Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Medicament for treating periodontitis

A technology of medicine and yam, which is applied in the field of medicine for treating periodontitis, can solve the problems of leukopenia, failure to prevent frequent recurrence, etc., and achieve the effect of definite curative effect, promotion of reconstruction and healing, and low price

Inactive Publication Date: 2016-04-13
刘思娟
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, only local treatment and systemic anti-inflammatory treatment could only temporarily relieve symptoms, but could not prevent frequent recurrence, and often produced side effects, such as allergic reactions, gastrointestinal irritation symptoms, and leukopenia.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0054] The present invention also provides a method for preparing the above-mentioned medicine. When the dosage form of the medicine is dentifrice, it is specifically:

[0055] In the first step, take Southern Adenophora, Daqingye, Pearl Ginseng, Coptis, Cornus, Chinese Yam, Galla Chinensis, Scrophulariaceae, Drynaria fortunei, Rhubarb, Cervix and Lantern Flower, mix according to the stated weight, and smash into 100 meshes. Powder, using supercritical CO under pressure 35~45MPa and temperature 45~55℃ 2 Extract for 1.5-2.5 hours, collect the extract, add 70-80% ethanol to the extract, heat to 50-70°C, keep stirring, after melting, filter while hot, discard the suspended matter and insoluble matter, let the filtrate cool and precipitate Precipitation, filtration, concentration under reduced pressure, drying, and crushing into 200 mesh powder;

[0056] In the second step, the remaining components are mixed according to the stated weight to obtain a mixture, crushed into 100 mesh powd...

Embodiment 1

[0063] Example 1 Preparation of tooth powder 1

[0064] Take 35g of southern Adenophora, 60g of Daqingye, 40g of ginseng, 35g of Coptis, 40g of cornus, 25g of Chinese yam, 35g of gallnut, 25g of Scrophulariaceae, 45g of Drynaria fortunei, 20g of Rhubarb, 25g of Ceratophyllum and 15g of Lantern Flower. Mix according to the weight and pulverize into powder of 100 mesh. Under the conditions of pressure of 40MPa and temperature of 50℃, supercritical CO 2 After extracting for 2 hours, collect the extract, add 80% ethanol to the extract, heat to 60°C, keep stirring, dissolve and filter while hot, discard the suspended matter and insoluble matter, let the filtrate cool, and precipitate the precipitate, filter, reduce Compressed, concentrated, dried, and crushed into 200 mesh powder, 35g of nutmeg, 30g of gardenia, 25g of ginseng, 30g of Sargentodoxa cuneata, 20g of coriander, 15g of mountain white chrysanthemum, 15g of Yunshi root, 30g of Anemarrhena, and 25g of cylindrica , 30g of Ajug...

Embodiment 2

[0065] Example 2 Preparation of Tooth Powder 2

[0066] Take 40g South Ginseng, 65g Daqingye, 45g Pearl Ginseng, Coptis 40g, Cornus 45g, Chinese Yam 30g, Galla Chinensis 40g, Scrophulariae 30g, Rhizoma Drynariae 50g, Rhubarb 20g, Ceratophyllum 25g and Lantern Flower 15g. Mix according to the weight and pulverize into powder of 100 mesh. Under the conditions of pressure of 40MPa and temperature of 50℃, supercritical CO 2 After extracting for 2 hours, collect the extract, add 80% ethanol to the extract, heat to 60°C, keep stirring, dissolve and filter while hot, discard the suspended matter and insoluble matter, let the filtrate cool, and precipitate the precipitate, filter, reduce Compressed, concentrated, dried, and pulverized into 200 mesh powder, 40g nutmeg, 35g gardenia, 30g ginseng, 35g Sargentodoxa cuneata, 20g coriander, 15g mountain white chrysanthemum, Yunshi root 15g, Zhimu 30g, and 25g , 30g of Ajuga grass and 25g of Longzhaocai were mixed according to the stated weight...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a medicament for treating periodontitis. The medicament is prepared from the bulk pharmaceuticals of adenophora tetraphylla, indigowoad leaf, panax pseudo-ginseng, semen myristicae, fructus gardenia, coptis root, dogwood, Chinese yam, gorgon euryale seed, sargentg loryvine stem, Chinese gall, figwort, fortune's drynaria rhizome, rhaponticum, Isodon amethystoides, compositae aster ageratoides, mysore thorn root, Chinese pyrola herb, common anemarrhena, Chinese enkianthus, fructus broussonetiae, decumbent bugle herb and pteridium aquilinum. Compared with single western medicine treatment, the medicament can activate the defense mechanisms of organisms and prompt rebuilding and healing of periodontium, has high compliance, a definite curative effect and less side effects, is low in price, does not cause the adverse reaction of drug resistance enhancement of periodontal anaerobic bacteria, and is worthy of popularization and application.

Description

Technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating periodontitis. Background technique [0002] Periodontitis has a complex etiology and is the first cause of tooth loss in adults. According to the third national oral health epidemiological survey, 80%-97% of adults in my country currently suffer from different degrees of periodontal disease. The prevalence after 35 years of age has increased significantly, reaching a peak in 40-50 years of age, and the cause Complex and diverse, individual differences are large, and radical cure is difficult. Periodontal treatment is mainly local treatment, that is, supragingival cleansing, subgingival curettage, periodontal surgery and other methods are used to remove the granulation tissue on the inner wall of the periodontal pocket, trim the diseased alveolar bone, and create conditions for periodontal reattachment. Systemic application of antibacteria...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/90A61K36/8964A61P1/02A61K35/64
CPCA61K36/90A61K9/006A61K9/08A61K9/148A61K36/11A61K36/126A61K36/185A61K36/195A61K36/25A61K36/28A61K36/315A61K36/342A61K36/344A61K36/40A61K36/45A61K36/48A61K36/53A61K36/60A61K36/62A61K36/704A61K36/708A61K36/718A61K36/744A61K36/808A61K36/855A61K36/88A61K36/8945A61K36/896A61K36/8964A61K2236/37
Inventor 刘思娟
Owner 刘思娟
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com