision tissue, which can easily cause inflammation in the skin tissue. The sutured wound is easily infected by bacteria in the surrounding environment of the body. It does not have certain bactericidal and anti-inflammatory effects, and it is easy to cause wound infection after use
And most of them are non-absorbable medical sutures. Removal of sutures after surgery will bring great pain to patients, which is difficult for most consumers to accept.

Method used

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  • Surgical suture with analgesic and antibacterial effect and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1 An analgesic and antibacterial medical suture, prepared from the following main raw materials (80g per serving): 7 parts of polylactic acid, 8 parts of tile grass, 7 parts of kapok, 3 parts of dried sandalwood, 9 parts of cinnamon bark 9 parts of Dayeteng, 11 parts of Dajindao, 9 parts of Stephania vine, 5 parts of Polygonatum, 7 parts of Chuanmuxiang, 0.6 parts of enoxacin, appropriate amount of dicumyl peroxide, and appropriate amount of mannitol.

[0035] A kind of analgesic and antibacterial medical suture preparation steps are as follows:

[0036] (1) Dry the kapok, cassia bark and Stephania vine, crush them into coarse powder, put them in a glass container, add 50% ethanol (the amount is twice the mass of the medicine powder) as a solvent, soak for 20 hours, and put them in the infiltration percolate in the container to obtain percolate;

[0037] (2) Slice the tile grass and Chuanmuxiang, put them in a non-iron container, add rice wine (the dosage is 2...

Embodiment 2

[0045] Example 2 An analgesic and antibacterial medical suture, prepared from the following main raw materials (20g per serving): 11 parts of polylactic acid, 12 parts of tile grass, 11 parts of kapok, 5 parts of dried sandalwood, 15 parts of cassia bark 13 parts of Dayeteng, 15 parts of Dajindao, 13 parts of Stephania vine, 7 parts of Polygonatum, 10 parts of Chuanmuxiang, 0.8 parts of enoxacin, appropriate amount of dicumyl peroxide, and appropriate amount of mannitol.

[0046] A kind of preparation steps of analgesic and antibacterial medical suture is as follows:

[0047] (1) Dry the kapok, cassia bark and Stephania vine, crush them into coarse powder, put them in a glass container, add 70% ethanol (3 times the mass of the medicine powder) as a solvent, soak for 30 hours, and put them in the infiltration percolate in the container to obtain percolate;

[0048] (2) Slice the tile grass and Chuanmuxiang, put them in a non-iron container, add rice wine (the dosage is 30% o...

Embodiment 3

[0057] Example 3 An analgesic and antibacterial medical suture, prepared from the following main raw materials (50g for each part): 8 parts of polylactic acid, 9 parts of tile grass, 8 parts of kapok, 3.5 parts of dried sandalwood, 11 parts of cassia bark 10 parts of Dayeteng, 12 parts of Dajindao, 10 parts of Stephania vine, 5.5 parts of Polygonatum, 8 parts of Chuanmuxiang, 0.65 parts of enoxacin, appropriate amount of dicumyl peroxide, and appropriate amount of mannitol.

[0058] A kind of analgesic and antibacterial medical suture preparation steps are as follows:

[0059] (1) Dry the kapok, cassia bark and Stephania vine, crush them into coarse powder, put them in a glass container, add 55% ethanol (the amount is twice the mass of the medicine powder) as a solvent, soak for 23 hours, and put them in the infiltration percolate in the container to obtain percolate;

[0060] (2) Slice the tile grass and Chuanmuxiang, put them in a non-iron container, add rice wine (the am...

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Abstract

The invention discloses a surgical suture with analgesic and antibacterial effect. The surgical suture is mainly prepared from, by weight, 7-11 parts of polylactic acid, 8-12 parts of szechuan melandium root, 7-11 parts of common bombax flower, 3-5 parts of syris wightiana, 9-15 parts of bark of cinnamomum iners, 9-13 parts of tinomiscium, 11-15 parts of all-grass of neolepisorus ovatus, 9-13 parts of stephania japonica root, 5-7 parts of siberian solomonseal rhizome, 7-10 parts of common vladimiria root, 0.6-0.8 part of enoxacin, appropriate dicumyl peroxide and appropriate mannitol. The surgical suture has good analgesic and antibacterial effect and can effectively prevent wound infection; the surgical suture refined from the polylactic acid fine in biodegradability and some common Chinese herbs is long in tension maintaining time, and capable of ensuring operative wounds heal completely, and has good biocompatibility and biodegradability.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to an analgesic and antibacterial medical suture and a preparation method. Background technique [0002] Over the past ten years, the growth of global health care expenses has been higher than the growth of GDP in the same period. China's medical device market has continued to grow at an annual growth rate of 20-27% in the past ten years, much higher than the 7-10% of the international market, but Chinese products account for less than 3% of the world market, which is as high as the international market. Compared with technical biomedical materials and their products accounting for more than 40% of the medical device market, China's biomedical material industry is very weak, with a serious shortage of raw material suppliers and production bases, and an unreasonable industrial technology structure. With the development of biomedicine and polymer material science, biodegradable medic...

Claims

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Application Information

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IPC IPC(8): A61L17/12A61L17/00
CPCA61L17/005A61L17/12A61L2300/216A61L2300/30A61L2300/402A61L2300/406A61L2300/45
Inventor 不公告发明人
Owner 张德信
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